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ClinicalTrials.gov public records Last synced Oct 28, 2026, 9:43 AM EDT

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Showing 241–264 of 1,268 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pathway Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Reactive Oxygen Species in the Pathogenesis of Diabetic Complications

NCT00703989
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
benfotiamine, α-lipoic acid
Dietary Supplement
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 28, 2026, 9:43 AM EDT
Active, not recruiting Not applicable Interventional

Communication Bridge Pilot Study

NCT06211374
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Communication Bridge
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Not applicable Interventional Results available

NuVent™ Revision Study

NCT02284347
View directory record Official record
Conditions
Chronic Rhinosinusitis
Interventions
Electromagnetic Sinus Dilation System (NuVent™)
Device
Lead sponsor
Medtronic Surgical Technologies
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Phase 1 Interventional

GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment

NCT00822458
View directory record Official record
Conditions
Recurrent Childhood Medulloblastoma
Interventions
vismodegib, laboratory biomarker analysis, pharmacological study
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
3 Years to 21 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
9
States / cities
San Francisco, California • Washington D.C., District of Columbia • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2014 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Phase 1 Interventional Results available

Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042

NCT03307785
View directory record Official record
Conditions
Neoplasms, Metastatic Cancer, Advanced Cancer, Solid Tumor, Non Small Cell Lung Cancer Metastatic, Non Small Cell Lung Cancer Stage IIIB, Non Small Cell Lung Cancer
Interventions
Niraparib, TSR-042, Carboplatin-Paclitaxel, Bevacizumab, TSR-022, Carboplatin-Pemetrexed, Carboplatin-Nab-Paclitaxel
Drug
Lead sponsor
Tesaro, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
8
States / cities
Scottsdale, Arizona • Encinitas, California • San Marcos, California + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 28, 2026, 9:43 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC

NCT05682443
View directory record Official record
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
ONC-392 low, ONC-392 high, lutetium Lu 177 vipivotide tetraxetan
Drug
Lead sponsor
OncoC4, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
23
States / cities
Sacramento, California • Aurora, Colorado • Tampa, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Not applicable Interventional

Impact of a Lower Extremity Amputation Pathway Protocol in Dysvascular Patients

NCT03592316
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Lower Extremity Amputation Pathway
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 28, 2026, 9:43 AM EDT
Completed No phase listed Observational

PET Imaging of the Immune System Using Analog Probes

NCT03409419
View directory record Official record
Conditions
Malignant Melanoma
Interventions
[18F] CFA
Drug
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 28, 2026, 9:43 AM EDT
Not yet recruiting Not applicable Interventional

The PIONEER Comparative Effectiveness Study - Project 2

NCT07829107
View directory record Official record
Conditions
Head Injury Trauma, Traumatic Brain Injury, Mild
Interventions
Clinical pathway 1: Guidelines plus biomarkers, Clinical guidelines only
Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Sylmar, California • Torrance, California • Clinton Township, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 28, 2026, 9:43 AM EDT
Completed No phase listed Observational

High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification

NCT02984436
View directory record Official record
Conditions
Acute Coronary Syndrome, Chest Pain
Interventions
Blood Sample, HEART Score
Procedure · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
1,572 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
6
States / cities
Sacramento, California • Gainesville, Florida • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 28, 2026, 9:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fathers' Support Center New Pathways to Responsible Fatherhood Family Formation Program (NPFF) Impact Evaluation Plan

NCT03413709
View directory record Official record
Conditions
Parenting
Interventions
Family Formation Program
Other
Lead sponsor
Fathers' Support Center, St. Louis
Other
Eligibility
16 Years and older · Male only
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 28, 2026, 9:43 AM EDT
Not yet recruiting Not applicable Interventional

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

NCT07145099
View directory record Official record
Conditions
Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions
PT Group, Usual Care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 28, 2026, 9:43 AM EDT
Terminated Phase 1 Interventional

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

NCT00112619
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Leukemia, Lymphoma, Unspecified Childhood Solid Tumor, Protocol Specific
Interventions
topotecan hydrochloride
Drug
Lead sponsor
Pediatric Brain Tumor Consortium
Network
Eligibility
3 Years to 21 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
11
States / cities
San Francisco, California • Washington D.C., District of Columbia • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2011 · Synced Oct 28, 2026, 9:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke

NCT05801744
View directory record Official record
Conditions
Stroke, Post-stroke Hemiparesis, Foot Drop
Interventions
Operant conditioning
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 28, 2026, 9:43 AM EDT
Not listed No phase listed Observational

Assessment of Visual Function With a Portable Brain-computer Interface

NCT03760055
View directory record Official record
Conditions
Glaucoma, Age Related Macular Degeneration, Optic Neuropathy, Retinal Degeneration
Interventions
nGoggle
Device
Lead sponsor
NGoggle
Industry
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Timeline
2019 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Oct 28, 2026, 9:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Circadian Timing, Information Processing and Energy Balance Study

NCT04759755
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 28, 2026, 9:43 AM EDT
No Longer Available No phase listed Expanded access

Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors

NCT04681248
View directory record Official record
Conditions
Esophageal Neoplasm, Adenocarcinoma of the Gastroesophageal Junction, GastroEsophageal Cancer, Squamous Cell Carcinoma, Gastric Adenocarcinoma, Endometrial Cancer, Uterine Cancer, Ovarian Cancer, Carcinosarcoma, Gastric Cancer
Interventions
DKN-01
Drug
Lead sponsor
Leap Therapeutics, Inc.
Industry
Eligibility
18 Years and older
U.S. locations
5
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 28, 2026, 9:43 AM EDT
Recruiting Not applicable Interventional

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

NCT06094478
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke, Acute, Hemorrhagic Stroke
Interventions
HI-SPEED Protocol
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
8
States / cities
New Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 28, 2026, 9:43 AM EDT
Not listed Not applicable Interventional

Impact of Integrated Care Pathways for Prevention of Post-operative Urinary Retention (POUR)

NCT03863743
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Urinary Retention
Interventions
integrated care pathway, physician's standard of care
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Phase 4 Interventional

Ziconotide as First-Line IDT

NCT03321955
View directory record Official record
Conditions
Neuropathic Pain
Interventions
Ziconotide 100 MCG(microgram)/ML Intrathecal Solution, Quantitative sensory testing, Serum markers: Interleukin-1, Interleukin-6, and tumor necrosis factor
Drug · Diagnostic Test
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 28, 2026, 9:43 AM EDT
Recruiting Phase 2 Interventional

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

NCT06541249
View directory record Official record
Conditions
Polycythemia Vera (PV), Essential Thrombocythemia (ET), Myelofibrosis (MF)
Interventions
Methotrexate (MTX)
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 28, 2026, 9:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent-Child EF Intervention

NCT06924307
View directory record Official record
Conditions
Cognitive Intervention to Promote Healthy Development of Executive Function (EF) Skills in Young Children
Interventions
Executive Function Intervention
Device
Lead sponsor
Koronis Biomedical Technologies
Industry
Eligibility
2 Years to 5 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Minneapolis, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Not applicable Interventional

SUSTAIN: Behavior Change and Nutrition Security for CKMS

NCT06589336
View directory record Official record
Conditions
Stage 2 Cardiovascular-Kidney-Metabolic Syndrome, Cardiovascular Disease Other
Interventions
Dietary changes via Instacart vouchers, Dietary changes via access to Mid-Ohio Farmacy, Behavior changes via access to Health Impact Ohio Hub, Behavioral nutrition counseling, Cooking classes, Dietary changes to Delivery fees
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 28, 2026, 9:43 AM EDT
Completed Phase 4 Interventional

Perioperative Steroid Dosing on the APR in AIS

NCT05561725
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
Dexamethasone postoperative, Standard of Care
Drug
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 28, 2026, 9:43 AM EDT