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ClinicalTrials.gov public records Last synced Nov 5, 2026, 1:24 AM EST

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Showing 1129–1152 of 21,027 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ONE Clear all
Completed Not applicable Interventional

Automatic Prosthetic Foot Stiffness Modulation to Improve Balance

NCT06711588
View directory record Official record
Conditions
Lower Limb Amputation Below Knee
Interventions
As-prescribed stiffness, Two categories stiffer than the as-prescribed stiffness, Two categories less stiff than the as-prescribed stiffness
Device
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Active, not recruiting Phase 1 Interventional

Up-front CART-BCMA With or Without huCART19 in High-risk Multiple Myeloma

NCT03549442
View directory record Official record
Conditions
Multiple Myeloma
Interventions
BCMA CART + huCART19, CART BCMA or CART BCMA + huCART19, Single-dose infusion of CART BCMA or CART BCMA + huCART19
Biological
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2036
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

A School Health Center Intervention to Increase Adolescent Vaccination

NCT01595542
View directory record Official record
Conditions
Immunization Program, School Health Services, HPV Vaccines
Interventions
Modified Vaccine Consent Form
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Not listed
Enrollment
3,417 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2014 · Synced Nov 5, 2026, 1:24 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Identification and Analysis of Immunomodulatory Molecules in Patients With Hematologic Disorders and Healthy Volunteers

NCT00223483
View directory record Official record
Conditions
Hematologic Diseases, Healthy Volunteers
Interventions
Isolation of genomic DNA
Genetic
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2021
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Multiple Ascending Doses of AMG 139 in Healthy and Crohn's Disease Subjects

NCT01258205
View directory record Official record
Conditions
Crohn's Disease
Interventions
AMG 139
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
4
States / cities
Berlin, New Jersey • Stony Brook, New York • Oklahoma City, Oklahoma + 1 more
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Nov 5, 2026, 1:24 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers

The Pittsburgh Study Early Childhood

NCT05444205
View directory record Official record
Conditions
Child Development, Child Language, Child Behavior Problem, Parenting, Parent Child Abuse
Interventions
Text4Baby or Bright by Text Referral, Nurture Program Warm Referral, Video Interaction Project, Family Check-UP, Smart Beginnings, Healthy Families America Warm Referral, Family Center Warm Referral
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Up to 6 Years
Enrollment
2,546 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
5
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Active, not recruiting Not applicable Interventional

Mobility in Daily Life and Falls in Parkinson's Disease: Potential for Rehabilitation

NCT04897256
View directory record Official record
Conditions
Parkinson Disease
Interventions
TURN-IT exercise program
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
55 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Nov 5, 2026, 1:24 AM EST
Completed Not applicable Interventional

Reducing HIV Risk in Urban Women: Soap Opera Videos on Video-Capable Cell Phones

NCT03330522
View directory record Official record
Conditions
HIV/AIDS, Sexual Behavior, Woman's Role, Risk Behavior
Interventions
Love, Sex, & Choices video series, Messages in text
Other
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Nov 5, 2026, 1:24 AM EST
Completed Not applicable Interventional

Promoting the Use of CPAP Therapy Among OSA Patients

NCT04372329
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP4HealthySleep system
Behavioral
Lead sponsor
Sarah Alismail
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Claremont, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Nov 5, 2026, 1:24 AM EST
Active, not recruiting Not applicable Interventional

Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication

NCT07147023
View directory record Official record
Conditions
Advanced Cancer, Cancer, End of Life
Interventions
LLM SIC Summary Email
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 1 Interventional

Palliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers

NCT05220046
View directory record Official record
Conditions
Pancreas Cancer, Biliary Tract Cancer, Psychological Distress, Gastrointestinal Cancer
Interventions
Psilocybin
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.

NCT01053403
View directory record Official record
Conditions
MDMA Discontinuation Syndrome
Interventions
3,4-methylenedioxymethamphetamine or Placebo
Drug
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 31, 2013 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder

NCT03375203
View directory record Official record
Conditions
Insomnia Disorders
Interventions
Placebo, JNJ-42847922, 5 mg, JNJ-42847922, 10 mg, JNJ-42847922, 20 mg, Zolpidem
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
24
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Anaheim, California + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 3 Interventional

An Eight-week Study Evaluating the Efficacy of a 100mg Dose of Saredutant Once Daily, in Elderly Patients With Major Depressive Disorder

NCT00415142
View directory record Official record
Conditions
Depressive Disorder
Interventions
saredutant (SR48968), placebo, escitalopram
Drug
Lead sponsor
Sanofi
Industry
Eligibility
60 Years to 64 Years
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2016 · Synced Nov 5, 2026, 1:24 AM EST
Terminated Phase 1 Interventional

A Safety and Efficacy Study of INC280 Alone, and in Combination With Erlotinib, Compared to Chemotherapy, in Advanced/Metastatic Non-small Cell Lung Cancer Patients With EGFR Mutation and cMET Amplification

NCT02468661
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
INC280 single agent, erlotinib
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
5
States / cities
Los Angeles, California • Orange, California • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Nov 5, 2026, 1:24 AM EST
Completed No phase listed Observational

Validation of Handheld Ultrasound Devices in Rheumatology

NCT06580886
View directory record Official record
Conditions
Psoriatic Arthritis
Interventions
Ultrasound
Device
Lead sponsor
Ottawa Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 30, 2024 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 2 Interventional

The Effects of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Blepharitis During a Two-Week Treatment Period

NCT00892970
View directory record Official record
Conditions
Blepharitis
Interventions
Azithromycin ophthalmic solution, 1%, Placebo
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
33
States / cities
Little Rock, Arkansas • Artesia, California • Azusa, California + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2011 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 2 Interventional Results available

Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell Lymphoma

NCT03623373
View directory record Official record
Conditions
Mantle Cell Lymphoma
Interventions
Bendamustine, Rituximab, Acalabrutinib, Cytarabine, Leukapheresis, Peripheral blood, Oral rinse, Bone marrow collection
Drug · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Breathwork Training Reduces Anxiety In Outpatient Gastrointestinal Procedures

NCT07647341
View directory record Official record
Conditions
Anxiety
Interventions
paced breathwork
Behavioral
Lead sponsor
Calm and Sense Technologies LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Jupiter, Florida
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Completed Phase 2 Interventional

Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria

NCT05570305
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Zibotentan, Dapagliflozin, Placebo, Dapagliflozin and Zibotentan
Drug
Lead sponsor
University Medical Center Groningen
Other
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Nov 5, 2026, 1:24 AM EST
Terminated Phase 1Phase 2 Interventional Results available

The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes

NCT01832766
View directory record Official record
Conditions
Schizophrenia
Interventions
Dronabinol, Placebo Comparator
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2015 · Synced Nov 5, 2026, 1:24 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Sit-Stand Workstations on Physical Activity in Sedentary Office Workers

NCT01863056
View directory record Official record
Conditions
Sedentary
Interventions
Sit-Stand Desk
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 7, 2023 · Synced Nov 5, 2026, 1:24 AM EST
Recruiting No phase listed Observational Accepts healthy volunteers

Pancreatic Cancer Early Detection Consortium

NCT04970056
View directory record Official record
Conditions
Pancreas Cancer, Pancreas Cyst, Pancreatic Ductal Adenocarcinoma, Genetic Predisposition
Interventions
Not listed
Lead sponsor
Arbor Research Collaborative for Health
Other
Eligibility
18 Years to 90 Years
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
46
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Burbank, California + 39 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Nov 5, 2026, 1:24 AM EST
Not yet recruiting Phase 1 Interventional

211At-MABG in Adults With Advanced Neuroendocrine Cancers

NCT07661420
View directory record Official record
Conditions
Pheochromocytoma, Paraganglioma, Neuroendocrine Tumors, Medullary Thyroid Cancer, Bronchial Carcinoid, Gastroenteropancreatic Neuroendocrine Neoplasm
Interventions
1 MBq/k of 211At-MABG Fractionated, 2 MBq/k1 of 211At-MABG Fractionated, 4 MBq/k of 211At-MABG Fractionated
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Nov 5, 2026, 1:24 AM EST