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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pain Self-Management Intervention #1 Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Web-based Support to Manage Arthritis Pain

NCT01463189
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Other Arthritic Conditions (e.g., Psoriatic Arthritis)
Interventions
painACTION: Arthritis
Behavioral
Lead sponsor
Inflexxion, Inc.
Industry
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2012 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Evaluation of a Peer Coach-Led Intervention to Improve Pain Symptoms

NCT02380690
View directory record Official record
Conditions
Chronic Pain
Interventions
Peer Coach Assignment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Phase 1 Interventional Results available

An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment

NCT05051644
View directory record Official record
Conditions
Opioid Use Disorder, Chronic Pain
Interventions
Steps 2 Change (S2C), Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional

Internet-based Pain Self-management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

NCT03322644
View directory record Official record
Conditions
Pancreatitis, Chronic, Pancreatitis, Acute Recurrent
Interventions
Internet-based CBT intervention
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery

NCT04637802
View directory record Official record
Conditions
Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital, Kyphosis, Spondylolisthesis
Interventions
CBT (SurgeryPal), Education
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yoga vs. Physical Therapy vs. Education for Chronic Low Back Pain in Minority Populations

NCT01343927
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Weekly yoga classes, Individual physical therapy treatment, Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
8
States / cities
Boston, Massachusetts • Dorchester, Massachusetts • Roslindale, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Sep 29, 2026, 5:14 AM EDT
Recruiting Not applicable Interventional

The PROACTIVE Study for Black Elders

NCT06512727
View directory record Official record
Conditions
Musculoskeletal Pain, Chronic Pain, Osteoarthritis, Pain, Chronic, Movement Evoked Pain
Interventions
PROACTIVE Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 92 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional

Pilot Study: Relaxation and Guided Imagery in Hispanic Persons Diagnosed With Fibromyalgia

NCT00512590
View directory record Official record
Conditions
Fibromyalgia, Pain, Functional Status, Self-Efficacy, Distress
Interventions
Relaxation and Guided Imagery
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2007 · Synced Sep 29, 2026, 5:14 AM EDT
Not yet recruiting Not applicable Interventional

Prevention of Oral Mucositis in Adults in With Hematologic Malignancy

NCT07809984
View directory record Official record
Conditions
Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Oral Mucositis
Interventions
Aloe Vera Mouthwash, Standard of Care
Dietary Supplement · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Oak Lawn, Illinois • Park Ridge, Illinois • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Recruiting Not applicable Interventional

The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System

NCT06940986
View directory record Official record
Conditions
Chronic Pain, Musculoskeletal Pain, Musculoskeletal Pain Disorder
Interventions
Empowered Relief, Move to Health, Usual Care as determined by primary care provider
Behavioral · Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
5
States / cities
Fairbanks, Alaska • Schofield Barracks, Hawaii • San Antonio, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0

NCT05807594
View directory record Official record
Conditions
Gestational Weight Gain, Overweight and Obesity, Pregnancy, Energy Balance
Interventions
HMZ 2.0 Intervention, Attention Control Intervention
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Phase 3 Interventional

Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease

NCT00393250
View directory record Official record
Conditions
Sickle Cell Disease, Pain Management
Interventions
Hypnosis, Control
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional

Adapting and Testing a Novel Self-Compassion Intervention to Reduce Lung Cancer Stigma

NCT06191939
View directory record Official record
Conditions
Lung Cancer
Interventions
Mindful Self-Compassion for Lung Cancer (MSC-LC), Enhanced standard of care with waitlist
Behavioral · Other
Lead sponsor
Loyola Marymount University
Other
Eligibility
18 Years to 100 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Positive Psychology for Chronic Pain Self-management

NCT04321239
View directory record Official record
Conditions
Chronic Pain
Interventions
Positive STEPS
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resilience Skills Self-Management for Chronic Pain.

NCT03304613
View directory record Official record
Conditions
Chronic Spine Pain, Fibromyalgia
Interventions
Web-based Cognitive Behavioral Therapy (e-CBT) Self-Management, Promoting Resilience through Innovative Self-Management
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
35 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Care Management for the Effective Use of Opioids

NCT01236521
View directory record Official record
Conditions
Low Back Pain, Pain
Interventions
Pharmacological (MED), Behavioral treatment (CBT)
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 29, 2026, 5:14 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders

NCT06143228
View directory record Official record
Conditions
Whiplash Injury of Cervical Spine, Muscle Weakness
Interventions
Not listed
Lead sponsor
D'Youville College
Other
Eligibility
19 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Tallahassee, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 29, 2026, 5:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain

NCT06381921
View directory record Official record
Conditions
Abdominal Pain
Interventions
IBS-PPSM intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)

NCT00386243
View directory record Official record
Conditions
Low Back Pain, Pain, Pain, Intractable
Interventions
Cognitive behavioral therapy, Pain self-management program, Co-Analgesic Therapy, Opioid Analgesics
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Sep 29, 2026, 5:14 AM EDT
Recruiting Phase 3 Interventional

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

NCT05834478
View directory record Official record
Conditions
Withdrawal Symptoms, Opioid Use Disorder, Opioid Use
Interventions
Transcutaneous Cervical Vagal Nerve Stimulation, Sham Stimulation, [F-18]Fallypride
Device · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Not yet recruiting Phase 2 Interventional

NAC-REPAIR for Post-surgical Pain

NCT07227649
View directory record Official record
Conditions
Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal, Dupuytren Contracture, Morton Neuroma, Tarsal Tunnel Syndrome, Plantar Fasciopathy, Peroneal Nerve Entrapment
Interventions
NAC, NAC 0mg/day (Placebo)
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Trial of Self-managed Approaches for Patellofemoral Pain Syndrome in Active Duty

NCT02597673
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Home Exercise Program (HEP), NMES, TENS
Other · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

Communication and Activation in Pain to Enhance Relationships and Treat Pain With Equity

NCT03562793
View directory record Official record
Conditions
Pain
Interventions
Communication and Activation in Pain to Enhance Relationships and Treat Pain with Equity (COOPERATE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 29, 2026, 5:14 AM EDT
Completed Not applicable Interventional

MS Symptom Management Study

NCT02474940
View directory record Official record
Conditions
Multiple Sclerosis, Chronic Pain, Fatigue
Interventions
Intervention #1, Intervention #2, Intervention #3
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 25, 2017 · Synced Sep 29, 2026, 5:14 AM EDT