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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:18 PM EDT

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Showing 97–120 of 646 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Muscle Strength Clear all
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy

NCT07687745
View directory record Official record
Conditions
Hypertension Disorders in Pregnancy, Blood Pressure Measurement in Pregnancy, Inspiratory Strength Training (IST), Pregnancy
Interventions
Exercise at 15% PI max, Exercise at 50% PI max
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Not applicable Interventional

Blood Flow Restriction to Improve Muscle Strength After ACL Injury

NCT03141801
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training, Eccentric Exercise with BLAST Leg Press System, Concentric Exercise with BLAST Leg Press System
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Not applicable Interventional

Enhancing Resilience in Young Stroke Survivors With Res-ET

NCT05348044
View directory record Official record
Conditions
Resilience, Stroke
Interventions
Res-ET intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 19, 2026, 4:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Exercise Mode on Cardiac Fat and Function

NCT03297333
View directory record Official record
Conditions
Obesity
Interventions
Resistance training, Aerobic interval training
Other
Lead sponsor
Southern Illinois University Edwardsville
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edwardsville, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Not applicable Interventional

NMES to Improve Hip Abductor Strength and Balance

NCT02992275
View directory record Official record
Conditions
Postural Balance
Interventions
Neuromuscular electrical stimulation (NMES), Multi-Modality Balance Intervention (MMBI)
Other
Lead sponsor
Baltimore VA Medical Center
Federal
Eligibility
60 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 19, 2026, 4:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Scapular and Cervical Neuromuscular Control Deficits in Musicians With and Without Playing Injuries.

NCT02267395
View directory record Official record
Conditions
Playing Related Musculoskeletal Disorders
Interventions
(1) cranio-cervical flexion test;, (2) scapular dyskinesis test, (3) deep neck flexor endurance test.
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Franklin, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 1, 2016 · Synced Oct 19, 2026, 4:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure

NCT04848675
View directory record Official record
Conditions
Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
Inspiratory muscle strength training, Brisk walking
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Phase 1 Interventional

Project FARMS: Fall Risk Reduction in Multiple Sclerosis

NCT01837017
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Home-based Exercise
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
50 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 25, 2014 · Synced Oct 19, 2026, 4:18 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

EIMD Mechanisms Causing Force Loss

NCT02125643
View directory record Official record
Conditions
Healthy
Interventions
Caffeine, Flour
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 35 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Norman, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Improving the Recovery and Outcome Every Day After the ICU

NCT03095417
View directory record Official record
Conditions
Delirium, Alzheimer Disease
Interventions
Physical Exercise Intervention, Cognitive Training Intervention, Stretching Control, Cognitive Control
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
6
States / cities
Avon, Indiana • Carmel, Indiana • Fishers, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 19, 2026, 4:18 PM EDT
Terminated Early Phase 1 Interventional

A Pilot Study of Pyridostigmine in Pompe Disease

NCT02357225
View directory record Official record
Conditions
Pompe Disease
Interventions
Pyridostigmine Bromide
Drug
Lead sponsor
University of Florida
Other
Eligibility
8 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Phase 3 Interventional Results available

Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant

NCT03116997
View directory record Official record
Conditions
Surgery
Interventions
Neostigmine+glycopyrrolate, Sugammadex
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 19, 2026, 4:18 PM EDT
Recruiting Phase 2 Interventional

Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

NCT07020312
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
Interventions
Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 19, 2026, 4:18 PM EDT
Recruiting Not applicable Interventional

Expiratory Muscle Strength Training for Hypernasal Speech in Children

NCT05492266
View directory record Official record
Conditions
Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate, Inadequate Velopharyngeal Closure, Palatopharyngeal Incompetence, Hypernasality
Interventions
Expiratory Muscle Strength Training, Maintenance Training
Device
Lead sponsor
Noel Jabbour
Other
Eligibility
5 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 19, 2026, 4:18 PM EDT
Not listed Not applicable Interventional

Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients

NCT01363102
View directory record Official record
Conditions
Muscle Weakness, Critical Illness, Respiratory Insufficiency
Interventions
SOMS
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 19, 2026, 4:18 PM EDT
Recruiting Not applicable Interventional

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

NCT07324772
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Persistent Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
progressive resistance training, combined aerobic + resistance training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 19, 2026, 4:18 PM EDT
Recruiting Not applicable Interventional

Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD

NCT07059637
View directory record Official record
Conditions
COPD, Emphysema, Sarcopenia
Interventions
Multidisciplinary clinic evaluation, COPD standard of care
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 19, 2026, 4:18 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

NCT02367170
View directory record Official record
Conditions
Sepsis
Interventions
Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
Procedure · Drug · Device + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training and Milk Supplementation

NCT04509297
View directory record Official record
Conditions
Muscular Hypertrophy
Interventions
high protein milk, Placebo
Dietary Supplement
Lead sponsor
Marymount University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Phase 2 Interventional

The Lived Experiences Measured Using Rings Pilot Study

NCT05841979
View directory record Official record
Conditions
Depression, Stress, Sleep, Anxiety
Interventions
Moodlifters, Physical Activity, Nature Experiences
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 25 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 19, 2026, 4:18 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Quadriceps Motor Unit Adaptation to Simulated Knee Injury

NCT06999057
View directory record Official record
Conditions
Muscle Inhibition, Knee Injury Simulation
Interventions
Joint Effusion via 60 mL Sterile Saline, Intra-articular Lidocaine, Sham injection
Device · Drug · Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 19, 2026, 4:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance

NCT05249595
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Transverse Myelitis
Interventions
Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Piloting Prehabilitation Before Abdominal Surgery

NCT03040336
View directory record Official record
Conditions
Frailty
Interventions
Prehabilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 19, 2026, 4:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Mental Effort and Muscle Strength

NCT00059436
View directory record Official record
Conditions
Aging, Muscle Strength
Interventions
Mental effort in muscle strengthening
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
65 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1999
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Oct 19, 2026, 4:18 PM EDT