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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:19 AM EDT

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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Patching Clear all
Terminated Phase 1 Interventional

Proof of Concept Study of Binocular Videogames Versus Patching for Amblyopia

NCT04784390
View directory record Official record
Conditions
Amblyopia
Interventions
Binocular video games, Patching of the sound eye
Device
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
4 Years to 12 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Gainesville, Florida • Maitland, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional

Trial Comparing Near Versus Distance Activities While Patching for Amblyopia in Children 3 to <7 Years Old

NCT00315198
View directory record Official record
Conditions
Amblyopia
Interventions
Eye Patch, Near activities, Distance activities
Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 6 Years
Enrollment
425 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
2
States / cities
Bloomington, Indiana • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Oct 20, 2026, 11:19 AM EDT
Terminated Phase 3 Interventional Results available

Combined Patching-Atropine for Residual Amblyopia

NCT00506675
View directory record Official record
Conditions
Amblyopia
Interventions
Patching, Atropine
Device · Drug
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 9 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional Results available

Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children

NCT00525174
View directory record Official record
Conditions
Amblyopia
Interventions
Bangerter filters, Patching, Near activities
Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 9 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional

Amblyopia (Lazy Eye) Treatment Study

NCT00001864
View directory record Official record
Conditions
Amblyopia, Anisometropia, Strabismus
Interventions
Atropine, Patch
Drug · Device
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional

Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia

NCT00094744
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2010 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

"Eye Protection After Mydriatic Use for ROP Screening: Impact on Vitals Signs and Pain Scores"

NCT01860534
View directory record Official record
Conditions
Light Sensitivity
Interventions
eye covers
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 20, 2026, 11:19 AM EDT
Recruiting Phase 3 Interventional

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

NCT06380517
View directory record Official record
Conditions
Amblyopia
Interventions
Luminopia, Eye Patch
Device · Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
4 Years to 7 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
72
States / cities
Birmingham, Alabama • Glendale, Arizona • Scottsdale, Arizona + 58 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 20, 2026, 11:19 AM EDT
Terminated Not applicable Interventional Results available

Comparison of AmblyzTM Glasses and Patching for Amblyopia

NCT01973348
View directory record Official record
Conditions
Amblyopia
Interventions
4-hour AmblyZ glasses, 12-hour AmblyZ glasses, 2-hour patching, 6-hour patching
Device
Lead sponsor
Indiana University
Other
Eligibility
3 Years to 8 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 25, 2017 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Treatment of Residual Amblyopia With Donepezil

NCT01584076
View directory record Official record
Conditions
Amblyopia
Interventions
Donepezil, Patching
Drug · Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
3
States / cities
Boston, Massachusetts • Waltham, Massachusetts • Weymouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional

Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children

NCT00091923
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch, Spectacles
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Not applicable Interventional

Augmenting Patching Treatment for Amblyopia With Physical Exercise

NCT03822806
View directory record Official record
Conditions
Amblyopia
Interventions
Physical Exercise in addition to Patching
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
5 Years to 16 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Oct 20, 2026, 11:19 AM EDT
Recruiting No phase listed Observational

Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy

NCT04310241
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Patching therapy, Glasses
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
6 Months to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional

Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

NCT00000170
View directory record Official record
Conditions
Amblyopia
Interventions
Atropine, Eye Patch
Drug · Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
Up to 6 Years
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 6, 2014 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 3 Interventional Results available

Increasing Patching for Amblyopia in Children 3 to < 8 Years Old

NCT00945100
View directory record Official record
Conditions
Amblyopia
Interventions
Eye Patch
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Asthma and Pest Control Study: Demonstrating Return-on-Investment for In-Home Pest Control for Children With Persistent Asthma

NCT02700542
View directory record Official record
Conditions
Asthma
Interventions
Integrated Pest Management
Other
Lead sponsor
New York City Department of Health and Mental Hygiene
Government
Eligibility
5 Years to 12 Years
Enrollment
384 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Not applicable Interventional

Dichoptic Video Treatment for Amblyopia

NCT03825107
View directory record Official record
Conditions
Amblyopia
Interventions
patching, Dichoptic videos
Other
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
3 Years to 7 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 20, 2026, 11:19 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Docosahexaenoic Acid (DHA) Supplementation in Amblyopia

NCT03402789
View directory record Official record
Conditions
Amblyopia
Interventions
Docosahexaenoic Acid, Placebo Oral Tablet
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
3 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 20, 2026, 11:19 AM EDT
Terminated Not applicable Interventional Results available

Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia

NCT02687581
View directory record Official record
Conditions
Amblyopia
Interventions
IO-therapy Glasses, patch
Device
Lead sponsor
Salus University
Other
Eligibility
3 Years to 8 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2022 · Synced Oct 20, 2026, 11:19 AM EDT
Completed Phase 2 Interventional Results available

Pilot Study to Evaluate Levodopa as Treatment for Residual Amblyopia

NCT00789672
View directory record Official record
Conditions
Amblyopia
Interventions
levodopa/carbidopa, patching
Drug · Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
8 Years to 17 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 20, 2026, 11:19 AM EDT
Recruiting Not applicable Interventional

Patch-free Occlusion Therapy

NCT05440448
View directory record Official record
Conditions
Amblyopia
Interventions
Patch-free occlusion therapy, Adhesive patch
Device
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
3 Years to 12 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 20, 2026, 11:19 AM EDT
Terminated Phase 3 Interventional Results available

Trial Comparing Patching With Active Vision Therapy to Patching With Control Vision Therapy as Treatment for Amblyopia

NCT00587171
View directory record Official record
Conditions
Amblyopia
Interventions
Patching, Near activities, Active vision therapy, Control vision therapy
Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
7 Years to 12 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
7
States / cities
Birmingham, Alabama • Miami, Florida • Bloomington, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 20, 2026, 11:19 AM EDT
Not listed Not applicable Interventional

New Pediatric Patching Method to Improve Compliance

NCT02236351
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Pinch Patch/ flat Patch
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 7 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 20, 2026, 11:19 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Caffeine in Amblyopia Study

NCT02594358
View directory record Official record
Conditions
Amblyopia
Interventions
Caffeine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
7 Years to 13 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Oct 20, 2026, 11:19 AM EDT