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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:05 AM EDT

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Showing 25–48 of 75 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pacemaker therapy Clear all
Recruiting Not applicable Interventional

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

NCT06059638
View directory record Official record
Conditions
Hypertension, Hypertension, Systolic, Hypertension, Essential
Interventions
Medtronic Astra/Azure DR MRI IPG with AVIM therapy Activated, Medtronic Astra/Azure DR MRI IPG with AVIM therapy Deactivated
Device
Lead sponsor
Orchestra BioMed, Inc
Industry
Eligibility
18 Years and older
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
72
States / cities
Scottsdale, Arizona • Glendale, California • Newport Beach, California + 60 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 23, 2026, 2:05 AM EDT
Completed No phase listed Observational

A Comparison of Rate Response Performance in Pacemaker Patients With an Indication of Sinus Node Dysfunction

NCT02027909
View directory record Official record
Conditions
Sinus Node Dysfunction
Interventions
Reprogramming dual chamber pacemaker
Device
Lead sponsor
Arun Rao
Other
Eligibility
60 Years to 95 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 23, 2026, 2:05 AM EDT
Enrolling by invitation Not applicable Interventional

Shoulder Pacemaker for Scapular Dyskinesia

NCT05116722
View directory record Official record
Conditions
Scapular Dyskinesis, Posterior Shoulder Instability
Interventions
Shoulder Pacemaker
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 23, 2026, 2:05 AM EDT
Terminated Not applicable Interventional Results available

Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate

NCT00698139
View directory record Official record
Conditions
Heart Failure
Interventions
Medtronic Pacemaker
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 90 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2018 · Synced Oct 23, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

A Trial Assessing The Association Between Type Of Local Anesthesia Treatment And Postoperative Pain In Patients In Having Undergone Arrhythmia Surgery

NCT01300377
View directory record Official record
Conditions
Post-operative Pain
Interventions
Bupivacaine / Lidocaine, Lidocaine
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 23, 2026, 2:05 AM EDT
Recruiting No phase listed Observational

Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

NCT06641362
View directory record Official record
Conditions
Bradycardia, Heart Failure, Ventricular Dysfunction
Interventions
Ultra High Frequency Electrocardiogram (UHF-ECG)
Device
Lead sponsor
VDI Technologies
Industry
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
7
States / cities
Avondale, Arizona • Mesa, Arizona • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 23, 2026, 2:05 AM EDT
Not listed Phase 4 Interventional

Effect of Ranolazine on Valvular Disease in Patients With Pacemakers

NCT01979965
View directory record Official record
Conditions
Ischemic Mitral Regurgitation
Interventions
Ranolazine (Active drug), Placebo
Drug
Lead sponsor
University Cardiology
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 8, 2013 · Synced Oct 23, 2026, 2:05 AM EDT
Completed Phase 2 Interventional

A Comparison of Two Treatments: Pacemaker and Percutaneous Transluminal Septal Ablation for Hypertrophic Cardiomyopathy

NCT00001894
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
pacemaker implantation, percutaneous transluminal septal ablation (PTSA)
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2006 · Synced Oct 23, 2026, 2:05 AM EDT
Completed No phase listed Observational

Optimizing Cardiac Resynchronization

NCT00205192
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac resynchronization pacing
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 29, 2012 · Synced Oct 23, 2026, 2:05 AM EDT
Not listed No phase listed Observational

The Registry Evaluating Functional Outcomes of Resynchronization Management

NCT00959179
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Elgin, Illinois • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 14, 2009 · Synced Oct 23, 2026, 2:05 AM EDT
Withdrawn Not applicable Interventional

Impact of Cardiac Resynchronization Therapy on Right Ventricular Function in Left Ventricular Assist Device Patients

NCT02169076
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Oct 23, 2026, 2:05 AM EDT
Completed No phase listed Observational

Resynchronization Therapy in Young Patients With and Without CHD

NCT00208806
View directory record Official record
Conditions
Dilated Cardiomyopathy, Pediatric
Interventions
congestive heart failure patients
Other
Lead sponsor
Emory University
Other
Eligibility
1 Day to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Oct 23, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional

Chronic Evaluation of Novel Pacemaker System

NCT06056817
View directory record Official record
Conditions
Ventricular Pacing With Rate Response, Bradycardia
Interventions
Calyan Pacemaker
Device
Lead sponsor
Calyan Technologies
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 23, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Physiologic Accelerated Pacing as a Treatment in Patients With Heart Failure With Preserved Ejection Fraction

NCT04546555
View directory record Official record
Conditions
Heart Failure, Diastolic
Interventions
Dual chamber pacemaker, Accelerated Physiologic Pacing, Nocturnal Pacing
Device · Other
Lead sponsor
Daniel L Lustgarten
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 23, 2026, 2:05 AM EDT
Completed Not applicable Interventional

ECG Belt vs. Echocardiographic Optimization of CRT

NCT03305692
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Optimization of CRT Device
Diagnostic Test
Lead sponsor
Alan J. Bank, MD
Other
Eligibility
18 Years to 110 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 23, 2026, 2:05 AM EDT
Withdrawn Phase 1 Interventional

Pilot Study of Electronic Uterine Contraction Inhibitor

NCT00994058
View directory record Official record
Conditions
Prematurity
Interventions
Electrical Inhibition (EI) Uterine Pacemaker
Device
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2015 · Synced Oct 23, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional Results available

Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing

NCT04798768
View directory record Official record
Conditions
Tachycardia, Ventricular, Arrhythmia, Ventricular
Interventions
mCRM Therapy System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
297 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
18
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Jonesboro, Arkansas + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy

NCT04561778
View directory record Official record
Conditions
Heart Failure，Congestive, Cardiomyopathies, Left Ventricular Dysfunction
Interventions
HOT-CRT, Biventricular Pacing
Device
Lead sponsor
Pugazhendhi Vijayaraman
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 23, 2026, 2:05 AM EDT
Withdrawn Phase 2 Interventional

Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical Emboli

NCT02378623
View directory record Official record
Conditions
Patent Foramen Ovale, Cardiac Implantable Electronic Device
Interventions
Apixaban, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 23, 2026, 2:05 AM EDT
Completed No phase listed Observational

Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

NCT01008670
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Respicardia, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
6
States / cities
Birmingham, Alabama • Baltimore, Maryland • Cincinnati, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2010 · Synced Oct 23, 2026, 2:05 AM EDT
Completed Phase 2Phase 3 Interventional

Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure

NCT00180258
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Cardiac Resynchronization Therapy with & without defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Oct 23, 2026, 2:05 AM EDT
Withdrawn Not applicable Interventional

Patent Foramen Ovale (PFO) Closure at the Time of Endovascular Cardiac Electronic Device Implantation

NCT03232450
View directory record Official record
Conditions
Foramen Ovale, Patent
Interventions
Aspirin, Cardiovascular Implantable Device (CIED), Gore Cardioform Septal Occluder
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 23, 2026, 2:05 AM EDT
Terminated Phase 4 Interventional

HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study

NCT00370526
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Acute hemodynamic assessment using PV Loops (CD Leycom, The Netherlands) during LV lead placement
Procedure
Lead sponsor
Stereotaxis
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
3
States / cities
Gainesville, Georgia • Charleston, South Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2008 · Synced Oct 23, 2026, 2:05 AM EDT
Withdrawn Phase 4 Interventional

Remote Interrogation in Rural Emergency Departments

NCT02421549
View directory record Official record
Conditions
Heart Disease, Cardiovascular Disease, Heart Failure, Arrhythmias, Cardiac
Interventions
Unpaired remote monitoring transmitter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 23, 2026, 2:05 AM EDT