Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 12:09 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Patient letters Clear all

Conditions: Atrial Fibrillation, Stroke
Interventions: Early Patient-Level and Provider-Level Educational Intervention, Delayed Provider-Level Educational Intervention; Behavioral
Lead sponsor: Harvard Pilgrim Health Care; Other
Eligibility: 30 Years and older
Enrollment: 64,666 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 4
States / cities: Louisville, Kentucky • Quincy, Massachusetts • Waltham, Massachusetts + 1 more

Conditions: Colorectal Cancer
Interventions: Branch I, Branch II, Branch III, Branch IV, Branch V; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 50 Years to 74 Years
Enrollment: 7,711 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Fort Worth, Texas

Conditions: Diabetic Retinal Disease
Interventions: Visual Acuity, Reading Speed, Visual Field testing, Contrast sensitivity, Electroretinography (ERG) and pupillography in light- and dark-adapted states, Ultrawide field-color photograph, Ultrawide field-Fluorescein angiogram, Optical coherence tomography, Optical coherence tomography- Angiography; Diagnostic Test · Other
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 8
States / cities: Huntington Beach, California • Augusta, Georgia • Boston, Massachusetts + 5 more

Conditions: Post-traumatic Stress Disorder, Moral Injury, Traumatic Loss
Interventions: Adaptive Disclosure for Moral Injury and Loss, Present Centered Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 5
States / cities: San Diego, California • San Francisco, California • Boston, Massachusetts + 2 more

Conditions: Concordance Between Colonoscopy Follow up Interval Noted in Patient Letters vs. Electronic Health Record Chart, Colorectal Cancer
Interventions: Assistance with implementing Epic Smartlist; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: Not listed
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alzheimer Disease
Interventions: Collaborative Dementia Care Program, Screening Only; Behavioral · Other
Lead sponsor: Indiana University; Other
Eligibility: 65 Years and older
Enrollment: 1,822 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Indianapolis, Indiana

Conditions: Epilepsy
Interventions: Luminosity Trial Memory Match, Luminosity Trial Memory Matrix, Luminosity Trial Famliar Faces, Luminosity Trial Brain Shift, Luminosity Trial Star Search, Luminosity Trial Word Bubbles, Luminosity Trial Color Match, Luminosity Trial Ebb and Flow, Luminosity TrialChalk Board Challenge, Luminosiuty Follow that Frog, Luminosity Train of Thought; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 55 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions: Stepped Care Management; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 14 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Substance-Related Disorders
Interventions: Standard letter, Comparator letter; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 541 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Suicide, Suicide, Attempted, Suicidal Ideation
Interventions: DBT Online Program; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cancer
Interventions: Baseline Participant Assessment, Baseline Healthcare Provider Assessment, Follow-up Participant Assessment, Follow-up Healthcare Provider Assessment, End-of-study Participant Assessment, End-of-study Healthcare Provider Assessment; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 65 Years and older
Enrollment: 227 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Opioid-use Disorder, Opioid Misuse, Opioid Use, Chronic Pain
Interventions: Care Continuity Program; Other
Lead sponsor: Sure Med Compliance; Industry
Eligibility: 18 Years and older
Enrollment: 1,840 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Mobile, Alabama

Conditions: Diabetes Mellitus
Interventions: Tailored letter; Other
Lead sponsor: Scranton-Temple Residency Program; Other
Eligibility: 18 Years to 75 Years
Enrollment: 467 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Scranton, Pennsylvania

Conditions: Malignant Glioma
Interventions: Psychological Intervention; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gastroesophageal Reflux Disease, Diabetic Gastroparesis
Interventions: intervention letter; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: Not listed
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Diabetes Mellitus, Cardiovascular Disease
Interventions: Interactive Voice Recognition (IVR) phone calls, Educational mailings and follow-up for nonadherence; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 40 Years and older
Enrollment: 21,752 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 3
States / cities: Atlanta, Georgia • Honolulu, Hawaii • Portland, Oregon

Conditions: CKD - Chronic Kidney Disease
Interventions: Letter Intervention, Letter + Phone Call Intervention:, Augmented usual care; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years to 80 Years
Enrollment: 1,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Surgery, Aging
Interventions: Peer Comparison Feedback, Patient Informational Letter; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 65 Years and older
Enrollment: 517,611 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Acute Musculoskeletal Pain, Chronic Pain
Interventions: Educational Video, Telecare, Correspondence with Primary Care Provider; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 50 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Mammography, Medical Overuse, Evidence-based Practice, Older Adults
Interventions: Enhanced Usual Care (EUC), Multilevel De-Implementation Strategy; Other · Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Glaucoma
Interventions: Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart; Diagnostic Test
Lead sponsor: Wills Eye; Other
Eligibility: 18 Years and older
Enrollment: 314 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Vaccination
Interventions: Standard PCP Outreach, Culturally Tailored PCP Outreach; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 65 Years and older
Enrollment: 8,287 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Oakland, California

Conditions: Opioid Abuse
Interventions: Overdose Notification; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Overdose
Interventions: MHC Outreach Intervention; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Search by objective public record fields.

IMplementation of an RCT to imProve Treatment With Oral AntiCoagulanTs in Patients With Atrial Fibrillation

The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation

Longitudinal Natural History Study of Retinal Function in Eyes of Patients With Diabetes

Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure

Colonoscopy Screening: Setting Epic Follow-up Times

Caregiver Outcomes of Alzheimer's Disease Screening

Computerized Cognitive Training for Patients With Epilepsy

Trauma Survivors Outcomes and Support Study IV

Encouraging Judicious Prescribing of Opioids in Los Angeles County

Now Matters Now: An Online Suicide Prevention Program

Optimizing Fall-risk Prediction in Older Adults With Cancer

Comparing a Patient Self-Assessment Software to Treatment as Usual in Opioid Prescriber and Patient Opioid Outcomes

Can Tailored Patient Letters Improve The Quality Of Diabetic Patient Care?

Psychological Intervention for Caregivers of Patients With Malignant Gliomas

Improving Metoclopramide Prescribing Practices at Penn Through a Physician-targeted Intervention

Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies

The Use of Risk Prediction to Identify Patients at Risk for Chronic Kidney Disease: Patient and Provider Interventions for Patients at High Risk for Chronic Kidney Disease

De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients

Reducing the Transition From Acute to Chronic Musculoskeletal Pain Among Older Adults

A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women

Spaeth/Richman Contrast Sensitivity Test

Effect of Electronic and Mail Outreach From Primary Care Physicians for COVID-19 Vaccination Among Elderly Patients

AESOPS Trial 2 (AESOPS-2): Availability of Opioid Harm

Evaluation of a Medication Health Center to Promote Opioid Safety