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ClinicalTrials.gov public records Last synced Oct 20, 2026, 9:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 1,555 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Method Comparison Clear all
Completed No phase listed Observational

OPTiMASK: Comparison of Pre-oxygenation With Standard Face Mask Combined With High Flow Nasal Oxygen With Pre-oxygenation With Standard Face Mask Alone

NCT05495841
View directory record Official record
Conditions
Surgery
Interventions
Pre-oxygenation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 20, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MicroRNAs as Biomarkers in First Episode Schizophrenia

NCT07703670
View directory record Official record
Conditions
Schizophrenia Disorder, Schizophreniform Disorder, Schizoaffective Disorder, Psychosis Not Otherwise Specified (NOS)
Interventions
Plasma NDE miRNA Sequencing, Whole Genome Sequencing
Diagnostic Test · Genetic
Lead sponsor
Northwell Health
Other
Eligibility
15 Years to 40 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Terminated Not applicable Interventional

Randomized Sizing and Hemodynamic Study Mitroflow vs. Magna

NCT00705913
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
Mitroflow Aortic Pericardial Heart Valve (CarboMedics), Carpentier-Edwards Magna Tissue Valve
Device
Lead sponsor
Sorin Group USA, Inc.
Industry
Eligibility
18 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
10
States / cities
San Diego, California • Tampa, Florida • Kansas City, Kansas + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2012 · Synced Oct 20, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional

Vestibulectomy Surgical Techniques Comparison Study

NCT05343182
View directory record Official record
Conditions
Vulvar Pain, Vulvodynia
Interventions
Modified Technique, Traditional Technique
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Brain Function Monitoring During Surgery

NCT06619730
View directory record Official record
Conditions
Surgery
Interventions
Sedline Brain Function Monitor
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

NCT04293341
View directory record Official record
Conditions
Major Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder and Agoraphobia
Interventions
Transdiagnostic Behavior Therapy, Cognitive Processing Therapy for PTSD, Cognitive Behavioral Therapy for MDD, Cognitive Behavioral Therapy for Panic Disorder
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Phase 3 Interventional

Multidisciplinary Approach to Reduce Injury and Alcohol

NCT00428181
View directory record Official record
Conditions
Drinking Behavior, Injury Recidivism
Interventions
Brief alcohol intervention, Brief alcohol intervention plus booster
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
605 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
Austin, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2012 · Synced Oct 20, 2026, 9:02 AM EDT
Completed No phase listed Observational

Robotic-assisted and Laparoscopic Right Colectomy Study - Intracorporeal vs. Extracorporeal Anastomoses

NCT03312569
View directory record Official record
Conditions
Benign Right Colon Disease, Malignant Right Colon Disease
Interventions
Right Colectomy with Intracorporeal Anastomosis, Right Colectomy with Extracorporeal Anastomosis
Procedure
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
Irvine, California • Ann Arbor, Michigan • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Phase 3 Interventional Results available

High Dose CVVHDF Compared to Standard Dose CVVHDF

NCT00561431
View directory record Official record
Conditions
Acute Renal Failure
Interventions
Standard dose of dialysis, High dose of dialysis
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 20, 2026, 9:02 AM EDT
Completed No phase listed Observational

Biomarkers in Tissue Samples From Young Patients With Liver Cancer

NCT01336881
View directory record Official record
Conditions
Childhood Hepatoblastoma, Stage I Childhood Liver Cancer, Stage II Childhood Liver Cancer, Stage III Childhood Liver Cancer, Stage IV Childhood Liver Cancer
Interventions
RNA analysis, gene expression analysis, microarray analysis, nucleic acid sequencing, diagnostic laboratory biomarker analysis
Genetic · Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 16 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Monrovia, California
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Oct 20, 2026, 9:02 AM EDT
Recruiting Phase 2 Interventional

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

NCT05112601
View directory record Official record
Conditions
Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Mucinous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Endometrioid Adenocarcinoma, Recurrent Endometrial Carcinoma
Interventions
Biospecimen Collection, Computed Tomography, Ipilimumab, Magnetic Resonance Imaging, Nivolumab
Procedure · Biological
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
138
States / cities
Birmingham, Alabama • Athens, Georgia • Augusta, Georgia + 107 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

In Vitro Maturation (IVM) of Human Oocytes

NCT01550861
View directory record Official record
Conditions
Infertility
Interventions
in vitro maturation, Polar Body Biopsy with preimplantation genetic screening
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
25 Years to 42 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 20, 2026, 9:02 AM EDT
Not yet recruiting Phase 4 Interventional

Rocklatan Retinal Perfusion OCT Study

NCT07174401
View directory record Official record
Conditions
Glaucoma
Interventions
Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months., Two optical coherence tomography (OCT) devices will be used to assess blood flow changes.
Drug · Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Over-the-counter (OTC) Labels for Older Adults

NCT04345731
View directory record Official record
Conditions
Adverse Drug Event
Interventions
Over the counter drug labels
Other
Lead sponsor
Michigan State University
Other
Eligibility
65 Years to 110 Years
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Not applicable Interventional

Advanced Heart Care at Home

NCT03724695
View directory record Official record
Conditions
Palliative Care, Heart Failure, Health Care Utilization, Quality Improvement
Interventions
Clinician nudge or opt out approach for AHCAH liaison visit
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
709 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Terminated Not applicable Interventional

Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in Detecting Colon Cancer

NCT00016029
View directory record Official record
Conditions
Colorectal Cancer
Interventions
screening questionnaire administration, barium enema injection, computed tomography, computed tomography colonography, diagnostic colonoscopy, screening colonoscopy
Other · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
775 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
14
States / cities
La Jolla, California • San Francisco, California • Vero Beach, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2013 · Synced Oct 20, 2026, 9:02 AM EDT
Active, not recruiting Not applicable Interventional

MOTIV BTK Randomized Controlled Trial

NCT05406622
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
MOTIV Sirolimus-Eluting Bioresorbable Scaffold, Percutaneous Transluminal Angioplasty (PTA) Device
Device
Lead sponsor
REVA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
25
States / cities
El Centro, California • Fremont, California • St. Helena, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

PET-Enabled Dual-Energy CT in Multiple Myeloma

NCT07646873
View directory record Official record
Conditions
Multiple Myeloma (MM)
Interventions
PET-enabled dual-energy CT imaging, X-ray dual-energy CT imaging
Diagnostic Test
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Not applicable Interventional

The DETECT HCV Screening Trial

NCT04003454
View directory record Official record
Conditions
Hepatitis C
Interventions
HCV Screening
Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
147,533 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
Denver, Colorado • Baltimore, Maryland • Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Copper IUD Treatment Observation Study

NCT02519231
View directory record Official record
Conditions
Menorrhagia
Interventions
Naproxen, Placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
5
States / cities
Chicago, Illinois • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 20, 2026, 9:02 AM EDT
Completed Not applicable Interventional Results available

Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation

NCT01108237
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
TruMatch™ Personalized Solutions, Total Knee Arthroplasty with Conventional Instrumentation.
Other · Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
18 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
4
States / cities
Baltimore, Maryland • Saint Paul, Minnesota • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Oct 20, 2026, 9:02 AM EDT
Recruiting Phase 2 Interventional

Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)

NCT07313241
View directory record Official record
Conditions
Prostate Cancer
Interventions
Prostate Fossa Radiotherapy, Pelvic nodal Radiotherapy, Androgen Deprivation Therapy (ADT)
Radiation · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 20, 2026, 9:02 AM EDT
Withdrawn No phase listed Observational

Thoracic Endovascular Repair Versus Open Surgery for Blunt Injury

NCT01852773
View directory record Official record
Conditions
Blunt Injury
Interventions
Open repair of thoracic aorta injury, TEVAR
Procedure
Lead sponsor
Scripps Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2016 · Synced Oct 20, 2026, 9:02 AM EDT
Recruiting Not applicable Interventional

The Recovery in Stroke Using PAP Study

NCT04130503
View directory record Official record
Conditions
Ischemic Stroke, Obstructive Sleep Apnea
Interventions
PAP, HLE
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 20, 2026, 9:02 AM EDT