- Conditions
- Obstructive Sleep Apnea, Down Syndrome
- Interventions
- Atomoxetine and Oxybutynin (ato-oxy)
- Drug
- Lead sponsor
- University of Arizona
- Other
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
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Showing 1–14
of 14
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Obstructive Sleep Apnea
- Interventions
- AD109, Atomoxetine, R-oxybutynin, Placebo, Digit System Substitution Test
- Drug · Diagnostic Test
- Lead sponsor
- Apnimed
- Industry
- Eligibility
- 25 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 7
- States / cities
- Little Rock, Arkansas • Pomona, California • New Haven, Connecticut + 4 more
- Conditions
- Healthy Volunteers
- Interventions
- oxybutynin chloride immediate-release, oxybutynin chloride topical gel, placebo
- Drug · Other
- Lead sponsor
- Watson Pharmaceuticals
- Industry
- Eligibility
- 60 Years to 79 Years
- Enrollment
- 153 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2008
- U.S. locations
- 6
- States / cities
- Tucson, Arizona • National City, California • Maitland, Florida + 3 more
- Conditions
- Overactive Bladder
- Interventions
- onaBoNT-A, Oxybutynin ER
- Drug
- Lead sponsor
- Christopher Patrick Smith
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 2
- States / cities
- Houston, Texas
- Conditions
- Obstructive Sleep Apnea, Sleep-disordered Breathing
- Interventions
- Combination device and drug: Unilateral hypoglossal nerve stimulation & atomoxetine-plus-oxybutynin (HGNS+AtoOxy), Unilateral hypoglossal nerve stimulation (HGNS), active comparator condition, Atomoxetine-plus-oxybutynin (80/5 mg) (AtoOxy), active comparator condition, Placebo; placebo comparator condition
- Other · Device · Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Overactive Bladder Syndrome, Neuropathic Bladder
- Interventions
- Oxybutynin Transdermal Patch, Oral Oxybutynin
- Drug
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 4 Years to 8 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Urinary Bladder Overactive, Overactive Bladder, Urinary Bladder Diseases, Urologic Diseases
- Interventions
- mirabegron, antimuscarinic medication
- Drug
- Lead sponsor
- Astellas Scientific & Medical Affairs, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,524 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 75
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 56 more
- Conditions
- Urinary Urge Incontinence
- Interventions
- Oxybutynin extended release, Posterior Tibial Nerve Stimulation, Placebo
- Drug · Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Raleigh, North Carolina
- Conditions
- Obstructive Sleep Apnea (OSA)
- Interventions
- Positive airway pressure (PAP) therapy, Sleep dental device, Atomoxetine-oxybutynin
- Device · Drug
- Lead sponsor
- Sairam Parthasarathy
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2032
- U.S. locations
- 4
- States / cities
- Tucson, Arizona • Redwood City, California • Miami, Florida + 1 more
- Conditions
- Detrusor Hyperreflexia
- Interventions
- Oxybutynin
- Drug
- Lead sponsor
- Watson Pharmaceuticals
- Industry
- Eligibility
- 6 Years to 15 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 23
- States / cities
- Little Rock, Arkansas • Orange County, California • San Diego, California + 20 more
- Conditions
- Sleep Apnea
- Interventions
- Atomoxetine, Oxybutynin, Placebo
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 117 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Sialorrhoea
- Interventions
- oxybutynin and clonidine oral solution treatment A, oxybutynin and clonidine oral solution treatment B, oxybutynin and clonidine oral solution treatment C, oxybutynin and clonidine oral solution treatment D
- Drug
- Lead sponsor
- Orient Pharma Co., Ltd.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Bingham Farms, Michigan
- Conditions
- Hot Flashes
- Interventions
- Fezolinetant, Paroxetine, Citalopram, Escitalopram, Desvenlafaxine, Venlafaxine, Gabapentin, Clonidine, Pregabalin, Oxybutynin, Any other SSRI/SNRI not already specified, Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above
- Drug
- Lead sponsor
- Astellas Pharma Global Development, Inc.
- Industry
- Eligibility
- 40 Years to 75 Years · Female only
- Enrollment
- 999 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 48
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Lomita, California + 39 more
- Conditions
- Kidney Calculi, Kidney Diseases, Nephrolithiasis, Urolithiasis, Ureteral Diseases, Ureteral Calculi
- Interventions
- Methocarbamol, Oxybutynin
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois