- Conditions
- Moderate to Advanced Chronic Periodontitis
- Interventions
- locally-applied minocycline HCl (1 mg), scaling and root planing (Sc/RP)
- Drug · Procedure
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 2
- States / cities
- Lincoln, Nebraska • Omaha, Nebraska
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Showing 1–10
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- Conditions
- SRP, Minocycline HCl Microspheres, Biomarkers
- Interventions
- minocycline HCl microspheres
- Drug
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Peri-Implantitis
- Interventions
- Minocycline HCl Microspheres
- Drug
- Lead sponsor
- OraPharma
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 208 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 10
- States / cities
- Baltimore, Maryland • Boston, Massachusetts • Ann Arbor, Michigan + 7 more
- Conditions
- Periodontitis
- Interventions
- Minocycline HCl microspheres
- Drug
- Lead sponsor
- OraPharma
- Industry
- Eligibility
- 25 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Periodontitis
- Interventions
- Minocycline HCL Microspheres
- Drug
- Lead sponsor
- OraPharma
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 128 participants
- Timeline
- Started 2004
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 2 more
- Conditions
- Periodontitis, Diabetes Mellitus Type 2
- Interventions
- local antibiotic application of topical minocycline, Scaling and Root Planing
- Drug · Procedure
- Lead sponsor
- Case Western Reserve University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Periodontitis
- Interventions
- Minocycline HCl
- Drug
- Lead sponsor
- OraPharma
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 4
- States / cities
- Aurora, Colorado • Ann Arbor, Michigan • Hazlet, New Jersey + 1 more
- Conditions
- SRP, Minocycline HCl Microspheres, Biomarkers
- Interventions
- Measurement of Biomarkers
- Procedure
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Peri-Implantitis
- Interventions
- Minocycline HCl Microspheres
- Drug
- Lead sponsor
- OraPharma
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 215 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Gainsville, Florida • Augusta, Georgia + 6 more
- Conditions
- Periodontitis
- Interventions
- SRP + MM, Scaling and Root Planing (SRP)
- Procedure
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia