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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:42 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 161 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal Saline (NS) Clear all

Conditions: Shock, Septic
Interventions: Lactated Ringer, Normal saline; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 6 Months to 17 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Advanced Cancers, Dyspnea
Interventions: Fentanyl, Placebo, Walking Tests, Questionnaires; Drug · Other · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Prostate Cancer, Robotic Prostatectomy, Foley Catheter Discomfort
Interventions: Bupivacaine, Saline; Drug
Lead sponsor: Columbia University; Other
Eligibility: 40 Years to 80 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Photosensitive Epilepsy
Interventions: Valproic Acid, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 15 Years to 65 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 2
States / cities: Chesterfield, Missouri • Nashville, Tennessee

Conditions: Length of Labor, Second Stage of Labor, Intravenous Hydration of Labor
Interventions: Dextrose, Normal Saline; Other
Lead sponsor: MemorialCare Health System; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Allergy
Interventions: Neo-Synalar Cream, Sodium Lauryl Sulfate Aqueous Solution (0.40%), Saline; Drug · Other
Lead sponsor: Noah Rosenberg, MD; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 206 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Fairfield, New Jersey

Conditions: Ovarian Failure, Perimenopausal Disorder, Hormone Disturbance
Interventions: lipoaspiration harvest tSVF, Platelet Rich Plasma, Endovaginal Ultrasound, Cellular Isolation cSVF, Normal Saline (NS) .9% 10 mL Injection, emulsification tSVF; Procedure · Device · Drug
Lead sponsor: Black Tie Medical, Inc.; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Colchester, Vermont

Conditions: Benign Prostatic Hyperplasia
Interventions: Tranexamic Acid (IV), Placebo; Drug
Lead sponsor: Kaiser Permanente; Other
Eligibility: 45 Years and older · Male only
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Osteoarthritis, Pain
Interventions: Exparel, Femoral Nerve Block Bupivacaine, Toradol, Morphine Sulfate; Drug
Lead sponsor: The New England Baptist Hospital; Other
Eligibility: 18 Years to 73 Years
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prosthetic Joint Infection, Vancomycin, Joint Diseases
Interventions: Experimental Intraosseous vancomycin 500mg in 250 mL NS, Standard IV administration of vancomycin; Drug
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 19 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Healthy
Interventions: C-13 labeled Lysine, Normal saline; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 45 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Low Back Pain, Myofascial Pain Syndrome Lower Back
Interventions: Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below., Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below., Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.; Drug
Lead sponsor: Madigan Army Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Shock, Septic
Interventions: Lactated Ringer, Normal Saline, Plasma-lyte; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Months to 17 Years
Enrollment: 9,041 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 22
States / cities: Davis, California • Los Angeles, California • San Francisco, California + 19 more

Conditions: Breast Cancer, Breast Neoplasm
Interventions: Docetaxel - Dose A, Anastrozole, cyclophosphamide, Docetaxel - Dose B, Doxorubicin hydrochloride, Tamoxifen Citrate, Capecitabine - Dose B, Capecitabine - Dose A; Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease, Ketamine Infusion, Pain Management, Vaso-Occlusive Crises
Interventions: Sub-dissociative Ketamine Infusion, Normal Saline Placebo Infusion; Drug
Lead sponsor: Mohsen Saidinejad; Other
Eligibility: 5 Years to 20 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Torrance, California

Conditions: Pain
Interventions: Bipivacaine 0.5% with epinephrine, Normal Saline; Drug
Lead sponsor: Souza, Amanda, M.D.; Individual
Eligibility: 21 Years to 65 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Farmington Hills, Michigan

Conditions: Leukemia
Interventions: Clofarabine; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Suicide, Suicide Threat, Depression Severe
Interventions: Ketamine Hydrochloride, Normal saline; Drug
Lead sponsor: Naval Medical Center Camp Lejeune; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Marine Corps Base Camp Lejeune, North Carolina

Conditions: Septic Shock
Interventions: L-Carnitine, Normal Saline; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: Jackson, Mississippi • Charlotte, North Carolina

Conditions: Carcinoma, Hepatocellular
Interventions: PF-03446962, Best Supportive Care, Placebo; Drug · Other
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Multiple Sclerosis
Interventions: HB-adMSCs, Placebo; Biological · Drug
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Neonatal Encephalopathy, Birth Asphyxia
Interventions: Normal saline placebo, Erythropoietin; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: Up to 24 Hours
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 23
States / cities: Los Angeles, California • Palo Alto, California • San Francisco, California + 15 more

Conditions: Malaria
Interventions: PfSPZ Vaccine, PfSPZ Challenge (7G8) for CHMI, Normal Saline; Biological · Other
Lead sponsor: Sanaria Inc.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Lumbar Fusion Surgery
Interventions: Intraosseous Vancomycin, Intravenous Vancomycin; Drug
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Houston, Texas

Search by objective public record fields.

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study

Breakthrough Dyspnea Fentanyl Study in Cancer Patients

Dorsal Penile Block for Post-Robotic Prostatectomy Foley Discomfort

Effect of Valproic Acid Concentration on Photic Response

Effects of Rate and/or Presence of Dextrose on the Labor Course of Nulliparas

Neo-Synalar Modified 48 Hour Patch Test

Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF

Effect of Tranexamic Acid on Intraoperative Blood Loss in Patients Undergoing Aquablation

Femoral Nerve Block Compared to Exparel in Total Knee Replacement

Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

The Effect of Acute Lysine Administration on α-aminoadipic Acid (Sub-study)

Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

Bupivacaine Injections Into Uterosacral Ligaments During Robotic Assisted Total Hysterectomies

Clofarabine Bone Marrow Cytoreduction

Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department

L-Carnitine Administration in Early Sepsis

A Study To Evaluate The Efficacy And Safety of The Investigational Drug PF-03446962 (A Monoclonal Antibody With Antiangiogenic Features) In Combination With Best Supportive Care Versus Placebo Plus Best Supportive Care In Patients Affected By Recurrent Liver Cancer

Randomized Double-Blind Phase 2 Efficacy and Safety of Autologous HB-MSCs vs Placebo for Treatment of Multiple Sclerosis

High-dose Erythropoietin for Asphyxia and Encephalopathy

Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults

IO Vancomycin Spine