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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Nerve decompression Clear all
Not listed No phase listed Observational

Objective Measures of Nerve Integrity, Posture, Gait and Blood Flow, After Nerve Decompression

NCT01735903
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Arm A - Non-Diabetic, Gait and Balance
Procedure
Lead sponsor
Foot Surgery Center of Northern Colorado
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 5, 2026, 2:38 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Actions of Osteopathic Manipulative Treatment

NCT04177264
View directory record Official record
Conditions
Inflammation
Interventions
Occipito-Atlantal Decompression (OA DC), Sham Occipito-Atlantal Decompression (Sham OA DC), Splenic Lymphatic Pump Technique (SpLPT), Sham Splenic Lymphatic Pump Technique (Sham SpLPT), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS)
Procedure · Device
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Phase 4 Interventional Results available

(Botox) Mechanisms of Action in Altering the Molecular Environment in Which Pain Fibers Exist

NCT03381261
View directory record Official record
Conditions
Migraine
Interventions
Botulinum toxin type A
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 5, 2026, 2:38 PM EDT
Recruiting Not applicable Interventional

Can Prophylactic Foraminotomy Prevent C5 Palsy

NCT03023696
View directory record Official record
Conditions
Myelopathy, Compressive, Radiculopathy, Cervical, C5 Palsy
Interventions
Bilateral Cervical Keyhole Foraminotomy, Cervical Decompression
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 5, 2026, 2:38 PM EDT
Terminated Not applicable Interventional

The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine

NCT01495624
View directory record Official record
Conditions
Duration of Interscalene Block
Interventions
ropivacaine plus dexamethasone anesthetic, ropivacaine plus saline plus dexamethasone anesthetic
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Sep 5, 2026, 2:38 PM EDT
Active, not recruiting Not applicable Interventional Results available

The MOTION Study - Treatment of LSS With the MILD Procedure

NCT03610737
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions
MILD Procedure, Conventional Medical Management (CMM)
Device · Other
Lead sponsor
Vertos Medical, Inc.
Industry
Eligibility
50 Years to 80 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
18
States / cities
Newport Beach, California • Colorado Springs, Colorado • Lakeland, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 5, 2026, 2:38 PM EDT
Withdrawn Not applicable Interventional

Post-traumatic Occipital Neuralgia - Surgical Versus Medical Management

NCT03253523
View directory record Official record
Conditions
Post-Traumatic Neuralgia, Occipital Neuralgia
Interventions
Occipital neurolysis
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 5, 2026, 2:38 PM EDT
Recruiting Not applicable Interventional

Spinal Decompression Plus Nerve Graft Implantation Following TSCI

NCT06243211
View directory record Official record
Conditions
Spinal Cord Injuries, Acute Traumatic Spinal Cord Injury
Interventions
DMED, ANGI
Procedure
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 5, 2026, 2:38 PM EDT
Active, not recruiting Not applicable Interventional

The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery

NCT05740176
View directory record Official record
Conditions
Cervical Degenerative Disc Disease
Interventions
Anterior Cervical Discectomy and Fusion
Device
Lead sponsor
Synergy Spine Solutions
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
23
States / cities
Scottsdale, Arizona • Beverly Hills, California • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 5, 2026, 2:38 PM EDT
Not listed Not applicable Interventional

Nerve Decompression for Ulcer Recurrence Avoidance (DURA)

NCT01762085
View directory record Official record
Conditions
Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot, Diabetic Polyneuropathy
Interventions
nerve decompression
Procedure
Lead sponsor
Association of Extremity Nerve Surgeons
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2015 · Synced Sep 5, 2026, 2:38 PM EDT
Active, not recruiting Not applicable Interventional

Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

NCT04254185
View directory record Official record
Conditions
Neuropathy Ulnar
Interventions
Simple decompression, Subcutaneous anterior transposition
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
378 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
10
States / cities
Atlanta, Georgia • Louisville, Kentucky • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Not applicable Interventional

Comparing the Outcomes Between Rotator Cuff Repair With and Without Suprascapular Nerve Decompression

NCT02107573
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Rotator Cuff Repair without Suprascapular Nerve decompression, Rotator Cuff Repair with Suprascapular Nerve decompression
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Sep 5, 2026, 2:38 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

MRI Outcomes of VersaWrap Nerve Protector Following Surgery

NCT06942819
View directory record Official record
Conditions
Lumbar Decompression
Interventions
VersaWrap Nerve Protector
Device
Lead sponsor
Research Source
Network
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 5, 2026, 2:38 PM EDT
Recruiting No phase listed Observational

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

NCT06859801
View directory record Official record
Conditions
Bone Cancer Metastatic
Interventions
Percutaneous Ablation, Radiation Therapy
Device · Radiation
Lead sponsor
Society of Interventional Oncology
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
San Diego, California • Miami, Florida • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 5, 2026, 2:38 PM EDT
Withdrawn Not applicable Interventional

Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

NCT03543033
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Corticosteroid injection
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
30 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Not applicable Interventional

Coflex PS3 Actual Conditions for Use Study

NCT02555280
View directory record Official record
Conditions
Spinal Stenosis Lumbar
Interventions
coflex® Interlaminar Technology, Decompression
Device · Procedure
Lead sponsor
Companion Spine, LLC
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
14
States / cities
Phoenix, Arizona • Sacramento, California • San Luis Obispo, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Phase 4 Interventional

Prospective, Randomized, Multi-center Clinical Study of Plasma Disc Decompression

NCT00189605
View directory record Official record
Conditions
Radicular Pain
Interventions
Perc-DLR/Perc-DLG, Fluoroscopy guided transforaminal epidural steroid injection (TFESI)
Device · Drug
Lead sponsor
ArthroCare Corporation
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
13
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Napa, California + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Phase 3 Interventional

Greenwich Lumbar Stenosis SLIP Study

NCT00109213
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis
Interventions
Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy
Procedure
Lead sponsor
Greenwich Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
5
States / cities
Greenwich, Connecticut • Boston, Massachusetts • Burlington, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation

NCT00000410
View directory record Official record
Conditions
Herniated Disc, Low Back Pain
Interventions
Diskectomy, Non-surgical treatments
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 5, 2026, 2:38 PM EDT
Completed Phase 4 Interventional Results available

Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis

NCT00995371
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection
Device · Drug
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced Sep 5, 2026, 2:38 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Electrical Nerve Stimulation of the Ulnar Nerve

NCT02566616
View directory record Official record
Conditions
Cubital Tunnel Syndrome
Interventions
Ulnar Nerve Stimulation
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 5, 2026, 2:38 PM EDT
Completed No phase listed Observational

Outpatient Posterior Cervical Fusion: Outcomes of the First 100 Consecutive Cases

NCT07242989
View directory record Official record
Conditions
Cervical Stenosis
Interventions
Enhanced recovery after surgery protocol
Other
Lead sponsor
NeuroSpine Center of Wisconsin
Other
Eligibility
Not listed
Enrollment
100 participants
Timeline
2019 – 2025
U.S. locations
1
States / cities
Neenah, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 5, 2026, 2:38 PM EDT
Withdrawn Not applicable Interventional

Acute Nerve Decompression Versus Non-operative Treatment for Peroneal Nerve Palsy Following Primary Total Knee Arthroplasty

NCT02856958
View directory record Official record
Conditions
Peroneal Palsy (Foot Drop)
Interventions
Nerve decompression, Non-operative
Procedure · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 5, 2026, 2:38 PM EDT
Active, not recruiting Not applicable Interventional

Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression

NCT06117501
View directory record Official record
Conditions
Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Interventions
Axoguard HA+ Nerve Protector™
Device
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Tampa, Florida • Savannah, Georgia • Indianapolis, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 5, 2026, 2:38 PM EDT