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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:18 AM EDT

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Showing 25–48 of 72 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome analysis Clear all
Recruiting No phase listed Observational

Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome

NCT05982795
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Nasal endoscopy with microbiome swab and mucus collection through filter paper and sponge, Olfactory Function Testing, Survey Completion
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 19, 2026, 10:18 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers

ARGONAUT: Stool and Blood Sample Bank for Cancer Patients

NCT04638751
View directory record Official record
Conditions
Non-small Cell Lung Cancer, Colorectal Cancer, Triple Negative Breast Cancer, Pancreas Cancer
Interventions
Immunotherapy, Chemotherapy, CRC surgical resection, Colonoscopy
Drug · Procedure
Lead sponsor
Persephone Biosciences
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
10
States / cities
Orange, California • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry

NCT05196061
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Questionnaire, Stool sample, Skin swab, Oral rinse
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lean and Obese: Dietary Inflammation

NCT05327868
View directory record Official record
Conditions
Obesity, Inflammation, Dietary Fat
Interventions
Low Fat Diet (LFD), High Fat Diet (HFD)
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years to 79 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Completed Not applicable Interventional

The Effect of Almonds on Facial Aesthetics and Modulation of the Microbiome and Lipidome

NCT03729700
View directory record Official record
Conditions
Wrinkle
Interventions
Almond
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 19, 2026, 10:18 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Mechanisms of Hypoglycemia in Patients Without Diabetes

NCT04428723
View directory record Official record
Conditions
Hypoglycemia
Interventions
Entry of demographic and medical history data into a deidentified database, Blood sample for DNA analysis, Stool sample for microbiome analysis, Mixed meal tolerance test, Continuous glucose monitoring, activity monitor
Other · Genetic · Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Longitudinal Analysis of the Vaginal Microbiome

NCT05383326
View directory record Official record
Conditions
Vaginal Microbiome
Interventions
Not listed
Lead sponsor
Viome
Industry
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Oct 19, 2026, 10:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Analysis of MicroBial Metabolites After Eating Refined Food

NCT04308473
View directory record Official record
Conditions
Dietary Habits
Interventions
Ultra-processed Food Meal, Whole Food Meal
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Novel Mechanisms and Approaches to Treat Neonatal Sepsis

NCT02554630
View directory record Official record
Conditions
Complication of Prematurity, Immunologic Deficiency Syndromes
Interventions
Adjuvant, Blood Collection
Other
Lead sponsor
University of Florida
Other
Eligibility
Up to 55 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 19, 2026, 10:18 AM EDT
Terminated Not applicable Interventional Results available

"Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures

NCT05523154
View directory record Official record
Conditions
Benign Pancreatic Neoplasm, Malignant Pancreatic Neoplasm
Interventions
Biospecimen Collection, Laboratory Procedure, Nanopore Sequencing
Procedure · Other · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Oct 19, 2026, 10:18 AM EDT
Not listed No phase listed Observational

Gut Microbiome and Ventricular Arrhythmias

NCT04466072
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Gut Microbiome
Interventions
Stool test for microbial analysis
Diagnostic Test
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Oct 19, 2026, 10:18 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease

NCT06215222
View directory record Official record
Conditions
IBS - Irritable Bowel Syndrome, Healthy, Functional Bloating, Functional Gastrointestinal Disorders
Interventions
Microbiota Sampling
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 19, 2026, 10:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Gut Organoid and Microbiome Interactions in Hypertension

NCT04497727
View directory record Official record
Conditions
Gut Inflammation, Hypertension
Interventions
Gene Expression
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 19, 2026, 10:18 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)

NCT05568420
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 49 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs

NCT05666778
View directory record Official record
Conditions
Bacterial Vaginosis, Vaginal Microbiome, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginitis
Interventions
Menstrual Cup
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
15 Years to 35 Years · Female only
Enrollment
408 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Infant Restore: Efficacy of Microbiome Analysis and Education

NCT06424691
View directory record Official record
Conditions
Microbiota, Eczema, Microbiome, Gut Microbiome
Interventions
Tailored Recommendations, Consult Call, Email Series
Dietary Supplement · Behavioral
Lead sponsor
Seeding Inc
Industry
Eligibility
0 Months to 3 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fredericksburg, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 19, 2026, 10:18 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

OAB and the Microbiome

NCT04831801
View directory record Official record
Conditions
Overactive Bladder, Urgency-frequency Syndrome
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Fort Lauderdale, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 19, 2026, 10:18 AM EDT
Enrolling by invitation Not applicable Interventional

Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

NCT06406751
View directory record Official record
Conditions
Dental Prosthesis
Interventions
MI Paste
Device
Lead sponsor
University of Iowa
Other
Eligibility
65 Years to 105 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 19, 2026, 10:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

GI Tract Biomarkers in Infants With Different Diets

NCT03751137
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Not listed
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Weeks to 3 Months
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 19, 2026, 10:18 AM EDT
Completed No phase listed Observational

Analysis of Inflammation and Microbiome in Patients With Sinusitis and Asthma

NCT02548598
View directory record Official record
Conditions
Asthma, Chronic Rhinosinusitis
Interventions
Endoscopic sinus surgery
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 19, 2026, 10:18 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

High-Resolution Measurements of Diet-Microbiome Interactions

NCT07856823
View directory record Official record
Conditions
IBS (Irritable Bowel Syndrome)
Interventions
Inulin, Low-fiber control breakfast shake, Atmo Gas-Sensing Capsule, CapScan Regional Fluid-Sampling Capsule
Dietary Supplement · Other · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Recruiting No phase listed Observational

Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)

NCT06396533
View directory record Official record
Conditions
Urothelial Carcinoma, Muscle Invasive Bladder Urothelial Carcinoma, Non-Muscle Invasive Bladder Urothelial Carcinoma
Interventions
Not listed
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Omaha, Nebraska • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 19, 2026, 10:18 AM EDT
Enrolling by invitation Not applicable Interventional

Assessing Microbiome in Primary Anterior Cervical Fusion Patients

NCT07877766
View directory record Official record
Conditions
Cervical Stenosis, Myelopathy, Cervical Spondylosis With Myelopathy, Degenerative Disc Disease, Radiculopathy
Interventions
Primary Anterior Cervical Discectomy Procedures
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 19, 2026, 10:18 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

NCT05821309
View directory record Official record
Conditions
Constipation
Interventions
PEG 3350, PEG-3350 with electrolytes, Glycerin
Drug
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 18 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 19, 2026, 10:18 AM EDT