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ClinicalTrials.gov public records Last synced Oct 19, 2026, 9:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Memory Improvement Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Training Language and Literacy for Children Who Use CIs

NCT03582566
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Phonological Awareness, Working Memory, Phonological Awareness + Working Memory, Active Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
5 Years to 7 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
2
States / cities
Tallahassee, Florida • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 19, 2026, 9:09 AM EDT
Not listed Early Phase 1 Interventional

Responsive Neurostimulation for Post-Traumatic Stress Disorder

NCT04152993
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
NeuroPace® RNS® System
Device
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
25 Years to 60 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Phase 4 Interventional Results available

Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)

NCT02816138
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Nicotine
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional

Incorporating Multidimensional Psychosocial Interventions Improves the Well-being of Individuals With Epilepsy

NCT03484039
View directory record Official record
Conditions
Epilepsy, Seizure Disorder
Interventions
Medication Adherence, Seizure Documentation, Memory Improvement, Stress Management
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 88 Years
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Oct 19, 2026, 9:09 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Investigating Memory Retrieval Improvement in Healthy Subjects

NCT03312920
View directory record Official record
Conditions
Healthy Adults
Interventions
active anodal tDCS, sham tDCS, active cathodal tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Phase 2 Interventional Results available

Memory Improvement Through Nicotine Dosing (MIND) Study

NCT02720445
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Nicotine Transdermal Patch, Placebo Patch
Drug
Lead sponsor
University of Southern California
Other
Eligibility
55 Years to 90 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
36
States / cities
Scottsdale, Arizona • North Little Rock, Arkansas • Downey, California + 31 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Phase 4 Interventional

The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment

NCT02590874
View directory record Official record
Conditions
Mild Cognitive Impairment, Depression
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
50 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Phase 4 Interventional

A fMRI(Functional Magnetic Resonance Imaging) Research Study to Learn More About Multiple Sclerosis and Individuals Potentially Experiencing Memory Difficulties

NCT00315367
View directory record Official record
Conditions
Relapsing-Remitting Multiple Sclerosis
Interventions
Donepezil HCI (drug)
Drug
Lead sponsor
Neurognostics
Industry
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 16, 2007 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Phase 2 Interventional Results available

Depressed Mood Improvement Through Nicotine Dosing 2

NCT04433767
View directory record Official record
Conditions
Depressive Disorder
Interventions
Transdermal Nicotine patch
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 19, 2026, 9:09 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community

NCT04905849
View directory record Official record
Conditions
Aging, Cognitive Change
Interventions
Adaptive Cognitive Control Trainer (ACCT), Active Control App
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Home-based Brain Stimulation for Memory

NCT04783350
View directory record Official record
Conditions
Alzheimer Disease, Memory Loss
Interventions
Transcranial alternating current stimulation (tACS)
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
55 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rhythmically Entrained Exercise in Community-Dwelling Older Adults

NCT05462977
View directory record Official record
Conditions
Exercise, Gait, Cognitive Decline, Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Mild Cognitive Impairment, Respite Care, Mental Health, Depression, Music Therapy, Psychosocial Intervention, Cognition, Geriatric Assessment, Cognitive Dysfunction, Cognitive Aging, Outcome Assessment, Health Care, Balance, Fall, Walking, Affect, Physical Exertion, Memory Deficit, Memory Disorders, Memory Impairment, Neuropsychological Tests, Executive Function, Middle Aged, Healthy Aging, Elderly
Interventions
Group exercise program
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
55 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)

NCT00283010
View directory record Official record
Conditions
Aging
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training, Educational DVDs
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years and older
Enrollment
487 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional

Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults

NCT05043454
View directory record Official record
Conditions
Hypertension
Interventions
High Intensity Interval Training (HIIT) Exercise
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation

NCT03717922
View directory record Official record
Conditions
Brain Diseases, Memory Disorders, Learning Disabilities, Cognitive Impairment
Interventions
Low Intensity Focused Ultrasound Pulsation to Amygdala, Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
35 Years to 90 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Training Resiliency in Youth (TRY) Study

NCT03429465
View directory record Official record
Conditions
Attention Concentration Difficulty, Depression, Anxiety
Interventions
EVO Cognitive Remediation Game
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS)

NCT05524233
View directory record Official record
Conditions
Brain Fog
Interventions
Active Transcranial Direct Stimulation
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Characterizing the Synergistic Effects of Physical and Cognitive Training on Attention and Working Memory

NCT03032796
View directory record Official record
Conditions
Healthy Adults
Interventions
Body-Brain Trainer, Body Trainer, Brain Trainer, Expectancy Matched Control
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 80 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 19, 2026, 9:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cerebrovascular and Cognitive Improvement by Resveratrol (resVida) and Fruitflow-II (CCIRF-II)

NCT01766180
View directory record Official record
Conditions
Memory Impairment
Interventions
Fruitflow-II, resVida
Drug
Lead sponsor
Neurolgy Institute for Brain Health and Fitness
Other
Eligibility
50 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Oct 19, 2026, 9:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

An Assessment of Cognitive Improvement Training Among Mid-life Individuals

NCT03501706
View directory record Official record
Conditions
Delay Discounting
Interventions
Sequenced Recall of Digits--Auditory, Sequenced Reverse Recall of Digits--Auditory, Sequenced Recall of Words--Visual, Verbal Memory--Visual
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
40 Years to 60 Years
Enrollment
680 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 19, 2026, 9:09 AM EDT
Completed Phase 2 Interventional

Depressed Mood Improvement Through Nicotine Dosing 3

NCT05746273
View directory record Official record
Conditions
Depressive Disorder
Interventions
Transdermal Nicotine Patch, Transdermal Placebo Patch
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 19, 2026, 9:09 AM EDT
Enrolling by invitation Phase 4 Interventional

Quality Improvement and Practice Based Research in Neurology Using the EMR

NCT02670161
View directory record Official record
Conditions
Brain Tumors, Epilepsy, Migraine, Mild Cognitive Impairment, Concussion, Multiple Sclerosis, Neuropathy, Parkinson's, Restless Legs Syndrome, Stroke
Interventions
Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 100 Years
Enrollment
3,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 19, 2026, 9:09 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD: a Proof-of-concept Tele-health Study of Stimulant-induced Improvement in Neurocognitive Functioning.

NCT04386811
View directory record Official record
Conditions
ADHD
Interventions
Calcitriol, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 19, 2026, 9:09 AM EDT
Active, not recruiting Not applicable Interventional

Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment

NCT04558164
View directory record Official record
Conditions
Cognitive Dysfunction, Memory Disorders in Old Age
Interventions
Active Theta Burst Stimulation, Sham Theta Burst Stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
55 Years to 100 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 19, 2026, 9:09 AM EDT