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ClinicalTrials.gov public records Last synced Sep 17, 2026, 2:55 AM EDT

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Showing 1–5 of 5 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2Phase 3 Interventional Results available

PRecision Interventions for SMoking in the SCCS

NCT03521141
Conditions
Tobacco Use Cessation
Interventions
Nicotine patch, Varenicline, Nicotine metabolism, Genetically-informed lung cancer risk score, NCI "Clearing the Air"
Drug · Genetic · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Smoking Cessation
Interventions
Nicotine Metabolite Ratio
Other
Lead sponsor
Southcentral Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Anchorage, Alaska
Completed Not applicable Interventional Accepts healthy volunteers Results available

Precision Pharmacotherapy Smoking Cessation Program

NCT04897607
Conditions
Smoking Cessation
Interventions
Standard Care, Precision pharmacotherapy
Behavioral
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Newark, Delaware
Completed Phase 3 Interventional Results available

Metabolism Informed Smoking Treatment: The MIST RCT

NCT04590404
Conditions
Smoking
Interventions
Post-discharge automated phone calls (IVR) with option to connect with a tobacco coach., Nicotine Replacement Therapy, Varenicline, Metabolism Informed Smoking Treatment (Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy)
Behavioral · Drug · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
606 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Completed No phase listed Observational Accepts healthy volunteers Results available

Metabolism of NNK in Japanese Americans

NCT04228952
Conditions
Smoking
Interventions
Modified Natural American Spirit-Tan or Green cigarettes injected with labeled NNK
Combination Product
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Honolulu, Hawaii