- Conditions
- Delirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane Block
- Interventions
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring, Generalized Anxiety Disorder 7-item (GAD-7) scale, Numerical Rating Score (NRS), PROMIS-Pain Interference, Oswestry Disability Index (ODI), Saint Louis University Mental Status Examination (SLUMs), Delirium Rating Scale-Revised-98 (DRS), Telephone Interview for Cognitive Status - Modified (TICS-M), Opioid Equivalents measured by Morphine Milligram Equivalents (MME), Patient Health Questionnaire depression scale (PHQ-8), Pain Catastrophizing, Fear Avoidance Beliefs Questionnaire (FABQ), Opioid Side Effects and Likeability Questionnaire, Daily Pain Trajectory, Tampa Scale of Kinesiophobia, Quality of Recovery 15
- Drug · Diagnostic Test · Other
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
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Showing 25–48
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Acute Pain, Pain, Postoperative
- Interventions
- Elbow Fracture Fixation
- Procedure
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- Up to 17 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Acute Pain
- Interventions
- ANI-guided opioid administration, Standard opioid administration
- Device · Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Laparoscopic Sleeve Gastrectomy, Subcostal Transversus Abdominis Plane Block
- Interventions
- Saline, Bupivacaine
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Pain, Postoperative
- Interventions
- Gabapentin, Acetaminophen, Celecoxib, Ketorolac, Paracervical block with ropivacaine, Local anesthetic injection with ropivacaine at abdominal laparoscopic port sites, Hydromorphone, Oxycodone
- Drug · Procedure
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 25 Years to 90 Years · Female only
- Enrollment
- 68 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Williamsville, New York
- Conditions
- Joint Disease, Pain, Acute, Pain, Chronic
- Interventions
- Cymbalta, Placebo
- Drug · Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cancer
- Interventions
- propofol general anesthesia, Sevoflurane
- Procedure · Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 85 Years · Female only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Ketamine Adverse Reaction, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Complication of Labor and/or Delivery
- Interventions
- Ketamine, Placebo
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 60 Years · Female only
- Enrollment
- 188 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- ACL, Opioid Use, Cryotherapy Effect, Vibration; Exposure, Pain, Postoperative
- Interventions
- VibraCool mechanical stimulation and neuromodulatory therapeutic device, Cryocompression (Game Ready, Bregs) device, Standard ice packs
- Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- Not listed
- Enrollment
- 130 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Pain Management, Opioid Consumption
- Interventions
- Placebo, Oxycodone 5 mg, Multimodal Non-Opioid Analgesia
- Drug · Other
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Postoperative Pain
- Interventions
- Methadone, Hydromorphone
- Drug
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2018
- U.S. locations
- 1
- States / cities
- Evanston, Illinois
- Conditions
- Descending Aortic Dissection, Postoperative Pain, Thoracoabdominal Aortic Aneurysm
- Interventions
- Saline, Ketamine
- Drug
- Lead sponsor
- Eric Johnson
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Post-operative Pain, Acute, Cesarean Section, Opioid Use Disorder, Opioids; Harmful Use
- Interventions
- Auricular percutaneous nerve field stimulator, Sham auricular percutaneous nerve field stimulator
- Device
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 18 Years to 55 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Falls Church, Virginia
- Conditions
- ACL Tear, Post Operative Pain
- Interventions
- Iovera, Celecoxib, Acetaminophen, Oxycodone, Tramadol, Bupivacaine Hydrochloride, Acetaminophen 500Mg Cap
- Device · Drug
- Lead sponsor
- Matthew Varacallo
- Other
- Eligibility
- 15 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- DuBois, Pennsylvania
- Conditions
- Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Interventions
- IV Acetaminophen, Standard of Care
- Drug
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 3
- States / cities
- Manhasset, New York • New Hyde Park, New York • Syosset, New York
- Conditions
- Bone Fracture, Opioid Use, Opioid Dependence
- Interventions
- SOC Pain Management, Early US Guided Nerve Block Administration
- Other · Procedure
- Lead sponsor
- Wayne State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 2
- States / cities
- Detroit, Michigan
- Conditions
- Pain, Referred
- Interventions
- Bupivacaine, Morphine, Fentanyl, Epinephrine, Saline solution
- Drug · Other
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 17 Years to 40 Years · Female only
- Enrollment
- 26 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Scoliosis, Kyphosis
- Interventions
- Methadone
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Ambulatory Hand Surgery
- Interventions
- Patient education regarding indications for opioid use and side effects of opioid use after hand surgery, Standard of care post-operative counseling
- Behavioral · Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Orthopaedic Trauma, Chronic Opioid Use
- Interventions
- Ketorolac Injection, Standard of Care (SOC) Multimodal Analgesia
- Drug · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 458 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Nashville, Tennessee
- Conditions
- Thyroidectomy, Parathyroidectomy, Opioid Use, Pain, Postoperative
- Interventions
- Quality improvement bundle
- Other
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Opioid Use Disorder
- Interventions
- Opioid-free anesthesia, Opioid-based anesthesia
- Drug
- Lead sponsor
- Jacques E. Chelly
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Heart Diseases
- Interventions
- Lidocaine, Unrestricted Fentanyl, Ketamine, Precedex, Duramorph
- Drug
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Anesthesia, Block
- Interventions
- Erecto Spinae nerve block, Multimodal Analgesia
- Procedure
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 78 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- The Bronx, New York