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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:56 AM EST

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Showing 145–168 of 230 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: N Acetyl Cysteine Clear all

Conditions: Bronchiolitis Acute
Interventions: N-Acetyl Cysteine; Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 1 Week to 2 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Ovarian Cancer, Cognitive Impairment
Interventions: N-Acetyl-Cysteine, Placebo; Drug · Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Orange, California

Conditions: Purpura, Thrombotic Thrombocytopenic, TTP
Interventions: N-Acetylcysteine; Drug
Lead sponsor: Bloodworks; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Tinnitus
Interventions: DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine; Drug
Lead sponsor: Leading Edge Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Ithaca, New York

Conditions: Cocaine-Related Disorders
Interventions: N-Acetylcysteine, Placebo; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Emotional Dysregulation
Interventions: N-Acetyl Cysteine (NAC), Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 6 Years to 12 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2030
U.S. locations: 2
States / cities: Boston, Massachusetts • Cambridge, Massachusetts

Conditions: Neuromuscular Disease
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 7 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Autistic Disorder, Asperger Syndrome, Child Development Disorders, Pervasive
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Indiana University; Other
Eligibility: 4 Years to 12 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Progressive Multiple Sclerosis, Fatigue
Interventions: N-acetyl cysteine, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anosmia
Interventions: N-acetyl cysteine (NAC); Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obesity, Nonalcoholic Fatty Liver Disease, Cardiovascular Disease
Interventions: N-acetyl cysteine 600 mg once/day, N-acetyl cysteine 600mg twice/day, Placebo twice/day; Dietary Supplement · Other
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 7 Years to 18 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Cocaine-Related Disorders
Interventions: N-acetylcysteine, Theta-burst stimulation (TBS); Drug · Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Pulmonary Fibrosis
Interventions: N-acetylcysteine (NAC), Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 35 Years to 85 Years
Enrollment: 264 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 26
States / cities: Birmingham, Alabama • Los Angeles, California • San Francisco, California + 20 more

Conditions: Cocaine Abuse or Dependence, Cocaine Related Disorders
Interventions: Not listed
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Insulin Resistance, Metabolic Syndrome x
Interventions: N-acetylcysteine 20% 4ml, N-acetylcysteine 20% in 4 ml; Drug
Lead sponsor: Midwest Biomedical Research; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Pathological Gambling
Interventions: N-Acetyl Cysteine; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Type 1 Diabetes, Hypoglycemia Unawareness
Interventions: N-acetyl cysteine, Placebo; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Parkinson Disease, Idiopathic Parkinson Disease
Interventions: N acetyl cysteine, [F-18] Fluorodopa Positron Emission Tomography; Dietary Supplement · Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 30 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere, Oxidative Stress
Interventions: N-acetylcysteine, Placebo; Drug · Other
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Everett, Massachusetts

Conditions: Hepatitis C
Interventions: N-acetylcysteine(Mucomyst); Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Retinitis Pigmentosa
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 485 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 24
States / cities: Davis, California • Los Angeles, California • San Francisco, California + 21 more

Conditions: COPD, Chronic Bronchitis
Interventions: N-Acetylcysteine, Placebo; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 40 Years to 85 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Biliary Atresia
Interventions: N-Acetyl cysteine; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 0 Days to 90 Days
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Alcoholism
Interventions: Topiramate and N-Acetyl Cysteine, Topiramate and Placebo; Drug
Lead sponsor: Nassima Ait-Daoud Tiouririne; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Charlottesville, Virginia

Search by objective public record fields.

Nebulized N-Acetyl Cysteine for Bronchiolitis in Inpatient Hospital Use

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

A Pilot Study of N-acetylcysteine in Thrombotic Thrombocytopenia Purpura

DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury

Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1

The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation

Antioxidant Therapy in RYR1-Related Congenital Myopathy

A Study of Oral N-Acetylcysteine in Children With Autism Spectrum Disorders

A Study of Oxidative Pathways in MS Fatigue

NAC Trial for Anosmia

Fatty Liver Disease in Obese Children

Neurocircuit Strategy to Decrease Cocaine Cue Reactivity

Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in Patients With IPF

Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC)

Insulin Resistance Study

An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling

A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes

FDOPA PET and Nutritional Support in Parkinson's Disease

NAC for Attenuation of COVID-19 Symptomatology

Mucomyst for Hepatitis C

Oral N-acetylcysteine for Retinitis Pigmentosa

N-Acetylcysteine for Patients With COPD and Chronic Bronchitis

N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy

Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder