- Conditions
- Argininosuccinic Aciduria, Argininosuccinate Lyase Deficiency, Urea Cycle Disorders
- Interventions
- Nitric oxide supplement, Placebo
- Dietary Supplement
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 8 Years to 64 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Houston, Texas
Search Results
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Showing 1–24
of 34
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Pulmonary Arterial Hypertension, Idiopathic Pulmonary Fibrosis
- Interventions
- Inhaled Nitric Oxide
- Drug
- Lead sponsor
- Geno LLC
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • Los Angeles, California • Sacramento, California + 7 more
- Conditions
- Aging, Endothelial Dysfunction, Senescence
- Interventions
- Supplement with ginger extract, L-citrulline, Paullinia cupana, and muira puama
- Dietary Supplement
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Santa Monica, California
- Conditions
- COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
- Interventions
- Tetrahydrobiopterin, Placebo oral tablet
- Drug
- Lead sponsor
- University of Massachusetts, Amherst
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Amherst, Massachusetts
- Conditions
- Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
- Interventions
- iNO, Nitrogen
- Drug · Other
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 1 Minute to 2 Minutes
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 2
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Endothelial Dysfunction
- Interventions
- Dietary nitrate in the form of beetroot juice for all participnats, Nature Made vitamin c 1000 mg, Placebo
- Dietary Supplement
- Lead sponsor
- David Travis Thomas
- Other
- Eligibility
- 50 Years to 70 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky
- Conditions
- Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
- Interventions
- Cocoa Flavanol Supplement, Low-Flavanol Control Powder
- Dietary Supplement
- Lead sponsor
- The Black Forest LLC
- Industry
- Eligibility
- 30 Years to 75 Years · Male only
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- Miami, Florida
- Conditions
- Excessive Physical Exercise, Unspecified
- Interventions
- Arginine antioxidant supplements, Placebo
- Dietary Supplement
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2005
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- COVID-19, Hypoxemia, Hypoxemic Respiratory Failure
- Interventions
- Inhaled nitric oxide (iNO), Nitrogen gas, Oxygen gas
- Drug
- Lead sponsor
- Roger Alvarez
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Preeclampsia, Preeclampsia Postpartum
- Interventions
- Eplerenone
- Drug
- Lead sponsor
- Anna Stanhewicz, PhD
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Ketosis Prone Diabetes
- Interventions
- Citrulline, Alanine
- Dietary Supplement
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 20 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Healthy
- Interventions
- Beetroot Juice, Placebo Control
- Dietary Supplement
- Lead sponsor
- Baylor University
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 2
- States / cities
- Dallas, Texas • Waco, Texas
- Conditions
- Osteoporosis, Osteopenia
- Interventions
- Nitroglycerin ointment, Calcium supplement with vitamin D
- Drug
- Lead sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- NIH
- Eligibility
- 40 Years to 65 Years · Female only
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2007
- U.S. locations
- 1
- States / cities
- New Brunswick, New Jersey
- Conditions
- Blood Pressure, Racial Disparities, Cardiovascular Risk Factor
- Interventions
- Acute Beetroot Juice
- Other
- Lead sponsor
- Georgia Southern University
- Other
- Eligibility
- 18 Years to 39 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Savannah, Georgia
- Conditions
- Healthy
- Interventions
- MitoQ, Placebo, MitoTempo, Tempol, L-NAME, SNP - Sodium Nitroprusside
- Dietary Supplement · Drug
- Lead sponsor
- University of Georgia
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2030
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Healthy
- Interventions
- Placebo, Nitrate supplement with caffeine
- Dietary Supplement
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 21 Years to 49 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Idiopathic Pulmonary Arterial Hypertension, Cardiomyopathy
- Interventions
- Nitric Oxide for inhalation, Oxygen, Nitric Oxide plus Oxygen
- Drug
- Lead sponsor
- Mallinckrodt
- Industry
- Eligibility
- 4 Weeks to 18 Years
- Enrollment
- 136 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2010
- U.S. locations
- 8
- States / cities
- Stanford, California • Denver, Colorado • Boston, Massachusetts + 5 more
- Conditions
- Heart Failure With Normal Ejection Fraction
- Interventions
- Active lozenge, Placebo
- Dietary Supplement · Drug
- Lead sponsor
- MaineHealth
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Rockport, Maine
- Conditions
- Congenital Heart Disease, Acute Kidney Injury
- Interventions
- NO gas delivered during cardiac surgery, placebo gas delivered during cardiac surgery
- Drug · Other
- Lead sponsor
- Fabio Savorgnan
- Other
- Eligibility
- Up to 30 Days
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Burns
- Interventions
- Alteration in nutritional support
- Dietary Supplement
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 2009
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction
- Interventions
- BQ-788, BQ-123, L-Arginine, NG Nitro L Arginine Methyl Ester, Sodium Nitroprusside, Lactated Ringer's
- Drug
- Lead sponsor
- The University of Texas at Arlington
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Arlington, Texas
- Conditions
- Hypertension
- Interventions
- Inorganic Nitrate
- Dietary Supplement
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Healthy
- Interventions
- concentrated beet root juice, Placebo beet root juice
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 34 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- COVID19
- Interventions
- Nitric Oxide Gas, Inhaled Supplemental Oxygen
- Drug · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts