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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

NCT04343573
View directory record Official record
Conditions
Leptomeningeal Metastases
Interventions
Involved-field Photon Radiation Therapy, Proton Craniospinal Irradiation (CSI), Neurocognitive Assessment, MDASI-BT and MDASI-SP
Radiation · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Up to 99 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness Based Couples Therapy

NCT02349217
View directory record Official record
Conditions
Breast Cancer
Interventions
Mindfulness-Based Relationship Enhancement (MBRE), Self-Help Materials, Pain Assessment, Questionnaires, Neurocognitive Tests, Cortisol Tests, Interviews
Behavioral · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury

NCT04706208
View directory record Official record
Conditions
Spinal Cord Injuries, Neuropathic Pain
Interventions
Cognitive Multisensory Therapy, Usual Care, Clinical Assessment, Magnetic Resonance Imaging (MRI), OPTIONAL: blood draw
Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Modeling and Testing Change in Mental Abilities in Childhood

NCT02459873
View directory record Official record
Conditions
Low Executive Function in Children
Interventions
Computer games to assess change in executive function skills
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
84 Months to 132 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 16, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans

NCT06217575
View directory record Official record
Conditions
Traumatic Brain Injury, Mild Traumatic Brain Injury, Aging, Cognitive Decline
Interventions
Alpha neurofeedback training, Visual Attention Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Terminated Phase 2 Interventional Results available

Sublingual Fentanyl for the Management of Breakthrough Pain

NCT02514252
View directory record Official record
Conditions
Advanced Cancers
Interventions
Fentanyl Sublingual Spray (FSS), Questionnaires, Mental Ability Tests, Study Diary
Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Sep 16, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional

Neurofeedback to Improve Working Memory in Mild Cognitive Impairment

NCT04566900
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Neurofeedback, Placebo
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional

TechMPower: Advancing HIV/SUD Care and Service Delivery for People in Re-entry

NCT07088770
View directory record Official record
Conditions
HIV (Human Immunodeficiency Virus), Substance Abuse Disorder
Interventions
Community Coalition CLS Workgroup/Network of Providers, Tech-mediated Training and Service Delivery, Multidisciplinary Implementation Team with Champion, Tech-mediated Peer Navigation Enhanced Case management (NCM)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kingston, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infections (STI) Testing and PrEP Initiation Among Rural Men Who Have Sex With Men

NCT06205368
View directory record Official record
Conditions
HIV Infections, STI, HIV Pre-exposure Prophylaxis
Interventions
Combine mobile app, Motivational interview, HIV/STI testing
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
473 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Transforming Psychotherapy for Chronically Ill Patients

NCT00520429
View directory record Official record
Conditions
Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive, Depression, Anxiety
Interventions
ACCES - Adjusting to Chronic Conditions with Education and Support
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2009 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

NCT01503086
View directory record Official record
Conditions
Brain Neoplasm, Recurrent Brain Neoplasm
Interventions
Cognitive Assessment, Computer-Assisted Cognitive Training, Psychosocial Assessment and Care, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
6 Years to 16 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
27
States / cities
Aurora, Colorado • Wilmington, Delaware • Washington D.C., District of Columbia + 24 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional

NRF for Improved Re-Entry Outcomes for Offenders With Brain Injury (Brain Injury RE)

NCT05708092
View directory record Official record
Conditions
Brain Injury
Interventions
NeuroResource Facilitation (NRF)
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Male only
Enrollment
1,022 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
New York, New York • Carlisle, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The First 20 Fire Academy Recruits Exercise Training Program

NCT03319394
View directory record Official record
Conditions
Physical Fitness
Interventions
The First Twenty, Comparison
Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Sep 16, 2026, 10:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)

NCT00908999
View directory record Official record
Conditions
Anosognosia, Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 28, 2011 · Synced Sep 16, 2026, 10:21 PM EDT
Active, not recruiting Phase 3 Interventional

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

NCT04804644
View directory record Official record
Conditions
Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Interventions
Biospecimen Collection, Magnetic Resonance Imaging, Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Survey Administration, Whole-Brain Radiotherapy
Procedure · Drug · Other + 1 more
Lead sponsor
NRG Oncology
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
227
States / cities
Phoenix, Arizona • Anaheim, California • Bellflower, California + 172 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Improving Thinking in Everyday Life After Covid-19

NCT04644172
View directory record Official record
Conditions
Covid-19, Cognitive Impairment
Interventions
Speed of Processing Training, Instrumental Activities of Daily Living Shaping, Transfer Package from CI Therapy, Usual Care
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

A Pilot of the Brief Relationship Checkup

NCT06011161
View directory record Official record
Conditions
Relationship Distress
Interventions
Brief Relationship Checkup (BRC)
Behavioral
Lead sponsor
Canandaigua VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 16, 2026, 10:21 PM EDT
Terminated Not applicable Interventional

Response to Relapse in Office-Based Opioid Treatment Trial

NCT03812107
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Moderate Treatment Approach, Intensive Treatment Approach
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Social Network Diffusion of COVID-19 Prevention for Diverse Criminal Legal Involved Communities

NCT05500274
View directory record Official record
Conditions
COVID-19
Interventions
Education, Motivational
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 16, 2026, 10:21 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia

NCT06644573
View directory record Official record
Conditions
Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder, REM Sleep Measurement, Insomnia, Insomnia Related to Specified Disorder, Insomnia Due to Other Mental Disorder, Insomnia Comorbid to Psychiatric Disorder, Insomnia Due to Anxiety and Fear, Insomnia Related to Another Mental Condition, Insomnia Disorders, Idiopathic Hypersomnia, Sleep Disorders, Circadian Rhythm, Post Trauma Nightmares, PTSD - Post Traumatic Stress Disorder, Sleep Quality, Anesthesia, Anxiety, Depression, Mental Health, Alzheimer Disease or Associated Disorder, Parkinsons, Circadian Rhythm, Circadian Dysregulation, PTSD, Post-Traumatic, Post-Traumatic Stress Disorder Complex, Military Combat Stress Reaction, Sleep, Military Activity, Veterans, Shift Work Sleep Disorder, Menopause Related Conditions, Pain, Cancer Pain, Athletes
Interventions
PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca, Continuous EEG Monitoring
Procedure · Drug · Device
Lead sponsor
Nyree Penn
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Sep 16, 2026, 10:21 PM EDT
Completed No phase listed Observational Results available

Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With ASD

NCT02708290
View directory record Official record
Conditions
Autistic Disorder, Autism, ASD
Interventions
MITA Prefrontal Synthesis exercises - each activity adapts to deliver the exercise that is at the exact level of difficulty appropriate for a child at any given point in time
Other
Lead sponsor
ImagiRation, LLC
Industry
Eligibility
2 Years to 12 Years
Enrollment
6,454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2020 · Synced Sep 16, 2026, 10:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Dual-Task Cost in Bilateral Hearing Loss

NCT05540535
View directory record Official record
Conditions
Bilateral Hearing Loss, Healthy Aging
Interventions
Gait assessment, Cognitive assessment
Other
Lead sponsor
New York University
Other
Eligibility
40 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Health and Wellness App on Employee Productivity

NCT05120310
View directory record Official record
Conditions
Sleep Disturbance, Mental Health Wellness 1
Interventions
The Calm App
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
1,029 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 16, 2026, 10:21 PM EDT
Completed Phase 3 Interventional

Brief Intervention to Reduce STDs in ER Drug Users

NCT01379599
View directory record Official record
Conditions
Sexually Transmitted Infection
Interventions
brief motivation intervention
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 54 Years
Enrollment
1,030 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Sep 16, 2026, 10:21 PM EDT