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ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:47 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 618 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Oral Supplement Clear all

Conditions: Delirium
Interventions: Melatonin, Placebo; Dietary Supplement · Other
Lead sponsor: Scripps Health; Other
Eligibility: 65 Years to 100 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Basic Science, Intervention Studies, Biomarker Discovery
Interventions: Oral Lozenges (Tradename pHossident), Water additive (Tradename Protektin); Dietary Supplement
Lead sponsor: Delta Dental of Minnesota Foundation; Other
Eligibility: 18 Years to 80 Years
Enrollment: 595 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Bladder Cancer
Interventions: Genistein, Sugar pill; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Osteoporosis, Prostate Cancer
Interventions: Calcium, Zoledronic acid, radiation therapy, LHRH, Vitamin D; Dietary Supplement · Radiation · Drug
Lead sponsor: Radiation Therapy Oncology Group; Network
Eligibility: 18 Years and older · Male only
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2014
U.S. locations: 80
States / cities: Chico, California • Los Angeles, California • Pomona, California + 66 more

Conditions: Acne Vulgaris, Acneiform Eruptions, Skin Diseases, Sebaceous Gland Diseases
Interventions: Probiotic, Oral herbal powder supplement; Other · Dietary Supplement
Lead sponsor: Integrative Skin Science and Research; Industry
Eligibility: 12 Years to 45 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Mild Cognitive Impairment (MCI), Cognitive Dysfunction, Cognitive Disorder, Memory Problems
Interventions: Sabroxy™ (Oroxylum indicum extract), Placebo; Dietary Supplement · Other
Lead sponsor: SF Research Institute, Inc.; Network
Eligibility: 60 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Neural Response in Caudate, Weight Loss Trial, Impulsivity
Interventions: PhosphoLean, Placebo; Dietary Supplement
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Sleep, Mood, Cognitive Performance
Interventions: Proprietary Spearmint Extract Blend, Control; Dietary Supplement · Other
Lead sponsor: University of Arizona; Other
Eligibility: 22 Years to 50 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Type 2 Diabetes, Chronic Kidney Diseases
Interventions: Oral sodium suppression test, Saline suppression test, Captopril suppression test, Dexamethasone suppression test, Cosyntropin stimulation test; Diagnostic Test
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hypovitaminosis D
Interventions: Standing Phototherapy Kiosk, D3 Oral supplement; Device · Dietary Supplement
Lead sponsor: Madigan Army Medical Center; Federal
Eligibility: 18 Years to 69 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Anemia, Iron Deficiency (Without Anemia), Iron Absorption
Interventions: marine-based heme iron; Dietary Supplement
Lead sponsor: Nutraceuticals Research Institute; Other
Eligibility: 21 Years to 42 Years · Female only
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Huntsville, Alabama

Conditions: Prediabetes, Healthy (Controls)
Interventions: Ketone Monoester (KE), Placebo; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 60 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Metabolic Syndrome
Interventions: Ketone Ester Supplement, Placebo; Dietary Supplement · Other
Lead sponsor: University of Southern Mississippi; Other
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Hattiesburg, Mississippi

Conditions: Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Joint Cartilage Turnover
Interventions: NEM® brand eggshell membrane, Placebo; Dietary Supplement
Lead sponsor: ESM Technologies, LLC; Industry
Eligibility: 40 Years to 75 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Springfield, Missouri

Conditions: Healthy Adult
Interventions: Proprietary Nutritional Supplement, Placebo Supplement; Dietary Supplement
Lead sponsor: Shaklee Corporation; Industry
Eligibility: 45 Years to 65 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Autism Spectrum Disorder
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Emory University; Other
Eligibility: 5 Years to 12 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Multiple Sclerosis
Interventions: Progressive exercise, Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV, Modified paleolithic diet, Omega 3 fatty acids, Full Spectrum vitamin, Essential - hydroxytyrosol, Maltodextrin fiber supplement, Mineral boost (magnesium), Niacinamide, Methyl B12, Taurine, creatine, thiamine, riboflavin, N acetylcysteine, alpha lipoic acid, L acetyl carnitine, methyl folate, coenzyme Q, meditation, self massage, learning, Coconut oil; Other · Device · Dietary Supplement + 1 more
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Rapid Eye Movement Sleep Behavior Disorder, Parkinson Disease
Interventions: Immediate Release Melatonin, Extended Release Melatonin; Dietary Supplement
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Shwachman-Diamond Syndrome
Interventions: Oral Glucose Tolerance Test, Modified Oral Glucose Tolerance Test, Modified Mixed Meal Tolerance Test, Continuous Glucose Monitor, Food Diary, Medical History Questionnaires; Diagnostic Test · Other · Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 3 Years and older
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Autism
Interventions: Synbiotic, Prebiotic; Dietary Supplement
Lead sponsor: University of California, Davis; Other
Eligibility: 2 Years to 11 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Amyotrophic Lateral Sclerosis ALS
Interventions: Astaxanthin, Protandim, Melatonin, MitoQ; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Durham, North Carolina • Philadelphia, Pennsylvania

Conditions: Post Traumatic Stress Disorder, Inflammation
Interventions: Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766), Placebo; Biological · Other
Lead sponsor: VA Eastern Colorado Health Care System; Federal
Eligibility: 18 Years to 60 Years
Enrollment: 383 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Diabetes Mellitus, Type 1, Hypoglycemia, Diabetes Mellitus, Diabetes, Autoimmune
Interventions: Cholecalciferol, Omega 3 fatty acid; Drug
Lead sponsor: Rodolfo Alejandro; Other
Eligibility: 6 Years to 65 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Platinum Resistant Ovarian Cancer, Fallopian Tube Cancers, Peritoneal Carcinoma
Interventions: (Arginaid®) Oral Arginine, (R-Gene® 10) IV Arginine, Pembrolizumab, Bevacizumab, Paclitaxel, oral phosphamide; Drug
Lead sponsor: Rebecca Arend; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Birmingham, Alabama

Search by objective public record fields.

Melatonin and Sleep in Preventing Delirium in the Hospital

Comprehensive Multi-omics Characterization and Implications of Non-Pharmaceutical Dental Hygiene Product in a Randomized Controlled Large Population Study.

Study of Genistein in Reducing Side Effects of Superficial Bladder Cancer Treatment

Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne

A Study of Sabroxy™ (Oroxylum Indicum Extract) for Improving Cognitive Function in Adults With Mild Memory Concerns

The Gut-brain Axis: a Novel Target for Treating Behavioral Alterations in Obesity

Investigational Test of a New Sleep Supplement

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation

The Immediate and Long-term Effects of a Novel Marine-based Iron Supplement in Adult Females

Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?

Ketone Esters for Appetite, Cognition, and Cardiovascular Function in Individuals With Obesity and Insulin Resistance

NEM® Versus Placebo in Exercised-induced Joint Pain, Stiffness, & Cartilage Turnover in Healthy Men & Women

Nicotinamide Adenine Dinucleotide Responses to a Nutritional Supplement

A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder

Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder

Diabetes/ Endocrine Surveillance in SDS

Effect of Milk Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Children With Autism

ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments

Probiotic (LGG) for Veterans With PTSD

Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients

Study of Supplemental Arginine With Chemotherapy and Immunotherapy in Platinum Resistant Ovarian, Fallopian Tube, and Peritoneal Cancer