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ClinicalTrials.gov public records Last synced Nov 9, 2026, 7:32 PM EST

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Showing 25–44 of 44 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Monofocal Intraocular Lens Clear all

Conditions: Aphakia
Interventions: Clareon Vivity/Vivity Toric Extended Vision IOL, Clareon Monofocal/Clareon Toric IOL; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 7
States / cities: Torrance, California • Fort Collins, Colorado • Bloomfield Hills, Michigan + 4 more

Conditions: Cataract
Interventions: Clareon monofocal Intraocular lens (toric and non-toric models); Device
Lead sponsor: Eye Consultants of Atlanta; Other
Eligibility: 45 Years and older
Enrollment: 34 participants
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Cataract
Interventions: Clareon TruPlus, Clareon monofocal; Device
Lead sponsor: Berkeley Eye Center; Other
Eligibility: 22 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Cataract, Presbyopia
Interventions: Neutral Aspheric Monofocal IOL, Negative Aspheric Monofocal IOL; Device
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 95 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Cataract
Interventions: non-toric intraocular lens, toric intraocular lens; Device
Lead sponsor: Abbott Medical Optics; Industry
Eligibility: 22 Years and older
Enrollment: 365 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 44
States / cities: Dothan, Alabama • Chandler, Arizona • Tucson, Arizona + 37 more

Conditions: Pseudophakia
Interventions: Not listed
Lead sponsor: Innovative Medical; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Cataract, Glaucoma, Ocular Hypertension
Interventions: Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%, Commercial IOL; Drug · Device
Lead sponsor: SpyGlass Pharma, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Cataract
Interventions: Crystalens AO, SoftPort LI61AO; Device
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 40 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Irvine, California

Conditions: Cataract
Interventions: TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00; Device
Lead sponsor: Abbott Medical Optics; Industry
Eligibility: 22 Years to 99 Years
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 15
States / cities: Rogers, Arkansas • Bakersfield, California • Boynton Beach, Florida + 12 more

Conditions: Cataracts, Astigmatism
Interventions: SN6AT6 Intraocular Lens, SN6AT7 Intraocular Lens, SN6AT8 Intraocular Lens, SN6AT9 Intraocular Lens, SN60WF Intraocular Lens; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 21 Years and older
Enrollment: 477 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Cataract Senile
Interventions: Cataract Surgery; Device
Lead sponsor: Carl Zeiss Meditec, Inc.; Industry
Eligibility: 22 Years to 100 Years
Enrollment: 284 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 14
States / cities: Beverly Hills, California • Northridge, California • Orange, California + 11 more

Conditions: Cataract, Corneal Astigmatism
Interventions: RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery; Device · Procedure
Lead sponsor: Rayner Intraocular Lenses Limited; Industry
Eligibility: 22 Years and older
Enrollment: 274 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 9
States / cities: Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more

Conditions: Cataract
Interventions: enVista Beyond EY (EDF) IOL, enVista MX60E monofocal IOL; Device
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 22 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 16
States / cities: Dothan, Alabama • Northridge, California • Alexandria, Minnesota + 12 more

Conditions: Cataract
Interventions: modified light transmission intraocular lens, monofocal acrylic intraocular lens; Device
Lead sponsor: Abbott Medical Optics; Industry
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 11
States / cities: Scottsdale, Arizona • Rogers, Arkansas • New Haven, Connecticut + 8 more

Conditions: Cataract
Interventions: LAL (Light Adjustable Lens) and Light Deliver Device (LDD), Monofocal control IOL; Device
Lead sponsor: Calhoun Vision, Inc.; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 17
States / cities: Fayetteville, Arkansas • Los Angeles, California • Torrance, California + 14 more

Conditions: Primary Open Angle Glaucoma
Interventions: Hydrus Microstent, Cataract surgery, Monofocal IOL; Device · Procedure
Lead sponsor: Alcon Research; Industry
Eligibility: 45 Years and older
Enrollment: 545 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 22
States / cities: Irvine, California • Sacramento, California • Loveland, Colorado + 19 more

Conditions: Cataract
Interventions: ARGOS Biometer; Device
Lead sponsor: Vance Thompson Vision; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Cataract, Presbyopia
Interventions: Extended Vision IOL, Neutral Aspheric Monofocal IOL; Device
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 95 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Cataract
Interventions: CT LUCIA 621P; Device
Lead sponsor: Carl Zeiss Meditec AG; Industry
Eligibility: 50 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 3
States / cities: Indianapolis, Indiana • Lexington, Kentucky • Hershey, Pennsylvania

Conditions: Cataract, Glaucoma, Ocular Hypertension
Interventions: Bimatoprost Implant System (High Dose), Bimatoprost Implant System (Low Dose), Timolol Maleate Ophthalmic Solution, 0.5%, Commercially Available Aspheric Monofocal Non-Yellow Chromophore IOL, SpyGlass IOL; Drug · Device
Lead sponsor: SpyGlass Pharma, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Glendale, Arizona

Search by objective public record fields.

Evaluation of Clareon Vivity/Vivity Toric

Visual Outcomes and Patient Satisfaction With Implantation of the Clareon Monofocal IOL With the New Clareon Manual Monarch IV IOL Delivery System

A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects

MULTICENTER, DOUBLE-ARM, PATIENT AND ASSESSOR-MASKED, PROSPECTIVE, RANDOMIZED CLINICAL TRIAL TO COMPARE VISUAL PERFORMANCE OF NEGATIVE AND NEUTRAL ASPHERIC MONOFOCAL INTRAOCULAR LENSES

Post-Approval Study of the Tecnis® Toric IOL

An Open-Label Evaluation of Degree of Accommodation in Pseudophakic Patients Bilaterally Implanted With Monofocal Intraocular Lenses

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

Accommodation Measurements After Bilateral Implantation of an Aspheric Accommodating Lens and Monofocal Aspheric Lenses

Clinical Investigation of a New Intraocular Lens

Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9

AT ELANA 841P Posterior Chamber Intraocular Lens for Correction of Aphakia Following Cataract Removal

Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism

Study to Evaluate the Safety and Effectiveness of the enVista® Beyond (EY) EDF Intraocular Lens in Subjects Undergoing Cataract Extraction

Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)

Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism

Hydrus® Microstent New Enrollment Post-Approval Study

Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study

Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses

Evaluation of a Monofocal Intraocular Lens

Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution