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ClinicalTrials.gov public records Last synced Oct 5, 2026, 2:24 PM EDT

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Showing 49–72 of 168 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Patients with Atrial Fibrillation (AF) Clear all
Not listed No phase listed Observational

Cognitive Impairment in Atrial Fibrillation

NCT01816308
View directory record Official record
Conditions
Atrial Fibrillation, Mild Cognitive Impairment, Dementia
Interventions
Not listed
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
50 Years to 75 Years
Enrollment
888 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 3 Interventional Results available

First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)

NCT00392054
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
Procedure · Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
19 Years to 75 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational

Is Endothelial Function a Predictor of Successful Ablation Therapy Provided to Patients With Atrial Fibrillation?

NCT02129842
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Itamar-Medical, Israel
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
New York, New York • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational

Study to Develop a Tool to Estimate the Kidney Function in Databases Without Laboratory Data

NCT03605810
View directory record Official record
Conditions
Renal Function
Interventions
No Intervention
Other
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
5,132,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Whippany, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 3 Interventional Results available

Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/Persistent

NCT00506493
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cardioblate Surgical Ablation System, Surgical RF Ablation
Device · Procedure
Lead sponsor
Medtronic Cardiac Surgery
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Phoenix, Arizona • Concord, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 5, 2026, 2:24 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

KardiaMobile ECG Monitoring Effects on Health Care Utilization and Patient Experience With Atrial Fibrillation

NCT05407415
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Kardia Mobile 6L Device
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 3 Interventional Results available

Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation

NCT00781391
View directory record Official record
Conditions
Stroke, Atrial Fibrillation, Embolism
Interventions
warfarin tablets, Edoxaban tablets (high dose regimen-60mg), Edoxaban tablets (low dose regimen-30mg), placebo warfarin, placebo edoxaban
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
21 Years and older
Enrollment
21,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
316
States / cities
Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 308 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Stroke Feasibility Study

NCT01997905
View directory record Official record
Conditions
Atrial Fibrillation, AFib
Interventions
AtriClip LAA Exclusion Device
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
7
States / cities
St. Helena, California • Miami, Florida • Indianapolis, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational

Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients

NCT07580937
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Arrhythmia
Interventions
Data collection
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
10
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 2 Interventional Results available

Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation

NCT03032965
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Adenosine, Isoproterenol
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 2 Interventional Results available

Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery

NCT00903370
View directory record Official record
Conditions
Atrial Fibrillation, Mitral Valve Insufficiency, Mitral Valve Stenosis
Interventions
MVS, Ablation
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
18
States / cities
New Haven, Connecticut • Newark, Delaware • Atlanta, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2017 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 2 Interventional

Combined Treatment of Arterial Hypertension and Atrial Fibrillation

NCT01897545
View directory record Official record
Conditions
Arterial Hypertension, Atrial Fibrillation
Interventions
Circumferential PV isolation, PV isolation+renal denervation
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2013 · Synced Oct 5, 2026, 2:24 PM EDT
Not listed Not applicable Interventional

Natural History of COVID-19-Related Atrial Fibrillation

NCT04830774
View directory record Official record
Conditions
COVID-19, Atrial Fibrillation New Onset
Interventions
ILR, PMK, ICD
Device
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Kansas City, Kansas • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational

Perioperative Anticoagulant Use for Surgery Evaluation Study

NCT02228798
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
3,135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
Aurora, Colorado • Evanston, Illinois • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2019 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)

NCT01165710
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Patients with Atrial Fibrillation (AF)
Other
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
10,179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
168
States / cities
Birmingham, Alabama • Dothan, Alabama • Huntsville, Alabama + 165 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial Fibrillation Patients and Controls

NCT04766814
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmia
Interventions
Not listed
Lead sponsor
Tulane University
Other
Eligibility
20 Years to 80 Years · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 5, 2026, 2:24 PM EDT
Active, not recruiting Phase 4 Interventional

Liraglutide Effect in Atrial Fibrillation

NCT03856632
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Liraglutide, RFM, Anti Arrhythmics, Afib Catheter Ablation
Drug · Other · Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 2 Interventional Results available

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure

NCT01970501
View directory record Official record
Conditions
Current or Recent History of Atrial Fibrillation
Interventions
bucindolol hydrochloride, metoprolol succinate, Placebo oral capsule
Drug · Other
Lead sponsor
ARCA Biopharma, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
48
States / cities
Anchorage, Alaska • Phoenix, Arizona • East Palo Alto, California + 43 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Phase 3 Interventional Results available

Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) Study

NCT00431834
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cardioblate System Surgical Ablation System, Surgical RF Ablation
Device · Procedure
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Phoenix, Arizona • Concord, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational Results available

GLORIA-AF Registry Program - Second and Third Phases

NCT01468701
View directory record Official record
Conditions
Stroke, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
37,235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
324
States / cities
Mobile, Alabama • Northport, Alabama • Scottsboro, Alabama + 265 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 5, 2026, 2:24 PM EDT
Completed No phase listed Observational

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II)

NCT01701817
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Patients with Atrial Fibrillation
Other
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
21 Years and older
Enrollment
13,769 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
217
States / cities
Cullman, Alabama • Dothan, Alabama • Fairhope, Alabama + 214 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 5, 2026, 2:24 PM EDT
Not listed No phase listed Observational

Exercise Capacity Before and After AF Ablation in Patients With HFpEF

NCT05376748
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 110 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 5, 2026, 2:24 PM EDT
Active, not recruiting No phase listed Observational

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

NCT04033510
View directory record Official record
Conditions
Atrial Fibrillation, Cognitive Symptom, Executive Dysfunction, Cognitive Change, Cognitive Impairment, Cognitive Impairment, Mild
Interventions
Standard of Care Interventions to convert patient from atrial fibrillation to normal rhythm
Other
Lead sponsor
David Brunk, PA-C, MMS
Other
Eligibility
35 Years to 80 Years
Enrollment
600 participants
Timeline
2019 – 2027
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 5, 2026, 2:24 PM EDT
Completed Not applicable Interventional Results available

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

NCT02731326
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
AliveCor, Behavioral Altering Messaging
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 5, 2026, 2:24 PM EDT