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ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:35 PM EDT

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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Patching Clear all
Recruiting Not applicable Interventional

Video Treatment for Amblyopia

NCT05439200
View directory record Official record
Conditions
Amblyopia
Interventions
Asynchronous 3D movies, Patching
Device
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
3 Years to 7 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional Results available

Full-Time Occlusion Therapy for Intermittent Exotropia in Children

NCT05462821
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Eye Patch
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 8 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
25
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Berkeley, California + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 3, 2026, 2:35 PM EDT
Completed No phase listed Interventional Results available

A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming

NCT03066063
View directory record Official record
Conditions
Amblyopia, Ocular Motility Disorders
Interventions
iCare, Amblyopia standard of Care, CI standard of Care
Device · Behavioral
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
4 Years to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Augmenting Patching Treatment for Amblyopia With Physical Exercise

NCT03822806
View directory record Official record
Conditions
Amblyopia
Interventions
Physical Exercise in addition to Patching
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
5 Years to 16 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Dichoptic Video Treatment for Amblyopia

NCT03825107
View directory record Official record
Conditions
Amblyopia
Interventions
patching, Dichoptic videos
Other
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
3 Years to 7 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 2 Interventional Results available

Pilot Study to Evaluate Levodopa as Treatment for Residual Amblyopia

NCT00789672
View directory record Official record
Conditions
Amblyopia
Interventions
levodopa/carbidopa, patching
Drug · Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
8 Years to 17 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 3, 2026, 2:35 PM EDT
Not listed Not applicable Interventional

New Pediatric Patching Method to Improve Compliance

NCT02236351
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Pinch Patch/ flat Patch
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 7 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Not applicable Interventional

CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY

NCT04785690
View directory record Official record
Conditions
Amblyopia
Interventions
CureSight, Patching
Device
Lead sponsor
NovaSight
Industry
Eligibility
4 Years to 8 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional

Amblyopia (Lazy Eye) Treatment Study

NCT00001864
View directory record Official record
Conditions
Amblyopia, Anisometropia, Strabismus
Interventions
Atropine, Patch
Drug · Device
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

"Eye Protection After Mydriatic Use for ROP Screening: Impact on Vitals Signs and Pain Scores"

NCT01860534
View directory record Official record
Conditions
Light Sensitivity
Interventions
eye covers
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 3, 2026, 2:35 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia

NCT02687581
View directory record Official record
Conditions
Amblyopia
Interventions
IO-therapy Glasses, patch
Device
Lead sponsor
Salus University
Other
Eligibility
3 Years to 8 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Sep 3, 2026, 2:35 PM EDT
Terminated Not applicable Interventional Results available

Comparison of AmblyzTM Glasses and Patching for Amblyopia

NCT01973348
View directory record Official record
Conditions
Amblyopia
Interventions
4-hour AmblyZ glasses, 12-hour AmblyZ glasses, 2-hour patching, 6-hour patching
Device
Lead sponsor
Indiana University
Other
Eligibility
3 Years to 8 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Treatment of Residual Amblyopia With Donepezil

NCT01584076
View directory record Official record
Conditions
Amblyopia
Interventions
Donepezil, Patching
Drug · Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
3
States / cities
Boston, Massachusetts • Waltham, Massachusetts • Weymouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 3, 2026, 2:35 PM EDT
Recruiting Phase 3 Interventional

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

NCT04378790
View directory record Official record
Conditions
Amblyopia
Interventions
Patching, Glasses
Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
68
States / cities
Birmingham, Alabama • Glendale, Arizona • Phoenix, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional Results available

Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children

NCT00525174
View directory record Official record
Conditions
Amblyopia
Interventions
Bangerter filters, Patching, Near activities
Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 9 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional

Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children

NCT00091923
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch, Spectacles
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional

An Evaluation of Treatment of Amblyopia in Children 7 To <18 Years Old

NCT00094692
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch, spectacles, atropine
Device · Drug
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
7 Years to 17 Years
Enrollment
507 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
3
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional Results available

Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds

NCT00315328
View directory record Official record
Conditions
Amblyopia
Interventions
Atropine, Patching, Near activities
Drug · Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
7 Years to 12 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2016 · Synced Sep 3, 2026, 2:35 PM EDT
Active, not recruiting Not applicable Interventional

Binocular iPad Sub-Study

NCT02365090
View directory record Official record
Conditions
Amblyopia
Interventions
patching, binocular games
Other
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
4 Years to 14 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Phase 3 Interventional

Trial Comparing Near Versus Distance Activities While Patching for Amblyopia in Children 3 to <7 Years Old

NCT00315198
View directory record Official record
Conditions
Amblyopia
Interventions
Eye Patch, Near activities, Distance activities
Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 6 Years
Enrollment
425 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
2
States / cities
Bloomington, Indiana • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Sep 3, 2026, 2:35 PM EDT
Not listed Phase 4 Interventional

Post Intravitreal Injection Topical NSAID vs. Patching

NCT03918590
View directory record Official record
Conditions
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
Interventions
nepafenac 0.3% suspension (Ilevro; Alcon, Fort Worth, TX), Theratears tear drop, (Akron, Ann 111 Arbor, MI), patching
Drug · Other
Lead sponsor
The New York Eye & Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 3, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

Study of Binocular Computer Activities for Treatment of Amblyopia

NCT02200211
View directory record Official record
Conditions
Amblyopia
Interventions
iPad®, Patching 2 hours per day, 7 days per week
Device · Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
5 Years to 16 Years
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Rochester, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Sep 3, 2026, 2:35 PM EDT