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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Normotensive Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)

NCT02406586
View directory record Official record
Conditions
Hypertension, Diabetes
Interventions
Salsalate, Carvedilol, Placebo, Intralipid 20%
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of 8 oz Fresh vs. Commercial Orange Juice on Blood Pressure In Normotensive Males Aged 18-59

NCT03691194
View directory record Official record
Conditions
Blood Pressure
Interventions
fresh orange juice, concentrated orange juice
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 59 Years · Male only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ventricular-Vascular Coupling in Heart Failure

NCT00207220
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
arterial tonometry, echocardiography
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 8, 2007 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mechanisms for Individual Differences in Hypertension in Obstructive Sleep

NCT03176732
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypertension
Interventions
Positive Airway Pressure
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 2, 2026, 9:13 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women

NCT03196141
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
StO2 and EndoPAT
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of High Blood Pressure and Antihypertensive Treatment on Brain Functioning in Children

NCT00178490
View directory record Official record
Conditions
Hypertension
Interventions
High blood pressure treatment
Drug
Lead sponsor
University of Rochester
Other
Eligibility
10 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2014 · Synced Sep 2, 2026, 9:13 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exercise, Hypertension, and Gut Dysbiosis in African Americans

NCT03897777
View directory record Official record
Conditions
Hypertension
Interventions
Exercise Training effect on Hypertension and Gut Dysbiosis
Behavioral
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
30 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Gut Butyrate and Blood Pressure in African Americans

NCT04415333
View directory record Official record
Conditions
Hypertension
Interventions
Sodium Butyrate 5 mmol, Sodium Butyrate 80 mmol
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
30 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Electronic Health Record-Based Clinical Decision Support to Improve Blood Pressure Management in Adolescents

NCT01760239
View directory record Official record
Conditions
Hypertension, Pre Hypertension, Obesity
Interventions
Clinical Decision Support (CDS)
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
10 Years to 17 Years
Enrollment
31,579 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Vinyasa Yoga on Vascular Function

NCT04226235
View directory record Official record
Conditions
Hypertension
Interventions
Yoga session
Behavioral
Lead sponsor
Texas State University
Other
Eligibility
20 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

High Resolution Phenotyping in Healthy Humans

NCT00943774
View directory record Official record
Conditions
Pressor Response, Baroreflex Sensitivity, Blood Pressure Variability, Heart Rate Variability, Arterial Catecholamines
Interventions
Physiological maneuvers
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2016 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Heart Rate and Blood Pressure Response During Exercise and Sexual Activity in Normotensive and Hypertensive Volunteers

NCT00143988
View directory record Official record
Conditions
Heart Rate, Blood Pressure
Interventions
Treadmill testing, Ambulatory Blood Pressure and Heart Rate Monitoring
Behavioral
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
40 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 23, 2009 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Production of Free Fatty Acids From Blood Triglycerides

NCT00911482
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Insulin Resistance, Dyslipidemias
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
35 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 6, 2012 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Phase 3 Interventional

TROPHY - Candesartan Cilexetil Long-term Hypertension Prevention Trial

NCT00227318
View directory record Official record
Conditions
Hypertension
Interventions
ATACAND
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
30 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
42
States / cities
Mobile, Alabama • Long Beach, California • Redondo Beach, California + 39 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2011 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Phase 2 Interventional

The Primary Objective of This Study is to Determine Whether MICARDIS® Improves Insulin Sensitivity in Overweight or Obese, Non-diabetic, Normotensive Subjects

NCT00146289
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
MICARDIS® (telmisartan)
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years to 65 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
8
States / cities
Los Angeles, California • San Diego, California • Westlake Village, California + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2013 · Synced Sep 2, 2026, 9:13 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Peripheral Vascular Effects of Sulfhydryl-containing Antihypertensive Pharmacotherapy on Microvessels in Humans

NCT03179163
View directory record Official record
Conditions
Hypertension,Essential
Interventions
Captopril Pill, Enalapril Pill, Hydrochlorothiazide
Drug
Lead sponsor
Penn State University
Other
Eligibility
40 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

OSA in Pregnant Women With Chronic HTN

NCT03230110
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pregnancy, Hypertension
Interventions
WP200U home sleep study device
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Sep 2, 2026, 9:13 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans

NCT02386293
View directory record Official record
Conditions
Hypertension, Obesity, Stress, Psychological, Blood Pressure
Interventions
Irbesartan, Placebo
Drug · Other
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Gut Organoid and Microbiome Interactions in Hypertension

NCT04497727
View directory record Official record
Conditions
Gut Inflammation, Hypertension
Interventions
Gene Expression
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 2, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT

NCT00958815
View directory record Official record
Conditions
Insulin Resistance, Atherosclerosis, Cardiovascular Disease, HIV/AIDS, HIV Infections
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
35 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 25, 2012 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes

NCT00738023
View directory record Official record
Conditions
Type 2 Diabetes, Hypertension
Interventions
Rosiglitazone, Normal saline 0.9%, Intralipid 20%
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 29, 2014 · Synced Sep 2, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

FFA Hypertension and Inflammation in Lean and Obese Subjects

NCT00721617
View directory record Official record
Conditions
Diabetes, Hypertension, Obesity
Interventions
Intralipid 20%, Normal Saline, Oral fat load
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Sep 2, 2026, 9:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

NCT05000515
View directory record Official record
Conditions
Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
High-resistance inspiratory muscle strength training, Aerobic exercise
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 2, 2026, 9:13 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Vascular Dysfunction in Hypertensive Postmenopausal Women

NCT03371823
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension
Interventions
Normotensive, Hypertensives
Other · Drug
Lead sponsor
University of Delaware
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 2, 2026, 9:13 PM EDT