Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 4, 2026, 9:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 48 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Non-Invasive Infrared Spectroscopy Clear all
Completed No phase listed Observational

RBC Irradiation, Anemia and Gut Injury

NCT02741648
View directory record Official record
Conditions
Anemia, Necrotizing Enterocolitis
Interventions
Near Infrared Spectroscopy, Non-invasive Image-based Anemia Assessment
Device · Other
Lead sponsor
Emory University
Other
Eligibility
1 Day to 5 Days
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

NCT07044596
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post Concussion Syndrome
Interventions
Functional near-infrared spectroscopy (fNIRS), V1 stimulation electrodes, Magnetic Resonance Imaging (MRI), MAGNUS scanner
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Active, not recruiting Not applicable Interventional

TMS-fNIRS Personalized Dosing

NCT05916417
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
TMS-fNIRS over the dl-PFC
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Completed Not applicable Interventional Results available

Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion

NCT01812109
View directory record Official record
Conditions
Acute Scrotum, Testicular Torsion
Interventions
Hutchison Technologies Inspectra StO2 SpotCheck Near-Infrared Spectroscopy
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
1 Month to 21 Years · Male only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational

Autoregulation Assessment During Liver Transplantation

NCT01425385
View directory record Official record
Conditions
Liver Failure, Liver Transplantation, Encephalopathy
Interventions
Near infrared spectroscopy monitoring, Autoregulation monitoring
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Sep 4, 2026, 9:47 AM EDT
Completed Not applicable Interventional

Assessing the Feasibility of a Novel Non-Invasive Sensor for Guiding Wounded Warrior Rehabilitation

NCT02887755
View directory record Official record
Conditions
Rehabilitation Post-amputation
Interventions
Near-Infrared Spectroscopy (NIRS) Sensor
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational

Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)

NCT05604547
View directory record Official record
Conditions
SCD
Interventions
Non-Invasive Infrared Spectroscopy
Diagnostic Test
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 4, 2026, 9:47 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements

NCT07294924
View directory record Official record
Conditions
Major Depressive Disorder (MDD), fNIRS
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Los Angeles, California • Sunnyvale, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Sport-Related Concussion Recovery in Athletes

NCT06852300
View directory record Official record
Conditions
Concussion Mild, Concussion, Brain
Interventions
Concussion Assessment Battery
Device
Lead sponsor
University of Central Arkansas
Other
Eligibility
18 Years to 26 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Conway, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Sep 4, 2026, 9:47 AM EDT
Not listed No phase listed Observational

BWH Critical Care Study of CareGuide for Evaluation of Emerging or Established Shock

NCT03060369
View directory record Official record
Conditions
Shock
Interventions
CareGuide™ device
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 4, 2026, 9:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Validation Study of Bioelectronics

NCT05397951
View directory record Official record
Conditions
Healthy, Health Behavior
Interventions
Multi-modality Noninvasive Biosensor, Oximeter, Portable Blood Pressure Monitor, Vicorder Pulse Wave Velocity Monitor
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Withdrawn Not applicable Interventional

Non-invasive Near-infrared Spectroscopy (NIRS) Versus Invasive Licox Intracranial Pressure

NCT04247321
View directory record Official record
Conditions
Brain Injuries
Interventions
Licox® Brain Tissue Oxygen Monitoring System, Near-infrared spectroscopy (NIRS)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Sep 4, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults

NCT06995560
View directory record Official record
Conditions
Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition, Psychomotor Performance, Neurophysiology
Interventions
Active Transcranial Electrical Stimulation, Sham Transcranial Electrical Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Not listed No phase listed Observational

The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome

NCT01171638
View directory record Official record
Conditions
Acute Compartment Syndrome
Interventions
Near infrared spectroscopy (NIRS)
Device
Lead sponsor
J&M Shuler
Industry
Eligibility
15 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2011 · Synced Sep 4, 2026, 9:47 AM EDT
Enrolling by invitation No phase listed Observational

Changes in Cerebral Oxygenation Related to Intraoperative Position Changes

NCT06910228
View directory record Official record
Conditions
Scoliosis Patients
Interventions
Near infrared spectroscopy (NIRS)
Device
Lead sponsor
Joseph D. Tobias
Other
Eligibility
10 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational

Functional Near Infrared Spectroscopy to Detect Pain in Young Children Under General Anesthesia

NCT04362423
View directory record Official record
Conditions
Pain
Interventions
fNIRS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 16 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Sep 4, 2026, 9:47 AM EDT
Terminated Not applicable Interventional Results available

Validation of Brain Oxygenation Monitor on Pediatric Patients

NCT00849940
View directory record Official record
Conditions
Cardiac Catheterization
Interventions
CAS NIRS FORE-SIGHT oximeter
Device
Lead sponsor
Duke University
Other
Eligibility
Up to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Sep 4, 2026, 9:47 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Non-invasive Characterization of Systemic Microvascular Reactivity by Near-infrared Diffuse Optical Spectroscopy in COVID-19 Patients

NCT04689477
View directory record Official record
Conditions
COVID-19, Endothelial Function
Interventions
Vascular occlusion test
Device
Lead sponsor
Corporacion Parc Tauli
Other
Eligibility
18 Years and older
Enrollment
612 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 4, 2026, 9:47 AM EDT
Recruiting Not applicable Interventional

Using Light Therapy for Mild Cognitive Impairment

NCT07651787
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Amyloid Pathology
Interventions
Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation, Sham Vielight Neuro RX-Duo device -Sham transcranial photobiomodulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
55 Years to 95 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational

Study of Non-Invasive Regional Oxygen Saturations in Pediatric Patients Undergoing Cardiac Catheterization

NCT00939224
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Model 7600 Regional Oximeter System
Device
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
Up to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Stanford, California • Chicago, Illinois • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2011 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational

Correlation of Physical Exam Versus Non-invasive Assessment Versus Invasive Assessment of Central Venous Pressure

NCT01574690
View directory record Official record
Conditions
Central Venous Pressure
Interventions
Mespere Venus System, Right heart catheterization (RHC), Physical examination of jugular vein
Device · Procedure
Lead sponsor
Mespere Lifesciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 7, 2013 · Synced Sep 4, 2026, 9:47 AM EDT
Completed Not applicable Interventional Results available

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

NCT02926677
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational Results available

Total Shoulder Arthroplasty Near-infrared Spectroscopy

NCT02198183
View directory record Official record
Conditions
Cerebral Ischemia
Interventions
Casmed Fore-Sight Elite, Non-invasive Cardiac Output Monitor (NICOM)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2023 · Synced Sep 4, 2026, 9:47 AM EDT
Completed No phase listed Observational

Assessment of Near Infrared Spectroscopy as a Diagnostic Tool in Acute Compartment Syndrome

NCT01077934
View directory record Official record
Conditions
Compartment Syndrome
Interventions
near-infrared spectroscopy
Device
Lead sponsor
J&M Shuler
Industry
Eligibility
13 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Sep 4, 2026, 9:47 AM EDT