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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pain Processing Education Clear all
Completed Not applicable Interventional Results available

Mindfulness and Mechanisms of Pain Processing in Adults With Migraines

NCT02695498
View directory record Official record
Conditions
Migraine
Interventions
Mindfulness Based Stress Reduction, Migraine/stress Education
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 26, 2023 · Synced Sep 5, 2026, 8:43 AM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 5, 2026, 8:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study

NCT01794988
View directory record Official record
Conditions
Chronic Pain
Interventions
Group Cognitive Behavioral Therapy, Pain Education, Therapeutic Interactive Voice Response, NO TIVR
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 19, 2013 · Synced Sep 5, 2026, 8:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Biopsychosocial Influence on Shoulder Pain

NCT02620579
View directory record Official record
Conditions
Shoulder Pain
Interventions
Propranolol LA (60 mg), Placebo, Shoulder Anatomy Education, Pain Processing Education
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 64 Years
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Sep 5, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional

Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)

NCT07290361
View directory record Official record
Conditions
Low Back Pain, Neck Pain
Interventions
Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT), Delivery of Patient Education Materials (System Intervention - Usual Care), Delivery of Patient Education Materials (System Intervention - STEPPT), Referral Specialist Training (System Intervention - Usual Care), Patient Health Navigator Training (System Intervention - STEPPT), Care Navigation (System Intervention - STEPPT), Care navigation audit and feedback (System Intervention - STEPPT), Primary Care Provider training (Provider Intervention - STEPPT), Nurse/Medical Assistant Training (Provider Intervention - STEPPT), Provider feedback on PT referral and adherence (Provider Intervention - STEPPT), Patient education on spine pain condition (Patient Intervention - Usual Care), Patient education on spine pain condition (Patient Intervention - STEPPT), Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care), Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT), Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT), Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care), Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT), Care Navigation (System Intervention - Usual Care), Monitoring of PT referral and adherence rates (System Intervention - STEPPT), Monitoring of PT referral and adherence rates (System intervention - Usual Care)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
17,587 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 5, 2026, 8:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Direct Current Stimulation on Pain Perception

NCT01860950
View directory record Official record
Conditions
Pain
Interventions
anodal tDCS, cathodal tDCS, sham tDCS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Sep 5, 2026, 8:43 AM EDT
Completed Not applicable Interventional

The Effects of Heart Rate Variability Biofeedback Training on Hematopoietic Cell Transplantation Patients

NCT04275830
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplantation, Bone Marrow Transplant, Heart Rate Variability, Autonomic Nervous System, Stress, Mood, Psychological Distress, Emotion Regulation, Communication Research, Narrative
Interventions
Baseline Surveys, Heart rate variability biofeedback, Heart rate variability waitlist and Digital storytelling Control intervention
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 22, 2022 · Synced Sep 5, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional

EPPIC: Easing Pelvic Pain Interventions Clinical Research Program

NCT05127616
View directory record Official record
Conditions
Urologic Chronic Pelvic Pain Syndrome (UCPPS), Interstitial Cystitis, Bladder Pain Syndrome, Chronic Prostatitis, Chronic Pain, Chronic Pelvic Pain Syndrome, Chronic Overlapping Pain Disorders
Interventions
Minimal Contact-Cognitive Behavior Therapy, Patient Education/Support
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
3
States / cities
Los Angeles, California • Ann Arbor, Michigan • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 5, 2026, 8:43 AM EDT
Recruiting Not applicable Interventional

SMART Embedded Intervention for Military Postsurgical Engagement Readiness

NCT05050409
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
Brief mindfulness, Mindfulness-Oriented Recovery Enhancement (MORE), Standard care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 5, 2026, 8:43 AM EDT
Active, not recruiting No phase listed Observational

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

NCT05480904
View directory record Official record
Conditions
ALL, Adult, CNS Tumor, Solid Tumor
Interventions
Neurocognitive (Thinking) Testing, CNS Vital Signs (Thinking) Testing, Health Questionnaires, Sleep Surveys & Sleep Diary, Echocardiography/EKG, Pulmonary Function, Remote Polysomnography, Physical Function
Other · Diagnostic Test · Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 5, 2026, 8:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Music on Nociceptive Processing

NCT04087564
View directory record Official record
Conditions
Pain, Acute, Pain, Chronic, Anxiety, Anxiety Disorders, Catastrophization, Healthy
Interventions
music intervention
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 5, 2026, 8:43 AM EDT
Recruiting Phase 2 Interventional

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

NCT06728579
View directory record Official record
Conditions
Breast Cancer Survivor
Interventions
Mindfulness Oriented Recovery Enhancement (MORE), Questionnaires, Supportive Psychotherapy (SG)
Behavioral · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
San Diego, California • Tallahassee, Florida • Basking Ridge, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 5, 2026, 8:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Music Therapy on Nociceptive Processing

NCT03692247
View directory record Official record
Conditions
Pain, Chronic Pain
Interventions
Smartphone-based Music Intervention
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 5, 2026, 8:43 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Investigating Motor Cortex Processing for Pain Modulation

NCT01404039
View directory record Official record
Conditions
Motor Activity
Interventions
Motor Learning, Somatosensory Learning, Observational Task, Mental Imagery, transcranial direct current stimulation
Behavioral · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 5, 2026, 8:43 AM EDT