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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:39 PM EDT

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Showing 25–48 of 1,285 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Model 2 Clear all
Suspended Phase 1 Interventional

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

NCT05400122
View directory record Official record
Conditions
Colorectal Cancer, Hematologic Malignancy, Rectum Cancer, Acute Myeloid Leukemia, Myelodysplastic Syndromes, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Hodgkin Lymphoma, Non Hodgkin Lymphoma, Myeloproliferative Syndrome, Plasma Cell Myeloma, Gastric Cancer, Esophageal Cancer, Esophagus Cancer, Gastric Cancer, Metastatic, Unresectable Esophageal Cancer, Metastatic Esophageal Cancer
Interventions
Vactosertib, Fludarabine Phosphate, Cyclophosphamide, IL-2, Natural Killer Cells
Drug
Lead sponsor
David Wald
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Not listed Not applicable Interventional

Examining the Feasibility of a Mobile Mental Health Application in Psychotherapy

NCT04200170
View directory record Official record
Conditions
Mental Health Wellness 1, Depression
Interventions
Rose
Device
Lead sponsor
Ask Rose
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 30, 2026, 2:39 PM EDT
Recruiting Phase 3 Interventional

Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

NCT07144345
View directory record Official record
Conditions
Actinic Keratosis
Interventions
Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%, Vehicle containing excipients only (VEH) without active ingredient, Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E
Drug · Other · Device
Lead sponsor
Sun Pharmaceutical Industries, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
10
States / cities
Fremont, California • Aventura, Florida • Rolling Meadows, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ecological Momentary Assessment and Text Message Intervention for Stress Management

NCT04907942
View directory record Official record
Conditions
Stress, Psychological, Loneliness, Covid19, Stress
Interventions
EMA + EMA and FACE Stress, EMA Alone
Other
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?

NCT02918851
View directory record Official record
Conditions
Healthy
Interventions
Transfusion of 7-day stored red blood cells, Transfusion of 28-day stored red blood cells, Transfusion of 42-day stored red blood cells
Biological
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 40 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Compass for Care: A Theory-driven Mobile Solution to Promote Well-being Among Caregivers of Individuals With ADRD

NCT06249139
View directory record Official record
Conditions
Dementia, Mental Health
Interventions
Compass for Care (Well-being intervention), Compass for Care (Safety intervention)
Behavioral
Lead sponsor
Pro-Change Behavior Systems
Other
Eligibility
18 Years and older
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Narragansett, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional Results available

Stroke Telemedicine Outpatient Prevention Program for Blood Pressure Reduction

NCT03923790
View directory record Official record
Conditions
Stroke Prevention, Blood Pressure, Telemedicine, Psychosocial Impairment
Interventions
Educational Packet, Phone call at 72 hours by discharge nurse navigator, Telehealth visit at 7 days, 1 month, 3 months, and 5 months after discharge, Educational messages every other week, BP monitoring by QardioARM with periodic transmission of BP data
Behavioral · Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Aerobic Exercise and Aphasia Treatment

NCT02999360
View directory record Official record
Conditions
Aphasia
Interventions
Language therapy, Background Music, Aerobic Exercise
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 30, 2026, 2:39 PM EDT
Recruiting Phase 2 Interventional

Mosunetuzumab in Patients With Newly Diagnosed Extranodal Marginal Zone Lymphoma

NCT06569680
View directory record Official record
Conditions
Extranodal Marginal Zone Lymphoma
Interventions
Mosunetuzumab
Drug
Lead sponsor
Izidore Lossos, MD
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Terminated Phase 1 Interventional

Diazoxide Suppression Test P&F Study

NCT06606327
View directory record Official record
Conditions
Insulin Resistance, Hyperinsulinemia, Obesity
Interventions
Diazoxide, 3 mg/kg per dose
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Suspended Not applicable Interventional

Insulin Sensitivity in Men With the Metabolic Syndrome

NCT00433173
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
intravenous glucose tolerance test, testosterone, anastrozole, goserelin acetate implant, aerobic capacity (VO2 Max), MRI, muscle biopsy, measurement of resting metabolic rate (energy expenditure), Dual energy x-ray absorptiometry, Fasting oral glucose tolerance test
Procedure · Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
50 Years to 75 Years · Male only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2010 · Synced Oct 30, 2026, 2:39 PM EDT
Recruiting Not applicable Interventional

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

NCT06957067
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Study Comparing Two Different Methods of Treating Periodontal Disease

NCT00127244
View directory record Official record
Conditions
Periodontal Diseases
Interventions
Periodontal Treatment
Procedure
Lead sponsor
The Forsyth Institute
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2010 · Synced Oct 30, 2026, 2:39 PM EDT
Active, not recruiting Not applicable Interventional

Alcohol Screening and Preoperative Intervention Research Study - 2

NCT05783635
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Enhanced Usual Care (pre-operative), Preoperative Virtual Health Coaching, Usual surgical care (post-operative), Postoperative Virtual Health Coaching, On-Track (Post-operative)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 75 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Phase 3 Interventional

GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma

NCT01052558
View directory record Official record
Conditions
Glaucoma
Interventions
iStent Inject (GTS400), Cataract Surgery
Device · Procedure
Lead sponsor
Glaukos Corporation
Industry
Eligibility
18 Years to 90 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
22
States / cities
Rogers, Arkansas • Petaluma, California • Parker, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated May 19, 2015 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adapting a Parenting Intervention to Promote Healthy Screen Time Habits in Young Children With Behavior Problems

NCT05287685
View directory record Official record
Conditions
Behavior Problem, Parenting
Interventions
Screen media adapted School Readiness Parenting Program, School Readiness Parenting Program
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
54 Months to 66 Months
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 30, 2026, 2:39 PM EDT
Recruiting Phase 2 Interventional

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

NCT07201519
View directory record Official record
Conditions
Colorectal Cancer Metastatic, Intrahepatic Cholangiocarcinoma
Interventions
Hepatic Artery Infusion Pump (HAIP), Standard Treatment, Community Treatment, Systemic Chemotherapy Standard of Care, Standard Of Care targeting driver mutations
Device · Procedure · Drug
Lead sponsor
Michael J Cavnar, MD
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Maintaining HIV Prevention Gains in Female Adolescents

NCT00161343
View directory record Official record
Conditions
HIV Infection, Sexually Transmitted Diseases
Interventions
Health Improvement Project for Teens on HIV Prevention
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
15 Years to 19 Years · Female only
Enrollment
640 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2012 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional Results available

Program ACTIVE II: Behavioral Depression Treatment for Type 2 Diabetes

NCT03371940
View directory record Official record
Conditions
Type2 Diabetes, Depression
Interventions
Program ACTIVE Exercise, Program ACTIVE CBT, Program ACTIVE, Usual Care - No intervention
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
3
States / cities
Indianapolis, Indiana • Athens, Ohio • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Oct 30, 2026, 2:39 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Evaluation of the Walk With Ease Program for Fall Prevention

NCT05693025
View directory record Official record
Conditions
Exercise, Frailty, Arthritis, Accidental Falls
Interventions
Group Exercise, Behavioral Training
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Oct 30, 2026, 2:39 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Adaptation and Evaluation of RESTORE

NCT07104474
View directory record Official record
Conditions
Nurse, Burnout, Healthcare Workers
Interventions
RESTORE
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 30, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Light Therapy for Depression in Adolescent Outpatients

NCT05823090
View directory record Official record
Conditions
Depression, Adolescent - Emotional Problem
Interventions
light box (Carex DayLight Classic Model)
Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
12 Years to 18 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 30, 2026, 2:39 PM EDT
Active, not recruiting Not applicable Interventional

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

NCT06216574
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Internet-based Intervention
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
236
States / cities
Phoenix, Arizona • Fort Smith, Arkansas • Antioch, California + 199 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 30, 2026, 2:39 PM EDT