Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 5, 2026, 11:20 PM EDT

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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Conditions
Ductus Arteriosus, Patent
Interventions
Percutaneous Patent Ductus Arteriosus Closure (PPC), Responsive Management Intervention, Echocardiogram, cardiac
Device · Combination Product · Diagnostic Test
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
7 Days to 32 Days
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 19 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Long-term Safety Study of the GORE® HELEX® Septal Occluder

NCT00581308
Conditions
Septal Defect, Atrial
Interventions
GORE® HELEX® Septal Occluder
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
Not listed
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Patent Foramen Ovale
Interventions
PFO Closure
Other
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Vascular Closure, Pacemaker Implantation, Leadless Pacemaker
Interventions
percutaneous suture mediated closure, Figure of Eight Suture
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Septal Defect, Atrial
Interventions
GORE® CARDIOFORM Septal Occluder
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Recruiting Not applicable Interventional

Tract Closure in PCNL

NCT07668817
Conditions
Nephrolithiasis
Interventions
Floseal, Surgicel, Surgiflo, Balloon Tamponade
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Peripheral Vascular Disease, Cardiovascular Disease
Interventions
Vessel Closure (StarClose™)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 85 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
11
States / cities
La Jolla, California • Atlanta, Georgia • Peoria, Illinois + 8 more
Active, not recruiting Not applicable Interventional

PREEMIE: Study for Treatment of PDA in Premature Infants

NCT06587282
Conditions
Patent Ductus Arteriosus (PDA)
Interventions
Bloom Micro Occluder System
Device
Lead sponsor
Merit Medical Systems, Inc.
Industry
Eligibility
5 Days and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
9
States / cities
Sacramento, California • San Diego, California • Hollywood, Florida + 6 more
Conditions
Diabetic Foot Ulcer
Interventions
Tenex TXB MicroTip Ultrasound system plus SOC, Standard of Care for diabetic foot ulcer
Device · Other
Lead sponsor
Tenex Health Inc.
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Mobile, Alabama • St. George, Utah
Completed Not applicable Interventional

PerQseal®+ Early Feasibility Study

NCT05163548
Conditions
Percutaneous Large Hole Vascular Closure
Interventions
PerQseal Plus Device
Device
Lead sponsor
Vivasure Medical Limited
Industry
Eligibility
19 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
5
States / cities
Ridgewood, New Jersey • New York, New York • Stony Brook, New York + 2 more
Completed No phase listed Observational Results available

VASCADE ANTEGRADE-PVD Post-Market Registry

NCT02948257
Conditions
Surgical Wound
Interventions
Cardiva Medical VASCADE VCS
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
5
States / cities
Houma, Louisiana • Tupelo, Mississippi • Wilmington, North Carolina + 2 more
Completed No phase listed Observational

Nit-Occlud PDA Post-Approval Study

NCT02100683
Conditions
Patent Ductus Arteriosus (PDA)
Interventions
PDA Coil
Device
Lead sponsor
PFM Medical, Inc
Industry
Eligibility
6 Months to 21 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
11
States / cities
Loma Linda, California • Los Angeles, California • Madera, California + 8 more
Completed Not applicable Interventional Results available

MANTA Percutaneous Vascular Closure Device - The SAFE MANTA Study

NCT02908880
Conditions
Femoral Arteriotomy Closure
Interventions
MANTA vascular closure device
Device
Lead sponsor
Essential Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
18
States / cities
San Diego, California • Washington D.C., District of Columbia • Evanston, Illinois + 14 more
Active, not recruiting Not applicable Interventional

PerQseal® Clinical Study

NCT05653336
Conditions
Percutaneous Large Hole Vascular Closure
Interventions
PerQseal® Closure Device System
Device
Lead sponsor
Vivasure Medical Limited
Industry
Eligibility
19 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
15
States / cities
Scottsdale, Arizona • La Jolla, California • Bangor, Maine + 12 more
Conditions
Atrial Fibrillation
Interventions
VASCADE MVP VVCS
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
497 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
San Luis Obispo, California • Washington D.C., District of Columbia • Burlington, Massachusetts + 1 more
Conditions
Pain, Postoperative
Interventions
Pre-op percutaneous rectus sheath block, Intra-operative rectus sheath block, Ropivacaine
Procedure · Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
3 Years to 18 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Conditions
Medical Device, Angiography
Interventions
Boomerang closure device
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Surgical Wound
Interventions
Manual compression, Cardiva VASCADE™ Vascular Closure System
Other · Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Fairhope, Alabama • Newark, Delaware • Melbourne, Florida + 17 more
Conditions
Stroke
Interventions
Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device
Device
Lead sponsor
Coherex Medical
Industry
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
23
States / cities
Birmingham, Alabama • Chandler, Arizona • Los Angeles, California + 18 more
Conditions
Cardiac Catheterization
Interventions
suture mediated closure
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional

NIT-OCCLUD PDA Phase II Sentinel Trial

NCT00828334
Conditions
Ductus Arteriosus, Patent
Interventions
Transcatheter PDA Coil
Device
Lead sponsor
PFM Medical, Inc
Industry
Eligibility
6 Months to 21 Years
Enrollment
357 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
15
States / cities
Los Angeles, California • Madera, California • Orange, California + 12 more
Conditions
Atrial Fibrillation, Atrial Arrhythmia
Interventions
Data collection
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
10
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts + 4 more
Conditions
Percutaneous Large Hole Vascular Closure
Interventions
PPCI, Cardiogenic shock
Device
Lead sponsor
Vivasure Medical Limited
Industry
Eligibility
19 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Ridgewood, New Jersey • Buffalo, New York • Stony Brook, New York + 1 more
Conditions
PFO, PFO - Patent Foramen Ovale, Cryptogenic Stroke, Patent Foramen Ovale, PFO-associated Stroke
Interventions
Recross P3 Occluder (P3O) System
Device
Lead sponsor
Recross Cardio, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
5
States / cities
Los Angeles, California • Gainsville, Florida • Boston, Massachusetts + 2 more