Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Knee Osteoarthritis
Interventions
CNTX-4975-05, Lidocaine without epinephrine, ElastoGel, Breg Ice Water Pump
Drug · Device
Lead sponsor
Centrexion Therapeutics
Industry
Eligibility
40 Years to 95 Years
Enrollment
854 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
28
States / cities
Birmingham, Alabama • Peoria, Arizona • Tucson, Arizona + 24 more
Conditions
Osteoarthritis
Interventions
Osteoarthritis Physical Activity Care Pathway
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Interventions
Exercise for Knee Osteoarthritis, Compact seated elliptical exercise machine- Cubii JR-1
Other · Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
50 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Not yet recruiting Not applicable Interventional

Boosting Exercise Adherence in Knee Osteoarthritis

NCT07219732
Conditions
Osteoarthritis, Knee
Interventions
Usual PT Care (UC), BOOST-OA
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Results available

STepped Exercise Program for Knee OsteoArthritis

NCT02653768
Conditions
Osteoarthritis, Knee
Interventions
Stepped Exercise Program, Arthritis Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
345 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)

NCT01328340
Conditions
Knee Osteoarthritis
Interventions
High-speed power training, Slow-speed strength training
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
55 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Knee Osteoarthritis
Interventions
Physical Therapy
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
Not listed
Enrollment
18 participants
Timeline
2018
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

TENS Effectiveness and Knee Osteoarthritis in Humans

NCT01354054
Conditions
Knee Osteoarthritis
Interventions
High Frequency TENS, Low frequency TENS, Placebo TENS
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
30 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Knee Osteoarthritis, Obese, Depression
Interventions
Fisetin, GetHealthy-OA mind-body program, Placebo oral capsule, Health education booklet
Drug · Behavioral
Lead sponsor
Cale Andrew Jacobs, PhD
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Lexington, Kentucky
Conditions
Knee Osteoarthritis
Interventions
Physical Therapy for knee OA, Cognitive Behavioral Therapy for Pain CBT-P, Enhanced Treatment as Usual
Procedure · Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional

Remote Tai Chi for Knee Osteoarthritis

NCT06384898
Conditions
Knee Osteoarthritis
Interventions
Remote Tai Chi
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
50 Years to 100 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Knee Osteoarthritis
Interventions
DoD/VA CPG Core Set + PT, DoD/VA CPG Core Set
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
3
States / cities
San Antonio, Texas • Tacoma, Washington
Terminated Not applicable Interventional Results available

The Effect of AposTherapy on Knee Pain

NCT03171168
Conditions
Knee Osteoarthritis, Knee Pain
Interventions
AposTherapy, Traditional Physical Therapy
Device · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Knee Osteoarthristis, ACL Injuries, Post-Traumatic
Interventions
extracorporeal shockwave therapy (ESWT), Sham Comparator
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Completed Not applicable Interventional Results available

Wearable Sensors in Knee OA

NCT04243096
Conditions
Knee Osteoarthritis
Interventions
Exercise-based Physical Therapy
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
50 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Results available

Optimization of Synvisc-One for Knee OA

NCT02029703
Conditions
Knee Osteoarthritis
Interventions
Synvisc-One Injection, Sham Injection
Device · Other
Lead sponsor
Elaine Husni
Other
Eligibility
21 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Weston, Florida
Conditions
Osteoarthritis
Interventions
Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
Procedure · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
7
States / cities
Chicago, Illinois • Boston, Massachusetts • Rochester, Minnesota + 4 more
Completed Not applicable Interventional Results available

Tai Chi Mind-Body Therapy for Knee Osteoarthritis

NCT00362453
Conditions
Knee Osteoarthritis
Interventions
Tai Chi versus Attention Control
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
55 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional

Yoga Versus Exercises for Managing OA

NCT02525341
Conditions
Knee Osteoarthritis
Interventions
Hatha yoga, Aerobic and strengthening exercises, General education
Other
Lead sponsor
University of Minnesota
Other
Eligibility
60 Years to 100 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Osteoarthritis
Interventions
OA-PCP Intervention, Attention Control
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Knee Osteoarthritis, Mind-body Exercise
Interventions
Tai chi exercise
Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Knee Osteoarthritis
Interventions
ROAM OA Single Upright Knee Brace, Ossur Unloader One Knee Brace or Standard of Care
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
40 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Knee Osteoarthritis, Chronic Pain
Interventions
Technology-implemented exercise therapy, Traditional Physical Therapy
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Effectiveness Trial for Evaluating IAHA for PFPS

NCT01811654
Conditions
Patellofemoral Pain Syndrome
Interventions
Intra-Articular Hyaluronic Acid-Euflexxa
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York