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ClinicalTrials.gov public records Last synced Sep 24, 2026, 12:06 PM EDT

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Showing 1–11 of 11 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
DENT IMPLANTS, LASER
Interventions
Conventional mechanical therapy, Saline, Methylene Blue, Light emitting laser, Non-light emitting laser
Procedure · Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Peri Implantitis
Interventions
Staged peri-implant debridement and regeneration, Simultaneous peri-implant debridement and regeneration
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Peri-Implantitis
Interventions
Minocycline HCl Microspheres
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
10
States / cities
Baltimore, Maryland • Boston, Massachusetts • Ann Arbor, Michigan + 7 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis

NCT03127228
Conditions
Peri-Implantitis
Interventions
Standard mechanical debridement, Er:YAG laser-assisted debridement
Other · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Peri-implantitis
Interventions
Resective surgery with implantoplasty, Resective surgery with mechanical debridement
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase

NCT03544515
Conditions
Peri-Implantitis
Interventions
Er,Cr:YSGG laser, Scaling, Inactive Er,Cr:YSGG
Device · Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Laser Therapy Treatment of Peri-implantitis.

NCT01972399
Conditions
Peri-implantitis
Interventions
Laser, Mechanical debridement
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Peri-Implantitis
Interventions
Minocycline HCl Microspheres
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
9
States / cities
Los Angeles, California • Gainsville, Florida • Augusta, Georgia + 6 more
Conditions
Peri-Implantitis
Interventions
2.5 mg Chlorhexidine gluconate chip
Drug
Lead sponsor
Dexcel Pharma Technologies Ltd.
Industry
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
6
States / cities
Baltimore, Maryland • Boston, Massachusetts • Ann Arbor, Michigan + 2 more
Completed Not applicable Interventional Accepts healthy volunteers

Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study

NCT03917264
Conditions
Peri-Implantitis
Interventions
Peri-implantitis debridement, Dental hygiene procedures
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
25 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
San Antonio, Texas • Seattle, Washington
Conditions
Periodontal Disease, Periodontal Surgery
Interventions
Blood samples for inflammatory markers, periodontal surgery, Periodontal maintenance, Non-surgical deep cleaning
Other · Procedure
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio