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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:14 AM EDT

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Showing 1–24 of 374 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Physical Fatigue Clear all
Active, not recruiting Not applicable Interventional

Lupus Intervention for Fatigue Trial

NCT02653287
View directory record Official record
Conditions
Fatigue, Physical Activity, Lupus Erythematosus, Systemic
Interventions
Experimental, Control
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Terminated Not applicable Interventional

Efficacy of a Home-Based Exercise Program for Heart Failure

NCT01407185
View directory record Official record
Conditions
Heart Failure
Interventions
Resistive Exercise Training
Other
Lead sponsor
Catholic Home Care
Other
Eligibility
60 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Holtsville, New York
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Treatment Protocol for PD Fatigue Management With CBT

NCT03747848
View directory record Official record
Conditions
Parkinson Disease
Interventions
CBT group
Behavioral
Lead sponsor
New York Institute of Technology
Other
Eligibility
21 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study

NCT03797378
View directory record Official record
Conditions
Spinal Cord Injuries, Traumatic Brain Injury, Spina Bifida, Cerebral Palsy, Stroke, Parkinson Disease, Multiple Sclerosis
Interventions
eM2M
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

The Ability of Electronic Patient Symptom Reporting to Reduce Symptom Burden During Hospitalization for Chemotherapy

NCT02574897
View directory record Official record
Conditions
Stem Cell Transplantation, Hematopoietic
Interventions
Electronic symptom survey, Blinded Electronic Symptom Survey
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 75 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease

NCT03211689
View directory record Official record
Conditions
Primary Immune Deficiency Disorder, Common Variable Immunodeficiency, Specific Antibody Deficiency, Hypergammaglobulinemia
Interventions
Exercise Program
Other
Lead sponsor
Stockton University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Galloway, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 19, 2026, 10:14 AM EDT
Completed No phase listed Observational

Quality of Life in Patients Who Have Undergone Stem Cell Transplant

NCT00128960
View directory record Official record
Conditions
Long Term Psychological Affects on HSCT
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional Results available

Insomnia Self-Management in Heart Failure

NCT02660385
View directory record Official record
Conditions
Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive, Sleep Initiation and Maintenance Disorders, Chronic Insomnia, Disorders of Initiating and Maintaining Sleep, Fatigue, Pain, Depressive Symptoms, Sleep Disorders, Anxiety
Interventions
Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 19, 2026, 10:14 AM EDT
Not yet recruiting Not applicable Interventional

Efficacy Of An Inpatient Yoga Therapy Program For Cancer Patients

NCT07776587
View directory record Official record
Conditions
Cancer
Interventions
Yoga Therapy (YT)
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

NCT07759921
View directory record Official record
Conditions
Colorectal Cancer, Metastatic Colorectal Cancer (CRC)
Interventions
Couple-based Mindfulness Intervention, Health and Wellness Education Control Condition
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Coping Together: Couple-based Interventions for Cancer

NCT04590885
View directory record Official record
Conditions
Advanced Cancer
Interventions
Couple Communication Skills Training, Healthy Lifestyle Information
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Physical Activity to Maintain Quality of Life and Physical Function in Women With Metastatic Breast Cancer: a Pilot Study

NCT02682836
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Walk with Ease
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 6, 2022 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Women With Breast Cancer to Prepare for Treatment (The Prepare Study)

NCT07221071
View directory record Official record
Conditions
Breast Cancer, Mindfulness
Interventions
Mindfulness Arm, Control group placebo
Behavioral · Other
Lead sponsor
Endeavor Health
Other
Eligibility
20 Years to 85 Years · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Programs to Support You During Chemotherapy (Pro-You)

NCT02148406
View directory record Official record
Conditions
Depressive Symptoms, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Stage IIA Colon Cancer, Stage IIA Rectal Cancer, Stage IIB Colon Cancer, Stage IIB Rectal Cancer, Stage IIC Colon Cancer, Stage IIC Rectal Cancer, Stage IIIA Colon Cancer, Stage IIIA Rectal Cancer, Stage IIIB Colon Cancer, Stage IIIB Rectal Cancer, Stage IIIC Colon Cancer, Stage IIIC Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer
Interventions
Yoga Skills Training (YST), questionnaire administration, fatigue and depressive symptom assessment and management, psychological stress assessment, laboratory biomarker analysis, Attention Control
Behavioral · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 19, 2026, 10:14 AM EDT
Not yet recruiting Phase 1 Interventional

A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss

NCT07663630
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC), Cachexia
Interventions
ponsegromab, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Decatur, Illinois • O'Fallon, Illinois • Garland, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Patient-Centered Physical Activity Program for Hemodialysis Patients

NCT07080593
View directory record Official record
Conditions
Hemodialysis
Interventions
Novel Physical Activity Program, Standard of Care Physical Activity Program
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
3
States / cities
Bolingbrook, Illinois • Oak Brook, Illinois • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 19, 2026, 10:14 AM EDT
Recruiting No phase listed Observational

A Study of Neurocognitive Tests and Questionnaires for People With Head and Neck Cancer Who Are Undergoing Radiation Therapy

NCT05207098
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Neurocognitive Tests, Questionnaires
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Phase 2 Interventional

Exercise Plus Epoetin Alfa in Treating Cancer Patients Who Have Anemia-Related Fatigue

NCT00004914
View directory record Official record
Conditions
Anemia, Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
epoetin alfa, physical therapy
Biological · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 6, 2012 · Synced Oct 19, 2026, 10:14 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

The Effect of Milnacipran on Fatigue and Quality of Life in Lupus Patients

NCT01359826
View directory record Official record
Conditions
Systemic Lupus Erythematosus, Widespread Pain, Fibromyalgia
Interventions
Milnacipran
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2015 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Caregiver Support in the Context of Multiple Chronic Conditions

NCT04090749
View directory record Official record
Conditions
Caregiver Burnout
Interventions
Caregiver-Support
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 19, 2026, 10:14 AM EDT
Active, not recruiting Not applicable Interventional

A Study Comparing Mindfulness Apps to Decrease Anxiety in People With Lung Cancer

NCT06008574
View directory record Official record
Conditions
Lung Cancer
Interventions
AmDTx-PCSP, AmDTx-2048, Questionnaires
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2

NCT05200858
View directory record Official record
Conditions
Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome, Widespread Chronic Pain, Fatigue Syndrome, Chronic, Gait, Unsteady
Interventions
TENS - high-dose, TENS - low-dose
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Oct 19, 2026, 10:14 AM EDT
Completed Phase 1 Interventional

Interactive Care Plan for the Monitoring of Symptoms and Recovery in Patients With Stage 0-III Breast Cancer

NCT04693338
View directory record Official record
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
Interventions
Quality-of-Life Assessment, Questionnaire Administration, Supportive Care
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 19, 2026, 10:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Sleep and Teamwork in EMS Study

NCT04456764
View directory record Official record
Conditions
Fatigue, Sleep
Interventions
SaFTiE, Attention Placebo Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
708 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 19, 2026, 10:14 AM EDT