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Showing 25–41 of 17 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Monofocal Intraocular Lens Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)

NCT00747227
View directory record Official record
Conditions
Cataract
Interventions
modified light transmission intraocular lens, monofocal acrylic intraocular lens
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
11
States / cities
Scottsdale, Arizona • Rogers, Arkansas • New Haven, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2011 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses

NCT04591054
View directory record Official record
Conditions
Cataract, Presbyopia
Interventions
Extended Vision IOL, Neutral Aspheric Monofocal IOL
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 21, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Comparison of Visual Outcomes With Mini-Monovision Between a Monofocal and an Adjustable Intraocular Lens

NCT06122103
View directory record Official record
Conditions
Cataract
Interventions
Clareon Monofocal, Light-Adjustable Lens
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 21, 2026, 4:41 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution

NCT06120842
View directory record Official record
Conditions
Cataract, Glaucoma, Ocular Hypertension
Interventions
Bimatoprost Implant System (High Dose), Bimatoprost Implant System (Low Dose), Timolol Maleate Ophthalmic Solution, 0.5%, Commercially Available Aspheric Monofocal Non-Yellow Chromophore IOL, SpyGlass IOL
Drug · Device
Lead sponsor
SpyGlass Pharma, Inc.
Industry
Eligibility
22 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Glendale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 21, 2026, 4:41 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study

NCT01191515
View directory record Official record
Conditions
Patients Implanted With Monofocal Intraocular Lens
Interventions
Monofocal Intraocular Lenses
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Williamsburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Sep 21, 2026, 4:41 PM EDT
Recruiting Phase 3 Interventional

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

NCT07218796
View directory record Official record
Conditions
Cataract, Glaucoma, Ocular Hypertension
Interventions
Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%, Commercial IOL
Drug · Device
Lead sponsor
SpyGlass Pharma, Inc.
Industry
Eligibility
22 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Clinical Investigation of a New Intraocular Lens

NCT02203721
View directory record Official record
Conditions
Cataract
Interventions
TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
22 Years to 99 Years
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
15
States / cities
Rogers, Arkansas • Bakersfield, California • Boynton Beach, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Results available

Contralateral ReSTOR / Monofocal or Phakic Eye

NCT00731640
View directory record Official record
Conditions
Cataracts
Interventions
ReSTOR
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2010 · Synced Sep 21, 2026, 4:41 PM EDT
Completed No phase listed Observational Results available

Visual Outcomes and Patient Satisfaction With Implantation of the Clareon Monofocal IOL With the New Clareon Manual Monarch IV IOL Delivery System

NCT05526781
View directory record Official record
Conditions
Cataract
Interventions
Clareon monofocal Intraocular lens (toric and non-toric models)
Device
Lead sponsor
Eye Consultants of Atlanta
Other
Eligibility
45 Years and older
Enrollment
34 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Post-Approval Study of the Tecnis® Toric IOL

NCT02566083
View directory record Official record
Conditions
Cataract
Interventions
non-toric intraocular lens, toric intraocular lens
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
22 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
44
States / cities
Dothan, Alabama • Chandler, Arizona • Tucson, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism

NCT01496066
View directory record Official record
Conditions
Cataract
Interventions
LAL (Light Adjustable Lens) and Light Deliver Device (LDD), Monofocal control IOL
Device
Lead sponsor
Calhoun Vision, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
17
States / cities
Fayetteville, Arkansas • Los Angeles, California • Torrance, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluation of a Monofocal Intraocular Lens

NCT06428955
View directory record Official record
Conditions
Cataract
Interventions
CT LUCIA 621P
Device
Lead sponsor
Carl Zeiss Meditec AG
Industry
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Lexington, Kentucky • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 21, 2026, 4:41 PM EDT
Completed No phase listed Observational

A Real-World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses

NCT05799950
View directory record Official record
Conditions
Aphakia
Interventions
AcrySof single-piece IOL, AcrySof multi-piece IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
Not listed
Enrollment
138 participants
Timeline
2023 – 2025
U.S. locations
6
States / cities
Burbank, California • Jacksonville, Florida • Rock Island, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Sep 21, 2026, 4:41 PM EDT
Completed No phase listed Observational

Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study

NCT07129980
View directory record Official record
Conditions
Cataract
Interventions
ARGOS Biometer
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)

NCT03274986
View directory record Official record
Conditions
Cataract
Interventions
ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
11
States / cities
Birmingham, Alabama • Fort Collins, Colorado • Bradenton, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Sep 21, 2026, 4:41 PM EDT
Completed No phase listed Observational

Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9

NCT01601665
View directory record Official record
Conditions
Cataracts, Astigmatism
Interventions
SN6AT6 Intraocular Lens, SN6AT7 Intraocular Lens, SN6AT8 Intraocular Lens, SN6AT9 Intraocular Lens, SN60WF Intraocular Lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional

AT ELANA 841P Posterior Chamber Intraocular Lens for Correction of Aphakia Following Cataract Removal

NCT06264232
View directory record Official record
Conditions
Cataract Senile
Interventions
Cataract Surgery
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years to 100 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
14
States / cities
Beverly Hills, California • Northridge, California • Orange, California + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 21, 2026, 4:41 PM EDT