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ClinicalTrials.gov public records Last synced Oct 2, 2026, 3:21 PM EDT

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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Nasal Continuous Positive Airway Pressure (NCPAP) Clear all

Conditions: Respiratory Distress Syndrome
Interventions: Gradual pressure wean; Other
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 26 Weeks to 32 Weeks
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: High flow nasal cannula, Nasal CPAP; Procedure
Lead sponsor: Sharp HealthCare; Other
Eligibility: 23 Weeks to 28 Weeks
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Transient Tachypnea of the Newborn
Interventions: High Flow Nasal Cannula, Bubble Nasal CPAP; Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: Up to 24 Hours
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Respiratory Distress Syndrome
Interventions: Aerosolized lucinactant; Drug
Lead sponsor: Windtree Therapeutics; Industry
Eligibility: 15 Minutes to 30 Minutes
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005
U.S. locations: 1
States / cities: San Diego, California

Conditions: Respiratory Distress Syndrome
Interventions: HHHFNC, NCPAP; Device
Lead sponsor: Sidra Medicine; Other
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Akron, Ohio

Conditions: Respiratory Insufficiency of Prematurity
Interventions: nCPAP, NIPPV; Device
Lead sponsor: McMaster University; Other
Eligibility: Up to 28 Days
Enrollment: 1,011 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 14
States / cities: Washington D.C., District of Columbia • Boston, Massachusetts • Voorhees Township, New Jersey + 6 more

Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: AeroFact, nCPAP; Drug · Other
Lead sponsor: Aerogen Pharma Limited; Industry
Eligibility: 26 Weeks to 31 Weeks
Enrollment: 261 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 37
States / cities: Little Rock, Arkansas • Berkeley, California • Orange, California + 27 more

Conditions: Respiratory Distress, Lung Injury
Interventions: Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Hours to 72 Hours
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Respiratory Distress Syndrome
Interventions: Lucinactant for Inhalation, nCPAP alone; Drug · Device
Lead sponsor: Windtree Therapeutics; Industry
Eligibility: 29 Weeks to 34 Weeks
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 11
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Loma Linda, California + 8 more

Conditions: Respiratory Distress Syndrome, Newborn
Interventions: PS Group, NCPAP Group, ISX Group; Drug · Device
Lead sponsor: Vermont Oxford Network; Network
Eligibility: 26 Weeks to 29 Weeks
Enrollment: 648 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Knee Replacement Surgery
Interventions: Nasal Continuous Positive Airway Pressure (NCPAP); Other
Lead sponsor: Pediatrix; Other
Eligibility: 21 Years to 69 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Wilmington, North Carolina

Conditions: Respiratory Insufficiency
Interventions: Pulmonary Function Testing & esophageal pressure monitoring, Pulmonary function testing and esophageal pressure; Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 2 Days to 6 Months
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Respiratory Distress Syndrome
Interventions: Nasal continuous positive airway pressure (nCPAP), Laryngeal Mask Airway (LMA) to deliver surfactant, Surfactants, Pulmonary; Device · Drug
Lead sponsor: University of Minnesota; Other
Eligibility: Up to 36 Hours
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 7
States / cities: Loma Linda, California • San Diego, California • Maple Grove, Minnesota + 4 more

Conditions: Respiratory Insufficiency
Interventions: Nasal CPAP, Humidified High Flow Nasal Cannula (HHFNC); Other
Lead sponsor: University of Utah; Other
Eligibility: Up to 8 Weeks
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 8
States / cities: Philadelphia, Pennsylvania • Lackland Air Force Base, Texas • Ogden, Utah + 3 more

Conditions: Nose Deformities, Acquired
Interventions: 3D Scan of nares; Other
Lead sponsor: Sharp HealthCare; Other
Eligibility: 24 Weeks to 42 Weeks
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Respiratory Distress Syndrome, Cronic Lung Disease
Interventions: High Flow Nasal Cannula; Device
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 72 Hours and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Respiratory Distress Syndrome
Interventions: Lucinactant for inhalation, nCPAP alone; Combination Product · Device
Lead sponsor: Windtree Therapeutics; Industry
Eligibility: 26 Weeks to 28 Weeks
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 10
States / cities: Loma Linda, California • San Diego, California • Newark, Delaware + 7 more

Conditions: Infant, Newborn, Infant, Premature
Interventions: Low CPAP Wean, High CPAP Wean; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: Up to 32 Weeks
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obese
Interventions: nasal mask CPAP; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mild-Moderate Obstructive Sleep Disordered Breathing
Interventions: High-Flow Therapy, Continuous Positive Airway Pressure; Device
Lead sponsor: Vapotherm, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Glen Burnie, Maryland

Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: Nasal interface; Device
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: Up to 28 Days
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Little Rock, Arkansas

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Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants

Physiological Changes With High-Flow Nasal Cannula

High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation

Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants

High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Respiratory Distress Syndrome

Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)

A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact

Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP

Trial to Assess the Safety and Tolerability of Lucinactant for Inhalation in Premature Neonates

Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome

The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia

High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure

Laryngeal Mask Airway (LMA) for Surfactant Administration in Neonates

Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates

3D Imaging of Neonatal Faces

Humidified High Flow Nasal Cannula as Compared to Nasal Continuous Positive Airway Pressure

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

Determining an Optimal Weaning Method of Nasal Continuous Positive Airway Pressure in Preterm Neonates

Nasal Continuous Positive Airway Pressure and Airway Patency in Obese Patient

Non-Inferiority Trial of Acute HFT Versus nCPAP

Crossover Comparison of Tidal Volume Delivery During Nasal Intermittent Positive Pressure Ventilation in Preterm Infants: Infant Cannula vs. Nasal Continuous Positive Airway Pressure Prongs