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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:57 AM EDT

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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Nexplanon Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial

NCT02866279
View directory record Official record
Conditions
Contraception, Breastfeeding, Postpartum Contraception
Interventions
Etonogestrel Contraceptive Implant
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
17 Years to 45 Years · Female only
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Immediate vs. Delayed Postpartum Etonogestrel Implant

NCT01767285
View directory record Official record
Conditions
Continuation Rate of Contraceptive Implant
Interventions
Etonogestrel implant
Drug
Lead sponsor
Duke University
Other
Eligibility
12 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Early Phase 1 Interventional Results available

Ovarian Function With ENG Implant and UPA Use

NCT04291001
View directory record Official record
Conditions
Contraception
Interventions
ENG implant, oral ulipristal acetate
Device · Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Hormonal Contraception on HIV Acquisition and Transmission Risk

NCT02357368
View directory record Official record
Conditions
HIV, Contraception
Interventions
Depot medroxyprogesterone acetate (DMPA), Etonogestrel implant (Eng-Implant), Levonorgestrel intrauterine device (Lng-IUD), ParaGard® T 380A Intrauterine Copper Contraceptive
Drug · Device
Lead sponsor
Lisa Haddad
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
4
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 21, 2026, 4:57 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Antepartum Etonogestrel Contraceptive Implant Insertion at Term

NCT03656289
View directory record Official record
Conditions
Contraception
Interventions
Etonogestrel 68Mg Implant
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 34 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 21, 2026, 4:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long-Acting Progestin Contraception and the Vaginal Microbiome

NCT02740998
View directory record Official record
Conditions
Sexually Transmitted Infection
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Contraception on Postpartum Weight Loss

NCT02144259
View directory record Official record
Conditions
Weight
Interventions
DMPA immediately postpartum, Implanon immediately postpartum
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Postpartum Etonogestrel Implant for Adolescents

NCT01666912
View directory record Official record
Conditions
Adolescence, Contraception, Postpartum
Interventions
Contraceptive implant
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 24 Years · Female only
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Breastfeeding Etonogestrel Implant Study

NCT03978598
View directory record Official record
Conditions
Contraception
Interventions
Etonogestrel, Nexplanon
Drug · Device
Lead sponsor
University of New Mexico
Other
Eligibility
13 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Albuquerque, New Mexico • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 21, 2026, 4:57 AM EDT
Completed No phase listed Observational

Duration of Use of Highly Effective Reversible Contraception

NCT02414919
View directory record Official record
Conditions
Pregnancy
Interventions
Mirena (Levonorgestrel IUS, BAY86-5028), ParaGard, Implanon/Nexplanon
Drug
Lead sponsor
Bayer
Industry
Eligibility
15 Years to 44 Years · Female only
Enrollment
13,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Labor and Delivery Implant Insertion: A Randomized Controlled Trial

NCT02866643
View directory record Official record
Conditions
Postpartum Contraception, Family Planning
Interventions
Etonogestrel-Immediate, Etonogestrel-Delayed
Drug
Lead sponsor
Stanford University
Other
Eligibility
Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Not applicable Interventional Results available

Nexplanon Application Post-Abortion (NAPA)

NCT02037919
View directory record Official record
Conditions
Contraception, Abortion, Therapeutic
Interventions
Immediate Nexplanon Insertion, Post-op Nexplanon Insertion
Other
Lead sponsor
Family Planning Associates Medical Group, LTD
Other
Eligibility
18 Years and older · Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Oct 21, 2026, 4:57 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

LARC Forward Contraceptive Counseling at MHCC

NCT02735551
View directory record Official record
Conditions
Contraception
Interventions
Long Acting Reversible Contraception (LARC), Referral for Long Acting Reversible Contraception (LARC), Prescription for Short-Acting Hormonal Contraception
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
17 Years to 30 Years · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Gresham, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 21, 2026, 4:57 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Keep Contraceptive Arm Long Acting-iMplant (CALM) and Carry On

NCT04725643
View directory record Official record
Conditions
Contraception, Contraceptive Usage, Family Planning
Interventions
Track bleeding patterns before and after implant
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 21, 2026, 4:57 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Effects of a Progestin on Frequent and/or Prolonged Bleeding With Nexplanon™

NCT04676061
View directory record Official record
Conditions
Birth Control, Contraception, Implant, Breakthrough Bleeding, Uterine Bleeding
Interventions
Norethindrone acetate (NTA), Placebo
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
14 Years to 48 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 21, 2026, 4:57 AM EDT
Active, not recruiting Phase 4 Interventional

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

NCT05730205
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Nexplanon 68 MG Drug Implant
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 21, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vapocoolant Spray to Reduce Pain With Nexplanon Insertion

NCT06933381
View directory record Official record
Conditions
Reducing Pain With Nexplanon Implant Insertion
Interventions
Vapocoolant spray, Placebo
Device · Other
Lead sponsor
Queen's Medical Center
Other
Eligibility
14 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Honolulu, Hawaii • Waimea, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 4:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Quantification of Immune Cells in Women Using Contraception (CHIC II)

NCT01873170
View directory record Official record
Conditions
HIV, Immune Cells (Mucosal and Systemic), Contraception
Interventions
levonorgestrel exposure, DMPA exposure, etonogestrel exposure, IUD insertion, subdermal contraceptive implant insertion
Drug · Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 34 Years · Female only
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Nexplanon Use in Women Primarily Choosing a Combined Oral Contraceptive

NCT04423055
View directory record Official record
Conditions
Contraception
Interventions
Etonogestrel contraceptive implant
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
3
States / cities
Sacramento, California • Denver, Colorado • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 21, 2026, 4:57 AM EDT
Recruiting No phase listed Observational

Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant.

NCT06357442
View directory record Official record
Conditions
Primary Ovarian Insufficiency, Hypogonadotropic Hypogonadism, Hormone Replacement Therapy
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 25 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 21, 2026, 4:57 AM EDT
Completed No phase listed Observational

Quick Start of Highly Effective Contraception

NCT02076217
View directory record Official record
Conditions
IUD, Contraceptive Implant, Contraception, Birth Control, Emergency Contraception
Interventions
Copper T-380 IUD, LNG IUD, Contraceptive implant Nexplanon, Depo-Provera
Drug · Device
Lead sponsor
University of Utah
Other
Eligibility
15 Years to 45 Years · Female only
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Immediate Versus Delayed Insertion of Implanon in Postpartum Adolescents

NCT03585504
View directory record Official record
Conditions
Contraceptive Usage
Interventions
Etonogestrel contraceptive implant
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
15 Years to 21 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Results available

Management of Etonogestrel Subdermal Implant-related Bleeding

NCT01658995
View directory record Official record
Conditions
ESI-related Bleeding
Interventions
Doxycycline, Placebo
Drug
Lead sponsor
Petra M. Casey
Other
Eligibility
18 Years to 51 Years · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Oct 21, 2026, 4:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Nexplanon and Combined Oral Contraceptive (COC) Combined Use Study

NCT02852265
View directory record Official record
Conditions
Contraception
Interventions
Etonogestrel contraceptive implant
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
16 Years to 35 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2018 · Synced Oct 21, 2026, 4:57 AM EDT