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ClinicalTrials.gov public records Last synced Nov 4, 2026, 4:37 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: PRISM Arm Clear all

Conditions: Depressive Disorder, Major
Interventions: Prism Training; Device
Lead sponsor: GrayMatters Health Ltd.; Industry
Eligibility: 22 Years to 75 Years
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Providence, Rhode Island • Houston, Texas

Conditions: Congenital Heart Disease
Interventions: Promoting Resilience in Stress Management (PRISM), Usual Care; Behavioral · Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Coronary Artery Disease, Smoking Cessation
Interventions: genotype-guided therapy, Nicotine patch, Smoking cessation counseling; Other · Drug · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Homonymous Hemianopia
Interventions: Multi-Periscopic Prism (MPP) glasses, Fresnel Peripheral Prism (FPP) glasses; Device
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 7 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 8
States / cities: Birmingham, Alabama • Denver, Colorado • Palm Springs, Florida + 3 more

Conditions: Post-Traumatic Stress Disorder in Adolescence
Interventions: Prism; Device
Lead sponsor: GrayMatters Health Ltd.; Industry
Eligibility: 12 Years to 21 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Cancer, Bone Marrow Neoplasms, Anxiety, Depression, Quality of Life, Adherence, Medication, Coping Skills, Adolescent Behavior
Interventions: PRISM (Promoting Resilience in Stress Management); Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 12 Years to 24 Years
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 5
States / cities: Birmingham, Alabama • Los Angeles, California • Boston, Massachusetts + 2 more

Conditions: Medication Adherence
Interventions: PRISM Arm, Enhanced Usual Care Arm; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 65 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Spatial Neglect, Stroke
Interventions: Prism adaptation therapy (PAT) + Electrical stimulation (E-stim), Prism adaptation therapy (PAT) + Sham Stimulator, Gait Training; Device · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Sickle Cell Disease
Interventions: Collaborative Care Model, Promoting Resilience in Stress Management; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 8 Years to 25 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: High-risk Smoldering Multiple Myeloma, Smoldering Multiple Myeloma, Multiple Myeloma
Interventions: Teclistamab, Lenalidomide, Dexamethasone; Drug
Lead sponsor: Irene Ghobrial, MD; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2030
U.S. locations: 3
States / cities: Denver, Colorado • Boston, Massachusetts • Portland, Oregon

Conditions: Homonymous Hemianopia
Interventions: High power (57 prism diopter) peripheral prism glasses, Low power sham peripheral prism glasses; Device
Lead sponsor: Alexandra Bowers; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 12
States / cities: Birmingham, Alabama • Palo Alto, California • Jupiter, Florida + 9 more

Conditions: Parkinson
Interventions: Prism adaptation; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 40 Years to 85 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Contraception
Interventions: Electronic Heath Record Platform to Support Pharmacists in Delivering Contraceptive Services; Other
Lead sponsor: OvaryIt, LLC; Industry
Eligibility: 18 Years to 51 Years · Female only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 5
States / cities: Calabasas, California • El Centro, California • Chicago, Illinois + 2 more

Conditions: Cancer
Interventions: mPRISM; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 12 Years to 25 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Unilateral Spatial Neglect, Stroke
Interventions: Prism adaptation training combined with TENS, PAT only; Device · Other
Lead sponsor: Kettering Health Network; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Centerville, Ohio

Conditions: Phenylketonuria (PKU)
Interventions: BMN165 20mg/day, BMN165 40mg/day, Placebo; Drug
Lead sponsor: BioMarin Pharmaceutical; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 29
States / cities: La Jolla, California • Oakland, California • Aurora, Colorado + 26 more

Conditions: Discrimination, Racial, Communication, Chronic Illness, Bias, Racial
Interventions: Promoting Resilience in Stress Management (PRISM); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Type 1 Diabetes Mellitus
Interventions: Promoting Resilience in Stress Management (PRISM); Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 13 Years to 18 Years
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: Houston, Texas • Seattle, Washington

Conditions: Binocular Vision Disorder, Convergence Insufficiency, Headache, Computer Vision Syndrome
Interventions: Neurolens spectacle lens, Placebo spectacle lens; Device
Lead sponsor: Neurolens Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 10
States / cities: Phoenix, Arizona • Conyers, Georgia • Perry, Georgia + 7 more

Conditions: Breast Cancer
Interventions: Promoting Resilience in Stress Management Intervention; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older · Female only
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Pancreatic Ductal Adenocarcinoma (PDAC), Borderline Resectable Pancreatic Cancer, Pancreatic Neoplasms
Interventions: Gemcitabine Delivered by Transarterial Microperfusion; Combination Product
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Extensive Stage Lung Small Cell Carcinoma, Lung Small Cell Carcinoma, A Subtype, Lung Small Cell Carcinoma, I Subtype, Lung Small Cell Carcinoma, N Subtype, Lung Small Cell Carcinoma, P Subtype
Interventions: Biospecimen Collection, Ceralasertib, Computed Tomography, Durvalumab, Etoposide, Magnetic Resonance Imaging, Monalizumab, Platinum Compound, Positron Emission Tomography, Saruparib, Thoracic Radiation Therapy; Procedure · Drug · Biological + 1 more
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 148
States / cities: Loma Linda, California • Rancho Mirage, California • Sacramento, California + 118 more

Conditions: Binocular Vision Disorder, Convergence Insufficiency, Computer Vision Syndrome
Interventions: Neurolens spectacle lens, Placebo spectacle lens; Device
Lead sponsor: Neurolens Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 9
States / cities: Brea, California • Fort Collins, Colorado • Manchester, Connecticut + 6 more

Conditions: Depression, Anhedonia
Interventions: Active RS-EFP, Sham RS-EFP; Device
Lead sponsor: GrayMatters Health Ltd.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Belmont, Massachusetts

Search by objective public record fields.

Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia

Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease

PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo

Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia

The Prism Conformity Trial for Post-Traumatic Stress Disorder in Adolescents

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

Personalized Routine and Habit Integration to Support Medication Management

Spatial-Motor Stroke-Rehab Study

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Immuno-PRISM (PRecision Intervention Smoldering Myeloma)

Clinical Trial of Peripheral Prism Glasses for Hemianopia

Prism Adaptation Treatment of Parkinson's Disease

Patient Experiences With Contraceptive Care Provided by Community Pharmacists Using the Pharmacist Resource to Implement Services as Modules Platform

Resilience Mobile App for Teens and Young Adults With Cancer

Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect

Phase 3 Study to Evaluate the Efficacy & Safety of Self-Administered Injections of BMN165 by Adults With PKU

PRISM Race and Communication Pilot RCT

PRISM for Adolescents With Type 1 Diabetes

Neurolens Headache Study

Promoting Resilience in Women With Breast Cancer

PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP)

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

Neurolens Convergence Insufficiency Study

PRISM Neurofeedback Training for MDD Anhedonic Patients