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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:03 AM EDT

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Showing 169–192 of 230 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Non-Invasive Ventilation Clear all
Terminated No phase listed Interventional Results available

Determination of the Prevalence and Severity of Expiratory Flow Limitation in Chronic Obstructive Pulmonary Disease Patients

NCT03851510
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Noninvasive Ventilation
Interventions
Vector ventilator, Resmon Pro
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
40 Years to 80 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Work of Breathing During Non-invasive Ventilation in Premature Neonates

NCT02788110
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn, Bronchopulmonary Dysplasia
Interventions
Noninvasive neurally adjusted ventilatory assist (NIV NAVA), Nasal intermittent positive pressure ventilation (NIPPV)
Other
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
Up to 12 Months
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2019 · Synced Oct 22, 2026, 1:03 AM EDT
Completed No phase listed Observational

Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35

NCT01825278
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea
Interventions
ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Liberation From Acute Dialysis

NCT04218370
View directory record Official record
Conditions
Acute Kidney Injury, Kidney; Disease, Acute, Dialysis Related Complication
Interventions
Dialysis
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
4
States / cities
San Francisco, California • St Louis, Missouri • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress

NCT04935697
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Acute Lung Injury, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Traumatic Brain Injury
Interventions
nVNS, SOC
Device · Other
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
12 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 22, 2026, 1:03 AM EDT
Completed No phase listed Observational

Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma

NCT04205708
View directory record Official record
Conditions
Silicosis, Pneumoconiosis; Silica
Interventions
Tuberculosis test, Chest X-ray, Pulmonary Function Test
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
30 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 22, 2026, 1:03 AM EDT
Completed No phase listed Observational

Respiratory Supports and COVID-19 Mortality

NCT04832061
View directory record Official record
Conditions
COVID-19
Interventions
Respiratory supports
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 22, 2026, 1:03 AM EDT
Terminated Not applicable Interventional

Exercise Intolerance and Skeletal Muscle Bioenergetics in Children With Deep Venous Thrombosis

NCT04294849
View directory record Official record
Conditions
Deep Vein Thrombosis, Pulmonary Embolism
Interventions
Magnetic Resonance Imaging, Bicycle Ergometry, Lab Panel, Questionnaires
Other · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

EIT Assessment of Lung Volume and Tidal Distribution: A Comparison of Non-Invasive Ventilation Devices

NCT02930174
View directory record Official record
Conditions
Spontaneous Ventilation
Interventions
noninvasive positive pressure ventilation
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Phase 2 Interventional Results available

B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial

NCT03136198
View directory record Official record
Conditions
Heart Failure, Heart Failure Acute, Acute Cardiac Pulmonary Edema, Acute Cardiac Failure
Interventions
LUS-guided strategy-of-care, Usual Care, Intravenous Loop Diuretic, Vasodilator, Non invasive Ventilation (NIV)
Other · Drug · Device
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
6
States / cities
Indianapolis, Indiana • Detroit, Michigan • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

External Nasal Dilator and Oxygen Therapy in Respiratory Failure

NCT02662387
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
External nasal dilator (END), High flow nasal cannula (HFNC)
Device · Other
Lead sponsor
Loma Linda University
Other
Eligibility
1 Day to 18 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Oct 22, 2026, 1:03 AM EDT
Terminated Not applicable Interventional

Polysomnography-directed Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)

NCT01363882
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Sleep study-guided adjustment of NIV, Standard initiation of NIV
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Evaluation Of The Total Face Mask For Emergency Application In Acute Respiratory Failure

NCT00686257
View directory record Official record
Conditions
Acute Respiratory Insufficiency
Interventions
Total face mask (interface for NPPV), Comfort full or RT040 oronasal mask (interface for NPPV)
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Oct 22, 2026, 1:03 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Detection of Cannabis Impairment With ISBRG's SpotLight-THC

NCT05276232
View directory record Official record
Conditions
Cannabis
Interventions
Cannabis(THC) inhaled
Drug
Lead sponsor
ISBRG Corp
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 22, 2026, 1:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)

NCT05713266
View directory record Official record
Conditions
COVID-19, Long COVID
Interventions
MouthLabTM
Device
Lead sponsor
Edith Nourse Rogers Memorial Veterans Hospital
Federal
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 22, 2026, 1:03 AM EDT
Not listed No phase listed Observational

Advanced Prediction of Respiratory Depression Episode With the Linshom Continuous Predictive Respiratory Sensor

NCT05804175
View directory record Official record
Conditions
Post Surgical Respiratory Failure, Respiratory Complication
Interventions
Linshom Continuous Predictive Respiratory Monitoring
Device
Lead sponsor
Linshom Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Ellicott City, Maryland • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2024 · Synced Oct 22, 2026, 1:03 AM EDT
Completed No phase listed Observational

Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)

NCT00537641
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2015 · Synced Oct 22, 2026, 1:03 AM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
27
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

NCT01355978
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Airflow Obstruction, Chronic, Chronic Obstructive Airway Disease, Chronic Obstructive Lung Disease
Interventions
Noninvasive Open Ventilation System
Device
Lead sponsor
Breathe Technologies, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
3
States / cities
Concord, California • San Diego, California • Ogden, Utah
Source: ClinicalTrials.gov public record
Updated Oct 12, 2016 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Phase 1 Interventional

Trial of Early Noninvasive Ventilation for Amyotrophic Lateral Sclerosis (ALS)

NCT00580593
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
BiPAP® S/T System, sham-NIPPV
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

NCT03214458
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Nasal high flow
Device
Lead sponsor
Temple University
Other
Eligibility
40 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Oct 22, 2026, 1:03 AM EDT
Withdrawn Phase 2 Interventional

Non Invasive Positive Pressure Ventilation in Status Asthmaticus

NCT01403428
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Noninvasive positive pressure ventilation
Other
Lead sponsor
Southern Illinois University
Other
Eligibility
1 Year to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 22, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Vector Engineering Clinical

NCT04725500
View directory record Official record
Conditions
COPD
Interventions
Auto-Titrating EPAP
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
40 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Youngstown, Ohio • Clairton, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Oct 22, 2026, 1:03 AM EDT
Recruiting Phase 3 Interventional

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

NCT02735707
View directory record Official record
Conditions
Community-acquired Pneumonia, Influenza, COVID-19
Interventions
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, P2Y12 inhibitor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Angiotensin Receptor Blockers, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
Drug · Other · Biological + 1 more
Lead sponsor
UMC Utrecht
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
11
States / cities
Jacksonville, Florida • Augusta, Georgia • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 22, 2026, 1:03 AM EDT