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ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:43 PM EDT

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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Off Pump CABG Clear all
Completed Phase 3 Interventional Results available

Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass

NCT00032630
View directory record Official record
Conditions
Ischemic Heart Disease
Interventions
Coronary artery bypass - on-pump, Coronary artery bypass - off-pump
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
2,203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
17
States / cities
Palo Alto, California • San Francisco, California • Sepulveda, California + 14 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Oct 17, 2026, 1:43 PM EDT
Completed No phase listed Observational Results available

Hybrid Revascularization Observational Study

NCT01121263
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Atlanta, Georgia • Baltimore, Maryland • Boston, Massachusetts + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Oct 17, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

NCT05427370
View directory record Official record
Conditions
Coronary Artery Disease, Heart Failure Systolic
Interventions
Revascularization by PCI, Revascularization by CABG
Procedure
Lead sponsor
Sunnybrook Health Sciences Centre
Other
Eligibility
18 Years and older
Enrollment
754 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
Los Angeles, California • New Haven, Connecticut • Louisville, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 17, 2026, 1:43 PM EDT
Completed No phase listed Observational

Comparison of the Risk of Stroke With On- Versus Off-Pump Coronary Artery Bypass Grafting

NCT00046410
View directory record Official record
Conditions
Coronary Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 17, 2026, 1:43 PM EDT
Active, not recruiting No phase listed Observational

Impella Supported OPCABG

NCT04339452
View directory record Official record
Conditions
Ischemic Cardiomyopathy
Interventions
Impella 5.5 with SmartAssist Supported OPCABG
Device
Lead sponsor
Lucian Archambault Durham III
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 17, 2026, 1:43 PM EDT
Completed No phase listed Observational

Comparing Blood Loss, RBC Transfusions and Inflammatory Marker Changes Among Methods of CPB

NCT01083914
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2013 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Not applicable Interventional Results available

Hybrid Coronary Revascularization Trial

NCT03089398
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Hybrid Coronary Revascularization (isolated LIMA-LAD), Hybrid Coronary Revascularization (PCI), Percutaneous Coronary Intervention
Procedure · Device
Lead sponsor
Emilia Bagiella
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
39
States / cities
Long Beach, California • Los Angeles, California • Stanford, California + 31 more
Source: ClinicalTrials.gov public record
Updated May 23, 2025 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

NCT02100722
View directory record Official record
Conditions
Coronary Disease, Coronary Stenosis
Interventions
FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
13
States / cities
Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Not applicable Interventional

A Single Center Clinical Evaluation of Same Sitting Hybrid Revascularization: Robotic Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease

NCT00928356
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Hybrid CABG/PCI, Off Pump CABG
Procedure
Lead sponsor
Pinnacle Health Cardiovascular Institute
Network
Eligibility
Not listed
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB

NCT00073593
View directory record Official record
Conditions
Cardiac Surgery, Coronary Artery Bypass Surgery
Interventions
Bivalirudin, Heparin, Protamine
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 10, 2011 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Not applicable Interventional

SMART Trial Longitudinal Follow-Up:Off-Pump Versus On-Pump Coronary Artery Bypass Surgery

NCT00209053
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Coronary Artery Bypass
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 16, 2013 · Synced Oct 17, 2026, 1:43 PM EDT
Terminated Phase 1 Interventional

Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery

NCT00990795
View directory record Official record
Conditions
Cardiac Surgical Procedures
Interventions
cyclosporine, saline solution
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2010 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Phase 3 Interventional

Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)

NCT00073580
View directory record Official record
Conditions
Thrombocytopenia, Thrombosis, Cardiac Disease, Coronary Artery Bypass Surgery
Interventions
Angiomax (bivalirudin) anticoagulant
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 30, 2018 · Synced Oct 17, 2026, 1:43 PM EDT
Terminated Not applicable Interventional Results available

The Left Ventricular Assist Device (LVAD) Off or On Pump Implantation Study

NCT04219618
View directory record Official record
Conditions
Heart Failure, LVAD
Interventions
Off-Pump, On-Pump
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Stroke Study: Operative Strategies to Reduce Cerebral Embolic Events During Coronary Artery Bypass Surgery

NCT01502683
View directory record Official record
Conditions
Stroke
Interventions
No aortic clamping, partial occluding clamp, single cross clamp, cross clamp and partial occluding clamp
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 17, 2026, 1:43 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Assessment of Platelet Function in Patients Undergoing Open Heart Surgery

NCT05441358
View directory record Official record
Conditions
Coronary Artery Bypass Grafting, Open Heart Surgery, Aortic Surgery or Redo Surgery, On-pump Double or Triple Valve Procedures
Interventions
Open Heart Surgery
Procedure
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 17, 2026, 1:43 PM EDT
Completed Phase 3 Interventional

Hetastarch and Bleeding Complications After Off-Pump Coronary Bypass Surgery

NCT00307138
View directory record Official record
Conditions
Postoperative Hemorrhage
Interventions
hetastarch
Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 80 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated May 22, 2006 · Synced Oct 17, 2026, 1:43 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients

NCT02338947
View directory record Official record
Conditions
Frail Elderly, Coronary Artery Disease
Interventions
Off-pump coronary-artery bypass grafting, On-pump coronary-artery bypass grafting
Other
Lead sponsor
University of Sao Paulo General Hospital
Other
Eligibility
60 Years and older
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 17, 2026, 1:43 PM EDT