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ClinicalTrials.gov public records Last synced Oct 19, 2026, 9:03 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 584 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: OCT Clear all
Recruiting Not applicable Interventional

OCT Eccentric Fixation and Amblyopia in Children

NCT05714449
View directory record Official record
Conditions
Amblyopia
Interventions
eye patch, After-image and MIT trainer
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
4 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

NCT06841575
View directory record Official record
Conditions
Eye Diseases, Retinal Disease, Glaucoma, Optic Nerve Diseases
Interventions
Auto-aligned OCT
Device
Lead sponsor
Duke University
Other
Eligibility
1 Month and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Completed Phase 1 Interventional

Phase 1b Study to Assess Safety, Tolerability, and Pharmacokinetics of ARCT-810 in Stable Adult Subjects With Ornithine Transcarbamylase Deficiency

NCT04442347
View directory record Official record
Conditions
Ornithine Transcarbamylase Deficiency
Interventions
ARCT-810, Placebo
Biological · Other
Lead sponsor
Arcturus Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
8
States / cities
Gainesville, Florida • Minneapolis, Minnesota • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2024 · Synced Oct 19, 2026, 9:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

NCT04505618
View directory record Official record
Conditions
Diabetic Retinopathy, Retinal Vein Occlusion, Hypertension,Essential, Retinal Vascular Disorder
Interventions
Swept-Source (SS) OCT Angiography, Spectral-Domain (SD) OCT Angiography, Fundus Imaging, Axial Length Measurement Device
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
1,050 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

OCT Vibrography for Biomechanical Properties of Tissues

NCT05759780
View directory record Official record
Conditions
Cornea, Skin Diseases, Gingival Diseases
Interventions
Optical imaging of the tissues
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Not listed No phase listed Observational

Home OCT Fluid Visualization Agreement Study

NCT04907409
View directory record Official record
Conditions
Neovascular Age-related Macular Degeneration
Interventions
Not listed
Lead sponsor
Notal Vision Inc.
Industry
Eligibility
55 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
7
States / cities
Marietta, Georgia • Lexington, Kentucky • Glen Burnie, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 19, 2026, 9:03 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

The Significance of Glucose Intolerance in the Pathogenesis of Idiopathic Axonal Polyneuropathy

NCT00228345
View directory record Official record
Conditions
Idiopathic Axonal Polyneuropathy, Abnormal OGTT
Interventions
Optical coherence tomography,Fluorescein angiography
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
50 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 19, 2026, 9:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optos P200TE Agreement and Precision Study

NCT03868462
View directory record Official record
Conditions
Retinal Disease, Glaucoma
Interventions
Optos P200TE, Predicate Device
Device
Lead sponsor
Optos, PLC
Industry
Eligibility
22 Years and older
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 19, 2026, 9:03 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial)

NCT01025232
View directory record Official record
Conditions
Age Related Macular Degeneration, Choroidal Neovascular Membrane, Subfoveal Neovascular Age-Related Macular Degeneration, Macular Degeneration, Wet Age-Related Macular Degeneration
Interventions
Ranibizumab
Drug
Lead sponsor
David M. Brown, M.D.
Other
Eligibility
50 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
2
States / cities
Houston, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2017 · Synced Oct 19, 2026, 9:03 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

NCT04565821
View directory record Official record
Conditions
Inflammatory Disease, Permeability; Increased, Crohn Disease, Inflammatory Bowel Diseases, Environmental Enteropathy
Interventions
IPD Probe via TNIT
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Completed Phase 3 Interventional Results available

Laser-Ranibizumab-Triamcinolone for Diabetic Macular Edema

NCT00444600
View directory record Official record
Conditions
Diabetic Retinopathy, Diabetic Macular Edema
Interventions
Triamcinolone Acetonide + laser, Ranibizumab + laser, Sham injection + laser, Ranibizumab + deferred laser
Drug
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
18 Years and older
Enrollment
691 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
50
States / cities
Artesia, California • Beverly Hills, California • Irvine, California + 42 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 19, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Protective Genetic Factors Against Neurological Diseases

NCT03914599
View directory record Official record
Conditions
Neurological Disorder, Healthy Control
Interventions
Not listed
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 100 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Oct 19, 2026, 9:03 PM EDT
Withdrawn Phase 4 Interventional

Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple Therapy

NCT04075136
View directory record Official record
Conditions
Exudative Age Related Macular Degeneration
Interventions
Ranibizumab, Photodynamic laser treatment (PDT), Triamcinolone Acetonide, verteporfin
Drug · Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 19, 2026, 9:03 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

An Age-Stratified Data Collection Study to Establish a Normative Database Using the 3D Optical Coherence Tomography 3D OCT-1000 Mark II

NCT01027936
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Topcon Corporation
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
6
States / cities
La Jolla, California • Overland Park, Kansas • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 19, 2026, 9:03 PM EDT
Enrolling by invitation Not applicable Interventional

Study to Determine the Clinical Significance of Intravascular OCT-NIRAF

NCT06374498
View directory record Official record
Conditions
Cardiovascular Diseases, Coronary Artery Disease
Interventions
OCT-NIRAF, LUMISIGHT Injection, OCT-NIRAF following LUMISIGHT Injection
Device · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Withdrawn No phase listed Observational

Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer

NCT00581503
View directory record Official record
Conditions
Lung Cancer, Pleural Cancer, Prostate Cancer
Interventions
diagnostic
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
2
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 19, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using Optical Coherence Tomography to Capture Retinal Microvascular Changes Associated With Multiple Sclerosis

NCT01596881
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Oct 19, 2026, 9:03 PM EDT
Completed Phase 2 Interventional

Prospective OCT Study With Lucentis for Neovascular AMD (PrONTO Study)

NCT00344227
View directory record Official record
Conditions
Neovascular Age-Related Macular Degeneration
Interventions
Lucentis (Ranibizumab)
Drug
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2006 · Synced Oct 19, 2026, 9:03 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

TIV and High Dose TIV in Subjects With Rheumatoid Arthritis

NCT01436370
View directory record Official record
Conditions
Influenza
Interventions
Trivalent inactivated influenza vaccine
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 64 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 24, 2014 · Synced Oct 19, 2026, 9:03 PM EDT
Active, not recruiting No phase listed Observational

Long Term Follow Up to Evaluate DTX301 in Adults With Late-Onset OTC Deficiency

NCT03636438
View directory record Official record
Conditions
Ornithine Transcarbamylase (OTC) Deficiency
Interventions
No Intervention
Other
Lead sponsor
Ultragenyx Pharmaceutical Inc
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Timeline
2018 – 2029
U.S. locations
4
States / cities
Aurora, Colorado • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 19, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Opioid Sparing Pain Management Strategy

NCT04269109
View directory record Official record
Conditions
Cardiac Surgical Procedures
Interventions
Multi-modal Opioid Sparing Pain Management Protocol
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Oct 19, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Functionally Validated Structural Endpoints for Early AMD

NCT04112667
View directory record Official record
Conditions
Age-related Macular Degeneration, Aging
Interventions
Normal Macular Health, Early Macular Degeneration, Young Normals
Other
Lead sponsor
Cynthia Owsley
Other
Eligibility
20 Years and older
Enrollment
556 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 19, 2026, 9:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium

NCT05835141
View directory record Official record
Conditions
Corneal Endothelium
Interventions
OCT Imaging
Other
Lead sponsor
University of Southern California
Other
Eligibility
40 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 19, 2026, 9:03 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-1)

NCT02785029
View directory record Official record
Conditions
Glaucoma
Interventions
OCT
Device
Lead sponsor
Heidelberg Engineering GmbH
Industry
Eligibility
18 Years to 90 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
8
States / cities
La Jolla, California • Santa Monica, California • Mt. Dora, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 19, 2026, 9:03 PM EDT