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Conditions: PGM3
Interventions: N-Acetylglucosamine (GlcNAc), Uridine; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 2 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Vitamin D Deficiency
Interventions: Oral Vitamin D3, Ultraviolet Light; Dietary Supplement · Radiation
Lead sponsor: Rockefeller University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetes Mellitus, Type 1, Hypoglycemia, Diabetes Mellitus, Diabetes, Autoimmune
Interventions: Cholecalciferol, Omega 3 fatty acid; Drug
Lead sponsor: Rodolfo Alejandro; Other
Eligibility: 6 Years to 65 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Type 2 Diabetes
Interventions: vitamin D3, cholecalciferol, Inactive comparator; Dietary Supplement
Lead sponsor: Augusta University; Other
Eligibility: 19 Years to 60 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Hypovitaminosis D, Hypovitaminosis
Interventions: Vitamin Arm 1, Vitamin Arm 2, Vitamin Arm 3, Placebo; Dietary Supplement · Other
Lead sponsor: Madigan Army Medical Center; Federal
Eligibility: 18 Years to 69 Years
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Primary Dysmenorrhea
Interventions: Pau d' Arco; Dietary Supplement
Lead sponsor: National University of Natural Medicine; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Iron Deficiency, Iron Deficiency Anemia (IDA), Vitamin D Deficiency, Vitamin D Insufficiency, Low Energy Availability, Bone Density
Interventions: Iron and Vitamin D Deficiencies Correction; Dietary Supplement
Lead sponsor: Morehouse School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Vitamin D Deficiency, Cystic Fibrosis
Interventions: High-Dose Vitamin D3, Stool Sample, Sputum Sample, Sham Comparator, Blood draw; Dietary Supplement · Other · Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Osteoporosis, Prostate Cancer
Interventions: Calcium, Zoledronic acid, radiation therapy, LHRH, Vitamin D; Dietary Supplement · Radiation · Drug
Lead sponsor: Radiation Therapy Oncology Group; Network
Eligibility: 18 Years and older · Male only
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2014
U.S. locations: 80
States / cities: Chico, California • Los Angeles, California • Pomona, California + 66 more

Conditions: Male Osteoporosis
Interventions: Teriparatide or human parathyroid hormone (PTH) 1-34, Cinacalcet, placebo tablet, Calcium citrate tablet, Vitamin D3; Drug · Dietary Supplement
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years to 85 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Heart Failure
Interventions: Cholecalciferol; Dietary Supplement
Lead sponsor: Case Western Reserve University; Other
Eligibility: 50 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Cystic Fibrosis
Interventions: AquADEKs-2, control multivitamin; Drug · Dietary Supplement
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 10 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 15
States / cities: Tucson, Arizona • Aurora, Colorado • Orlando, Florida + 12 more

Conditions: Coronary Artery Disease, Chronic Kidney Disease, Hypovitaminosis D, Secondary Hyperparathyroidism
Interventions: paricalcitol, placebo; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Deficiency of Vitamin D3, COPD
Interventions: Cholecalciferol, multivitamin, Placebo; Dietary Supplement
Lead sponsor: University of Pittsburgh; Other
Eligibility: 50 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Vitamin D Deficiency
Interventions: Vitamin D, Placebo, Vitamin D + L-cysteine, L-cysteine; Drug
Lead sponsor: Louisiana State University Health Sciences Center Shreveport; Other
Eligibility: 18 Years to 65 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Shreveport, Louisiana

Conditions: Colorectal Cancer, Precancerous Condition
Interventions: cholecalciferol, placebo; Dietary Supplement · Other
Lead sponsor: Northwestern University; Other
Eligibility: 50 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Calcium Phosphate Kidney Stones
Interventions: OHCit- standard dose, Potassium Citrate, Placebo, OHCit- low dose; Dietary Supplement · Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 21 Years to 99 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Vitamin D Deficiency
Interventions: Redoxon VI, placebo; Dietary Supplement
Lead sponsor: Oregon State University; Other
Eligibility: 55 Years to 75 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Corvallis, Oregon

Conditions: Breast Cancer
Interventions: Raloxifene followed by combination therapy, Exemestane followed by combination therapy; Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2008
U.S. locations: 1
States / cities: New York, New York

Conditions: Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Carnitine Palmitoyltransferase Deficiency 2, Very Long Chain Acyl Coa Dehydrogenase Deficiency, Trifunctional Protein Deficiency
Interventions: Nutritional Ketone Supplement, Isocaloric Placebo Supplement; Dietary Supplement
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypoalbuminemia, Protein-energy Malnutrition, Inflammation, Oxidative Stress, Chronic Kidney Disease (CKD) Hemodialysis
Interventions: pentoxiphylline, Nepro, anti-inflammatory module (similar to Oxepa), Placebo pill imitating pentoxiphylline, Placebo to imitate Nepro, Placebo to imitate anti-inflammatory module (similar to Oxepa); Drug · Dietary Supplement
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Irvine, California • Torrance, California

Conditions: Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions, Fracture Healing
Interventions: 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG; Other · Dietary Supplement
Lead sponsor: Cornell University; Other
Eligibility: 40 Years to 90 Years · Female only
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain, Hypertension,Essential
Interventions: IV Vitamin Infused Therapy Treatment, Herbal medicine; Dietary Supplement · Drug
Lead sponsor: Faith A. Richardson; Other
Eligibility: 21 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Dover, Delaware

Conditions: Congenital Disorders of Glycosylation
Interventions: D-Galactose; Dietary Supplement
Lead sponsor: Tulane University; Other
Eligibility: Up to 21 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: New Orleans, Louisiana

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Immunologic Effects of Supplemental Monosaccharide and Nucleoside Derivatives in Patients With Inherited Disorders of Glycosylation

The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile

Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients

The Effect of Vitamin D Supplementation on Glucose Metabolism in Non-Diabetic African American Adults

Evaluating Response to Vitamin D3 and K2 Supplementation in Healthcare Personnel

Effects of Pau d' Arco in Primary Dysmenorrhea

Collegiate Athlete Study

Vitamin D and Microbiota in Cystic Fibrosis

Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

Novel Combination Therapy for Osteoporosis in Men

A Trial of Vitamin D Therapy in Patients With Heart Failure

Effects of an Antioxidant-Enriched Multivitamin Supplement on Inflammation and Oxidative Stress in Cystic Fibrosis

Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease

The Pittsburgh Vitamin D Study: Vitamin D Supplementation in Vitamin D-deficient Subjects at Risk of Lung Cancer

Optimization of Blood Levels of 25(OH)-Vitamin D in African Americans

Vitamin D Supplement in Preventing Colon Cancer in African Americans With Colon Polyps

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults

Combined Estrogen Blockade of the Breast With Exemestane and Raloxifene in Postmenopausal Women With a History of Breast Cancer Who Have No Clinical Evidence of Disease

Oral Ketones and Exercise Among Patients With Long-chain Fatty Acid Oxidation Disorders

Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients

Calcium-Rich Food Versus Calcium Carbonate for Bone Health

The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature

Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation