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ClinicalTrials.gov public records Last synced Oct 14, 2026, 5:32 PM EDT

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Showing 241–264 of 303 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Osteoarthritis Intervention Clear all
Terminated Phase 2 Interventional

A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip

NCT06977568
View directory record Official record
Conditions
Osteoarthritis of Hip
Interventions
Zilretta, Triamcinolone Acetonide
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
50 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 14, 2026, 5:32 PM EDT
Withdrawn Not applicable Interventional

Amnion-Based Injections in the Shoulder

NCT03770546
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Adhesive Capsulitis
Interventions
Amnion Injection, Betamethasone injection
Biological · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 26, 2021 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Not applicable Interventional

Regular Swimming, Vascular Function, and Arthritis

NCT01836380
View directory record Official record
Conditions
Osteoarthritis
Interventions
Exercise Training
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
40 Years to 90 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Oct 14, 2026, 5:32 PM EDT
Terminated Phase 1 Interventional

CAM Procedure With BMAC for Shoulder OA

NCT04826224
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Concentrated bone marrow aspirate administration after Comprehensive Arthroscopic Management (CAM) surgical procedure.
Biological
Lead sponsor
Shane A. Shapiro
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Completed No phase listed Observational

Pathogen Screening in OA Orthopaedic Surgical Patients

NCT03394170
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Collection of specimens prior to and during surgery
Other
Lead sponsor
The Stone Research Foundation for Sports Medicine and Arthritis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Oct 14, 2026, 5:32 PM EDT
Active, not recruiting Not applicable Interventional

Bayer OA Knee Pain Pilot

NCT05349682
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
dynamic contrast enhanced MRI, geniculate artery embolization
Diagnostic Test · Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
25 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Active, not recruiting Not applicable Interventional

Pain & Aging: Combined Interventions for Fitness in the Community Study

NCT04099394
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Behavioral Health, Health Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Not applicable Interventional Results available

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

NCT01280903
View directory record Official record
Conditions
Osteoarthritis, Knee, Hypertension
Interventions
STAR Intervention, Attention-Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Phase 2 Interventional

Exploring Massage Benefits for Arthritis of the Knee

NCT00970008
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Massage 30 min 2x/wk x4 wks then 1x/wk x4 wks, Massage 60 min 2x/wk for 4 wks then 1x/wk for 4 wks, Massage 30 min sessions 1x/wk for 8 wks, Massage 60 min session 1x/wk for 8 wks
Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
35 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Derby, Connecticut • Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Not applicable Interventional Results available

Mobility Optimization Through Velocity Exercise

NCT00844558
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Gait Training, Control
Other
Lead sponsor
University of Iowa
Other
Eligibility
60 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Oct 14, 2026, 5:32 PM EDT
Active, not recruiting No phase listed Observational

Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries

NCT02281747
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
20 Years to 100 Years
Enrollment
521,292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Not applicable Interventional Results available

Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)

NCT03884374
View directory record Official record
Conditions
Osteoarthritis of Knee
Interventions
Focused Breathing and Attention Training (BAT), Standard Breathing and Attention Training (BAT), Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 85 Years
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 14, 2026, 5:32 PM EDT
Recruiting Phase 2 Interventional

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

NCT05839535
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
BDJ, tDCS, sham tDCS, exercise
Behavioral · Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Not applicable Interventional

The Effects of Group Cycling (Spinning®) With Knee Osteoarthritis: A Randomized Control Trial

NCT00917618
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Exercise, Control
Other
Lead sponsor
Mercy Hospital, Pittsburgh, PA
Other
Eligibility
45 Years to 75 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Phase 3 Interventional

Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)

NCT00032890
View directory record Official record
Conditions
Osteoarthritis
Interventions
glucosamine, chondroitin sulfate, glucosamine and chondroitin sulfate combined, celecoxib
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
40 Years and older
Enrollment
1,588 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
16
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 14, 2026, 5:32 PM EDT
Not listed Not applicable Interventional

Trial of Unicompartmental Versus Total Knee Arthroplasty

NCT03385759
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Unicompartmental knee arthroplasty, Total knee arthroplasty
Procedure
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 14, 2026, 5:32 PM EDT
Recruiting Not applicable Interventional

Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being

NCT07222696
View directory record Official record
Conditions
Rheumatoid Arthritis (RA
Interventions
Peer Coach, Healthy Horizons
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Recruiting Not applicable Interventional

Low Dose Radiotherapy for Osteoarthritis

NCT07715188
View directory record Official record
Conditions
Osteoarthitis
Interventions
Low Dose Radiation Therapy
Radiation
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Not yet recruiting Not applicable Interventional

A Trial to Assess the Safety and Effectiveness of an Anatomic Total Shoulder System

NCT07812324
View directory record Official record
Conditions
Shoulder Arthroplasty, Total Shoulder Arthroplasty
Interventions
Mirror Anatomic Total Shoulder Prosthesis, Medacta Anatomic Shoulder
Device
Lead sponsor
Medacta USA
Industry
Eligibility
22 Years and older
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
12
States / cities
Gilbert, Arizona • Boca Raton, Florida • Gulf Breeze, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Not listed Phase 1Phase 2 Interventional

A Hip Flexion Feedback System for Exercise Monitoring in Individuals With Osteoarthritis and Obesity

NCT05997862
View directory record Official record
Conditions
Osteoarthritis, Knee, Obesity
Interventions
HFFS
Device
Lead sponsor
University of Southern Mississippi
Other
Eligibility
30 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Aug 18, 2023 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Occupational Therapy-Delivered Cognitive Behavioral Therapy for Symptomatic Knee Osteoarthritis

NCT02498847
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
ENGAGE
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Oct 14, 2026, 5:32 PM EDT
Enrolling by invitation Not applicable Interventional

Examining the Impact of a Digital Health Program and TENS Device for Patients With Chronic Low Back Pain

NCT07011537
View directory record Official record
Conditions
Back Pain Lower Back Chronic, Chronic Pain, Musculoskeletal Pain
Interventions
Digital Musculoskeletal (MSK) Program, Transcutaneous Electrical Nerve Stimulation (TENS), Standard of Care (SOC)
Behavioral · Device · Other
Lead sponsor
Hinge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Eden Prairie, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 14, 2026, 5:32 PM EDT
Not listed Phase 3 Interventional

Blocking Extracellular Galectin-3 in Patients With Osteoarthritis

NCT02800629
View directory record Official record
Conditions
Osteoarthritis
Interventions
Modified Citrus Pectin, Placebo
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2018 · Synced Oct 14, 2026, 5:32 PM EDT
Completed Phase 4 Interventional

Amniotic Membrane as an Adjunct Treatment for Hallux Rigidus

NCT01825356
View directory record Official record
Conditions
Hallux Rigidus
Interventions
Dorsal Cheilectomy without Amniotic Membrane Tissue Implantation, Dorsal Cheilectomy with Amniotic Membrane Tissue Implantation
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 14, 2026, 5:32 PM EDT