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ClinicalTrials.gov public records Last synced Oct 22, 2026, 9:57 AM EDT

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Showing 217–240 of 286 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Next Science Clear all
Terminated Phase 3 Interventional Results available

Efficacy and Safety of Tranexamic Acid in Spinal Fusion Surgery

NCT03425799
View directory record Official record
Conditions
Spinal Fusion
Interventions
Sodium Chloride 0.9% Inj, Tranexamic Acid
Drug
Lead sponsor
Exela Pharma Sciences, LLC.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Long Beach, California • Los Angeles, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Oct 22, 2026, 9:57 AM EDT
Not yet recruiting Not applicable Interventional

Scaling Out S.A.F.E. Firearm Across Two Health Systems as a Universal Suicide Prevention Strategy (SCALE ASPIRE)

NCT07009314
View directory record Official record
Conditions
Suicide
Interventions
Implementation package (training, facilitation, electronic health record nudge)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
5,442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional

Comparative Effectiveness Trial of Two Reminder/Recall Methods to Increase Immunization Rates in Young Children

NCT01557621
View directory record Official record
Conditions
Immunization Rates
Interventions
Collaborative Pop-Based R/R: Phone/Mail Group, Collaborative Pop-Based R/R: Mail-Only Group, Practice-based Recall
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
19 Months to 5 Years
Enrollment
68,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Next Science Antimicrobial Mouth Rinse Study

NCT03154021
View directory record Official record
Conditions
Gingivitis, Dental Plaque
Interventions
Next Science OTC Oral Rinse with Essential Oils, OTC Oral Rinse Control
Combination Product
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Phase 4 Interventional Results available

Desensitization in Kidney Transplantation

NCT00908583
View directory record Official record
Conditions
HLA Sensitization
Interventions
plasmapheresis, Bortezomib, Rituximab, Methylprednisolone
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2016 · Synced Oct 22, 2026, 9:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle

NCT02872831
View directory record Official record
Conditions
Pancreatic Cancer, Lymphadenopathy, Cholangiocarcinoma
Interventions
22G SharkCore™ needle, 22G BNX EUS-FNA Needle
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Recruiting Phase 1 Interventional

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

NCT06065371
View directory record Official record
Conditions
Gastrointestinal Cancer
Interventions
Capecitabine, Sacituzumab govetican
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional

A Megastudy of Single-Session Interventions for Depression

NCT06856668
View directory record Official record
Conditions
Depression - Major Depressive Disorder
Interventions
Behavioral Activation (Action Brings Change Project 10-Minute Version), Mindful Acceptance, Moral Elevation, Mindful Attention Skills, 5 Habits to Beat Depression, Interactive Cognitive Reappraisal, Expressive Writing (AI-supported), Inner Child Healing Walk, Savoring Strategies, Personalized Intervention Recommender, Dialectical Behavioral Therapy Skills, All about Trout, Reframing Negative Thoughts
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
7,505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Centervention-ATOD: An Implementation Tool for Dissemination of Evidence-based Programs for Substance Abuse

NCT03084406
View directory record Official record
Conditions
Substance Abuse
Interventions
Centervention-ATOD (CV-ATOD)
Other
Lead sponsor
3-C Institute for Social Development
Industry
Eligibility
11 Years to 65 Years
Enrollment
327 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional

Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode

NCT02823041
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
Interventions
Cognitive Training, Aerobic Exercise, Case management and supportive psychotherapy, Individual Placement and Support
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting

NCT07711301
View directory record Official record
Conditions
Health Knowledge, Attitudes, Practices
Interventions
Science Tooth Fairy Narrative, Cavities vs. Toothpaste, book by Didi Dragon
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of a Two-tiered Cross-age Teaching Model for Food Literacy-based Education

NCT04098419
View directory record Official record
Conditions
Food Literacy; Adolescent Health; Cross-age Teaching; Nutrition Education; Experiential Learning
Interventions
Science for Life
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
9 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 22, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional

Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy

NCT07220590
View directory record Official record
Conditions
Cerebral Palsy Children, Motor Disabilities, Developmental Disability, Rehabilitation, Early Intervention, Assistive Technology
Interventions
Therapist Training on Powered Mobility Implementation, Powered Mobility Intervention for Child-Caregiver Dyads
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
12 Months and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
Hillsboro, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Results available

Translating Data Science to Palliative Care

NCT05942040
View directory record Official record
Conditions
Alzheimer's Disease and Related Dementias
Interventions
Tailored Palliative Care Information
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 22, 2026, 9:57 AM EDT
Not listed Not applicable Interventional

Promoting Treatment Access Following Pediatric Primary Care Depression Screening

NCT04030897
View directory record Official record
Conditions
Depression
Interventions
Parent-Directed Online Single-Session Program, Youth-Directed Online Single-Session Program, Information/Psychoeducation/Referral
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
11 Years to 16 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2020 · Synced Oct 22, 2026, 9:57 AM EDT
Withdrawn Not applicable Interventional

Online Spanish Cognitive Intervention Program for Spanish-Speaking Latino/Hispanic Subarachnoid Hemorrhage Patients

NCT03621397
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cognitive Impairment, Quality of Life, Depression, Anxiety
Interventions
brainHQ by Posit Science
Device
Lead sponsor
DHR Health Institute for Research and Development
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Edinburg, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 22, 2026, 9:57 AM EDT
Not listed Not applicable Interventional

ESWL vs. Pancreatoscopy-guided Lithotripsy for Painful Chronic Calcific Pancreatitis

NCT04115826
View directory record Official record
Conditions
Pancreatitis, Chronic
Interventions
Per-oral Pancreatoscopy-guided Lithotripsy, Extracorporeal Shock-Wave Lithotripsy
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 22, 2026, 9:57 AM EDT
Not listed Not applicable Interventional

Warfarin Patient Self-management Implementation in the US Healthcare System

NCT04766216
View directory record Official record
Conditions
Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases
Interventions
Patient self-management, Usual care provided by anticoagulation providers
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Loma Linda, California • Boston, Massachusetts • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 22, 2026, 9:57 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

ANCHORS Alcohol & Sexual Health Study: UH3 Project

NCT04331704
View directory record Official record
Conditions
Alcohol Use, Unspecified, Substance Use, Sex Behavior
Interventions
PrEP acronym (pre-exposure prophylaxis), Initial Web Survey, Interactive Voice Response (IVR) monitoring, Educational material on alcohol and sexual health behavior, Interactive Voice Response (IVR) assessment with personalized information, Personalized information based on web-based survey responses & standardized information
Drug · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 22, 2026, 9:57 AM EDT
Active, not recruiting Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK

NCT06556368
View directory record Official record
Conditions
Wet Age-related Macular Degeneration
Interventions
Tarcocimab tedromer, Tabirafusp tedromer, Aflibercept
Drug
Lead sponsor
Kodiak Sciences Inc
Industry
Eligibility
50 Years and older
Enrollment
675 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
71
States / cities
Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 66 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional

Investigation of the Freespira Breathing System in the Treatment of Post Traumatic Stress Disorder (PTSD)

NCT03039231
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Freespira Breathing System
Device
Lead sponsor
Palo Alto Health Sciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 22, 2026, 9:57 AM EDT
Not yet recruiting Not applicable Interventional

Access to Care Pilot for ED-Presenting Head and Neck Cancer Patients (ENRICH-HNC)

NCT07225725
View directory record Official record
Conditions
Head and Neck Neoplasms, Emergency Department Presentation, Head and Neck Cancer (H&N)
Interventions
Community Health Support Specialist (CHSS) Navigation
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Orlando, Florida • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Media Influences on Perceptions of Alternative Nicotine and Nicotine-like Vaping Products Among Youth and Young Adults (AYA)

NCT07849790
View directory record Official record
Conditions
Vaping
Interventions
An image resembling a social media post
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 25 Years
Enrollment
2,829 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 9:57 AM EDT
Completed No phase listed Observational

Biomarkers in Samples From Younger Patients With Wilms Tumor

NCT01493817
View directory record Official record
Conditions
Wilms Tumor and Other Childhood Kidney Tumors
Interventions
laboratory biomarker analysis
Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Monrovia, California
Source: ClinicalTrials.gov public record
Updated May 19, 2016 · Synced Oct 22, 2026, 9:57 AM EDT