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Conditions: Headache, Pregnancy Related, Occipital Nerve Block
Interventions: Occipital Nerve Block; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 16 Years to 60 Years · Female only
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Denture Retention
Interventions: Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive; Device · Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Peripheral Vascular Diseases, Arterial Occlusive Diseases, Ischemia, Graft Occlusion, Vascular, Hyperplasia
Interventions: CGT003 (E2F Duplex Decoy); Drug
Lead sponsor: Anesiva, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 116
States / cities: Birmingham, Alabama • Mobile, Alabama • Tucson, Arizona + 61 more

Conditions: Hepatocellular Cancer
Interventions: Oncozene-DEB-TACE; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Alcohol Dependence, PTSD
Interventions: Propranolol, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Renal Failure Congenital, Congenital Renal Anomaly Nos, Renal Agenesis and Dysgenesis, Lower Urinary Tract Obstructive Syndrome
Interventions: Lactated Ringers Solution for Injection; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Ischemic Stroke From Large Vessel Occlusion
Interventions: intra-arterial tenecteplase administration; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hip Fracture
Interventions: UFNB (Ultrasound guided femoral nerve block), UFIB (Ultrasound Guided Fascia Iliaca Compartment Block), IVMS (IV Morphine); Procedure · Drug
Lead sponsor: Antonios Likourezos; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: Blinatumomab; Drug
Lead sponsor: Dorothy Sipkins, MD, PhD; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 3
States / cities: Tampa, Florida • Durham, North Carolina • Winston-Salem, North Carolina

Conditions: Uncontrolled Postoperative Pain
Interventions: 0.375% ROPIVACAINE, placebo; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 40 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Endometriosis
Interventions: Bupivacaine Hydrochloride, Normal saline; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Native and Valve in Valve Aortic Valve Failure
Interventions: ASHI_INTECC Astato XS 20 0.014 guidewire; Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 21 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 4
States / cities: Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 1 more

Conditions: Peripheral Arterial Disease
Interventions: Orbital Circumferential Atherectomy; Device
Lead sponsor: Cardio Flow, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 13
States / cities: Altamonte Springs, Florida • Fort Lauderdale, Florida • Gainesville, Florida + 10 more

Conditions: Social Behavior Disorders, Neurodevelopmental Disorders
Interventions: Melillo Method; Procedure
Lead sponsor: Life University; Other
Eligibility: 8 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Roodhouse, Illinois

Conditions: Osteoarthritis, Knee
Interventions: Genicular nerve radiofrequency ablation, Pain Management Radiofrequency Kit; Procedure · Device
Lead sponsor: Millennium Pain Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 3
States / cities: Bloomington, Illinois • Decatur, Illinois • Peoria, Illinois

Conditions: Congenital Diaphragmatic Hernia
Interventions: Fetal Treatment arm (FETO Group); Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Rib Fracture Multiple
Interventions: Serratus Anterior Plane Block (SAPB), Standard Analgesic Medications; Procedure · Drug
Lead sponsor: WellSpan Health; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: York, Pennsylvania

Conditions: Quadriceps Atrophy, ACL Reconstruction
Interventions: Blood flow restriction, Physical therapy; Device · Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 14 Years to 55 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Transcranial Electric Stimulation
Interventions: TES-TI with hdEEG; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Neuromyelitis Optica
Interventions: High Frequency Impulse Therapy, High Frequency Impulse Therapy - Sham; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Central Retinal Vein Occlusion, Proliferative Diabetic Retinopathy
Interventions: Intravitreal Aflibercept Injection; Drug
Lead sponsor: Ophthalmic Consultants of Boston; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HPV-Related Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
Interventions: IMRT (Intensity Modulated Radiotherapy), Pembrolizumab, Cisplatin, ISA101b; Radiation · Drug · Biological
Lead sponsor: Dan Zandberg; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
Interventions: General anesthetic, SA + ESP; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 80 Years
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Temporomandibular Disorders (TMD)
Interventions: Standard care, Physical Therapy (PT); Other
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

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Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine

A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers

Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

A Pilot Study of "OncozeneTM" Microspheres for Intra-arterial Delivery of Doxorubicin

Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence

Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia

Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy

Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients

Blincyto Amgen Acrotech BioPharma PH2 Blincyto Marqibo R/R Philadelphi CD19+ ALL

Can Post-operative TAP Block Improve Quality of Recovery After C-sections in Patients on Methadone Maintenance?

Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis

Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation

Evaluation of the FreedomFlow™ Orbital Atherectomy System to Treat Peripheral Artery Disease

The Effects of the Melillo Method® on Biopsychosocial Outcomes in School-Age Children

Efficacy of Cooled and Monopolar Radiofrequency Ablation of the Geniculate Nerves for the Treatment of Chronic Osteoarthritic Knee Pain

North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia

Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?

Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking

High Frequency Impulse Therapy for Neuropathic Pain in NMOSD

Impact of Intravitreal Aflibercept Injections on Capillary Non-Perfusion

HPV-16 Vaccination and Pembrolizumab Plus Cisplatin for "Intermediate Risk" HPV-16-associated Head and Neck Squamous Cell Carcinoma

GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries

The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders