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Conditions: Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
Interventions: Prophylactic ciNPWT, Standard Adhesive Dressing; Device · Other
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Soft Tissue Defects, Soft Tissue Wounds, Traumatic Soft Tissue Defect
Interventions: Myriad™ applied in conjunction with NPWT, NPWT Alone; Device
Lead sponsor: Aroa Biosurgery Limited; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Aurora, Colorado • San Antonio, Texas

Conditions: Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions: Usual care; Other
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 300,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2030
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Fistula, Abdominal Injury, Negative Pressure Wound Therapy
Interventions: 3D printed EAF management device; Device
Lead sponsor: Andrew Bernard; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Scarring
Interventions: Prevena, Standard of Care Dressing; Device · Procedure
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Orange, California

Conditions: Open Wound, Wound Heal
Interventions: Micro/nanobubble (MNB) - Irrigation, 0.9% Normal Saline - Irrigation, Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi), 0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi); Drug · Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Orange, California

Conditions: Foot Ulcer, Diabetic
Interventions: PriMatrix; Device
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Upper Extremity Wound, Lower Extremity Wound, Soft Tissue Abscesses, Traumatic Wounds
Interventions: Wound Vac is applied; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Wounds
Interventions: EZCare/V1STA Negative Pressure Wound Therapy System; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Diabetic Foot Ulcers
Interventions: V.A.C. Negative Pressure Wound Therapy System; Device
Lead sponsor: KCI USA, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 6
States / cities: New Haven, Connecticut • South Miami, Florida • Bethlehem, Pennsylvania + 2 more

Conditions: Negative-pressure Wound Therapy, Morbid Obesity, Cesarean Section, Wound Infection
Interventions: Negative-pressure wound therapy; Device
Lead sponsor: Albany Medical College; Other
Eligibility: 18 Years and older · Female only
Enrollment: 186 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Albany, New York

Conditions: Spine Surgery, Wounds Vac
Interventions: Wound Vac, Standard Dressing; Device · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Surgical Site Reaction
Interventions: Prevena Incision Management System, Standard of Care for Surgical Incisions; Device · Other
Lead sponsor: KCI USA, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Negative-Pressure Wound Therapy
Interventions: dry gauze, The Prevena Incision Management System; Other · Device
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 583 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2024
U.S. locations: 10
States / cities: Hartford, Connecticut • Basking Ridge, New Jersey • Middletown, New Jersey + 7 more

Conditions: High Risk Abdominal Wounds
Interventions: Negative Pressure treatment; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 95 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Open tíbia Fracture
Interventions: Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy; Drug · Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 30
States / cities: Chandler, Arizona • Tucson, Arizona • Davis, California + 25 more

Conditions: Diabetic Foot Ulcers
Interventions: Powered Suction Pump (VAC Freedom), Powered Suction Pump, MWT; Device
Lead sponsor: KCI USA, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Columbus, Ohio • San Antonio, Texas

Conditions: Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation, Wound Infection
Interventions: Prevena negative pressure wound system; Device
Lead sponsor: Abbey Hardy-Fairbanks; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Pressure Ulcers
Interventions: Quantum Negative Pressure Wound Therapy Device; Device
Lead sponsor: Innovative Therapies, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Surgical Wound Infection
Interventions: Prevena; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 80 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Wound Chronic Draining, Wound Closure
Interventions: Platelet-rich fibrin (PRF); Device
Lead sponsor: Estar Medical dba Medical Technologies, LTD; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 3
States / cities: Bradenton, Florida • San Antonio, Texas

Conditions: Pressure Ulcers Stage II, Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
Interventions: Altrazeal® Transforming Powder Dressing; Device
Lead sponsor: ULURU Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 14
States / cities: San Diego, California • Washington D.C., District of Columbia • Chicago, Illinois + 9 more

Conditions: Surgical Wound
Interventions: PICO Single Use Negative Pressure Wound Therapy System, xeroform gauze; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Frequency and Type of Medical Adhesive-Related Skin Injury, NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate), Clinician Acceptability of New NPWT Drape, Patient Drop-out Rate From Prescribed NPWT Treatment, Pain Assessment During Medical Adhesive Drape Removal
Interventions: Comfort Release® NPWT drape; Device
Lead sponsor: Global Biomedical Technologies, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 6
States / cities: Los Angeles, California • Torrance, California • Miami, Florida + 2 more

Search by objective public record fields.

NPWT Reduction Mammaplasty

Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures

A Real-World Registry of Chronic Wounds and Ulcers

Pilot Study Evaluating the Safety and Efficacy of a Patient-Specific Enteroatmospheric Fistula Isolation and Management Device Independent of Negative Pressure Wound Therapy

Prospective Observation of Wound Healing With Prevena Incision Management System

Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds

The Use of Bioscaffolds in Conjunction With Negative Pressure Therapy: A Prospective Randomized Double-Blinded Trial

VAC Bioburden Wound Care Assessment

Evaluation of the Use of EZCare/V1STA in the Management of Acute and Chronic Wounds

Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy

Prophylactic Post-Cesarean Incisional Negative-pressure Wound Therapy in Morbidly Obese Patients

Prophylactic Application of an Incisional Wound Vac to Prevent Wound Complications in Obese Spine Surgery Patients

The Use of the Prevena Incision Management System (PIMS) on Closed Incisions in Renal Transplant Subjects

Negative Pressure Wound Therapy in Post-Operative Incision Management

Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

A Trial Examining Cellular Energetics Related to Various Wound Treatment Therapies

Negative Pressure Wound Therapy After Cesarean Delivery

Efficacy of Quantum NPWT With Simultaneous Irrigation on Reduction of Wound Volume in Stage III/IV Pressure Ulcers.

Prophylactic NPWT to Reduce SSI in Colorectal Surgery

Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds

Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries

Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites

Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.