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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:57 PM EDT

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Showing 145–168 of 316 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PAP Clear all
Completed Not applicable Interventional

Motivational Enhancement - Acute Decompensated Heart Failure and OSA

NCT04752462
View directory record Official record
Conditions
Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
Interventions
Telemedicine Intensive Motivational Enhancement
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Phase 2 Interventional Results available

Apnea and Insomnia Relief Study

NCT04007796
View directory record Official record
Conditions
Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
Interventions
Apnea and Insomnia Relief (AIR), Sleep Education (SE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 23, 2026, 10:57 PM EDT
Recruiting Not applicable Interventional

Assessment of Circuit Rebreathing During CPAP Therapy

NCT07062770
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Continuous positive airway pressure (CPAP), Mask exhaust port flow
Device · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional

Portable Monitoring for Diagnosis and Management of Sleep Apnea

NCT00642486
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex), Standard polysomnography (PSG)
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Phase 2 Interventional Results available

Sipuleucel-T With or Without Tasquinimod in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

NCT02159950
View directory record Official record
Conditions
Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
Interventions
Laboratory Biomarker Analysis, Sipuleucel-T, Tasquinimod
Other · Biological · Drug
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 23, 2026, 10:57 PM EDT
Recruiting Not applicable Interventional

Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives

NCT07074288
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
MAD, HGNS
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional

Community Awareness Resources and Education - Project 1

NCT01172561
View directory record Official record
Conditions
Cervical Cancer
Interventions
Lay Health Advisor Education Intervention, Usual Care Group
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 23, 2026, 10:57 PM EDT
Not listed Not applicable Interventional

Addressing Sleep Apnea Post-Stroke/TIA

NCT04322162
View directory record Official record
Conditions
Ischemic Stroke, Transient Ischemic Attack (TIA), Obstructive Sleep Apnea
Interventions
ASAP Intervention Quality Improvement Protocol
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
West Haven, Connecticut • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional

Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea

NCT00263770
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
soft palate implant, Positive airway pressure (PAP)
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 20, 2011 · Synced Oct 23, 2026, 10:57 PM EDT
Not yet recruiting Not applicable Interventional

Evaluation of F&P Mask, US, 2026

NCT07847814
View directory record Official record
Conditions
Chronic Respiratory Conditions, Obstructive Sleep Apnea (OSA)
Interventions
F&P Mask
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional

Recruitment Strategies Comparing Different Strategies in Sleep Apnea and Prediabetes

NCT03984058
View directory record Official record
Conditions
Sleep Disorder, Pre Diabetes, Obstructive Sleep Apnea
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Phase 3 Interventional Results available

Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea

NCT05412004
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
18
States / cities
Riverside, California • Brandon, Florida • Ocala, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Oct 23, 2026, 10:57 PM EDT
Recruiting Not applicable Interventional

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

NCT05988385
View directory record Official record
Conditions
Obstructive Sleep Apnea, Cognitive Decline
Interventions
Positive airway pressure, Oral appliance therapy, Positional therapy
Device
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
55 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Tucson, Arizona • New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment

NCT01939938
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Nasal and Oronasal PAP Mask
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional

SmartScope vs Standard Colposcope for the Evaluation of Cervical Dysplasia

NCT02272075
View directory record Official record
Conditions
Cervical Cancer
Interventions
Mobile OCT M3 scope
Device
Lead sponsor
Scripps Health
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 23, 2026, 10:57 PM EDT
Completed No phase listed Observational

Human Papillomavirus (HPV) and Risk of Cervical Precancer and Cancer

NCT00435214
View directory record Official record
Conditions
Cervical Neoplasia
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
21 Years to 100 Years · Female only
Enrollment
131,110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Oct 23, 2026, 10:57 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers Results available

A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa

NCT03019406
View directory record Official record
Conditions
Glycogen Storage Disease Type II-Pompe's Disease
Interventions
Avalglucosidase alfa (GZ402666), Alglucosidase alfa (GZ419829)
Drug
Lead sponsor
Genzyme, a Sanofi Company
Industry
Eligibility
6 Months to 17 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
3
States / cities
Valhalla, New York • Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Phase 3 Interventional Results available

Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS)

NCT01131312
View directory record Official record
Conditions
Cervical Intraepithelial Neoplasia
Interventions
Thinprep, Hybrid capture 2, Colposcopy
Device · Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 100 Years · Female only
Enrollment
5,060 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Oklahoma City, Oklahoma • Pittsburgh, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Early Phase 1 Interventional

Use of High-Resolution Microendoscopy (HRME) in Patients With Cervical Dysplasia

NCT02420665
View directory record Official record
Conditions
Cervical Cancer
Interventions
Proflavine, HRME Imaging, Phone Call, Colposcopy, Acetic Acid
Drug · Device · Behavioral + 1 more
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Not applicable Interventional Results available

CPAP vs ASV for Insomnia

NCT02365064
View directory record Official record
Conditions
Insomnia, Sleep-Disordered Breathing
Interventions
AirCurve 10 ASV
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Oct 23, 2026, 10:57 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

The Study of Folate Receptor-Mediated Staining Solution (FRD™) In Cervical Lesion Detection

NCT03366493
View directory record Official record
Conditions
Cervical Intraepithelial Neoplasia Grade 2/3
Interventions
FRD, Cytology, HPV testing, Colposcopy, ECC, Biospy
Combination Product · Other · Procedure
Lead sponsor
GY Highland Biotech LLC
Industry
Eligibility
20 Years to 60 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Oct 23, 2026, 10:57 PM EDT
Not listed No phase listed Observational

Non-invasive Pulmonary Artery Prediction

NCT05622695
View directory record Official record
Conditions
Heart Failure, Pulmonary Arterial Hypertension
Interventions
catheterization
Device
Lead sponsor
Silverleaf Medical Sciences INC
Industry
Eligibility
20 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 23, 2026, 10:57 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Study of Intravenous ZMA001 in Healthy Subjects

NCT05967299
View directory record Official record
Conditions
Pulmonary Arterial Hypertension PAH
Interventions
Placebo Cohort 1 (1.5 mg/kg/dose) only, ZMA001 (BC-NKA-20008)
Other · Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 23, 2026, 10:57 PM EDT
Completed Phase 2 Interventional Results available

Two-Arm Study of a DNA Vaccine Encoding Prostatic Acid Phosphatase (PAP) in Patients With Non-Metastatic Castrate-Resistant Prostate Cancer

NCT00849121
View directory record Official record
Conditions
Prostate Cancer
Interventions
pTVG-HP with rhGM-CSF
Biological
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Oct 23, 2026, 10:57 PM EDT