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Conditions: Atopic Dermatitis
Interventions: PRN473 (SAR444727), Placebo; Drug
Lead sponsor: Principia Biopharma, a Sanofi Company; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 9
States / cities: Long Beach, California • Los Angeles, California • Miami, Florida + 6 more

Conditions: Pruritus, Atopic Dermatitis
Interventions: difelikefalin 0.25 mg, difelikefalin 0.5 mg, TCS Cream, Placebo, Vehicle Cream; Drug
Lead sponsor: Cara Therapeutics, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 287 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 61
States / cities: Scottsdale, Arizona • Fort Smith, Arkansas • Rogers, Arkansas + 56 more

Conditions: Pain
Interventions: HKT-500 Ketoprofen Topical Patch, Placebo Patch; Drug · Other
Lead sponsor: Hisamitsu Pharmaceutical Co., Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 368 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 35
States / cities: Birmingham, Alabama • Tempe, Arizona • Fullerton, California + 30 more

Conditions: EGFRI Induced Acneiform Lesions
Interventions: LUT014 Gel (Dose 1), LUT014 Gel (Dose 2), Placebo; Drug
Lead sponsor: Lutris Pharma Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 17
States / cities: Glendale, California • Santa Monica, California • Miami, Florida + 12 more

Conditions: Needle Phobia
Interventions: Lidocaine patch 4%; Drug
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Molluscum Contagiosum, Skin Disease
Interventions: cantharidin's vehicle, Cantharidin 0.7%; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 5 Years to 10 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Postmenopausal Syndrome
Interventions: Estrogen, Progesterone, Placebo; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 55 Years to 75 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Atopic Dermatitis
Interventions: Placebo, Upadacitinib, Topical corticosteroids (TCS); Drug
Lead sponsor: AbbVie; Industry
Eligibility: 12 Years to 75 Years
Enrollment: 1,533 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2030
U.S. locations: 59
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 51 more

Conditions: Anal High Grade Squamous Intraepithelial Lesion, Anal Precancerous Condition, AIN 2/3, HPV Infection, Anal Dysplasia, HPV Disease
Interventions: Artesunate, Placebo; Drug
Lead sponsor: Frantz Viral Therapeutics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • New York, New York

Conditions: Rotator Cuff Tendonitis, Bicipital Tendonitis, Subdeltoid Bursitis of the Shoulder, Subacromial Bursitis of the Shoulder, Medial Epicondylitis of the Elbow, Lateral Epicondylitis of the Elbow, DeQuervain's Tenosynovitis of the Wrist
Interventions: diclofenac sodium, Matching Placebo; Drug
Lead sponsor: Cerimon Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 308 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Osteoarthritis Pain of the Knee
Interventions: Diclofenac sodium active topical patch, Placebo patch; Drug
Lead sponsor: Noven Pharmaceuticals, Inc.; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 370 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 10
States / cities: Little Rock, Arkansas • Clearwater, Florida • Doral, Florida + 7 more

Conditions: Seborrheic Keratosis (SK)
Interventions: A-101 25%, A-101 32.5%, A-101 40%, A-101 Vehicle; Drug
Lead sponsor: Aclaris Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Austin, Texas

Conditions: AIDS-related Kaposi Sarcoma, Recurrent Kaposi Sarcoma
Interventions: halofuginone hydrobromide, placebo, laboratory biomarker analysis, pharmacological study; Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 16 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Rockville, Maryland

Conditions: Dermatitis, Atopic, Eczema
Interventions: Investigational OTC Cream, Cosmetic Eczema Cream, 0.05% Desonide Cream, Placebo Cream; Drug · Other
Lead sponsor: Procter & Gamble Beauty; Industry
Eligibility: 12 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: Acute Pain, Soft Tissue Injury
Interventions: Diclofenac Sodium, Matching Placebo Patch; Drug
Lead sponsor: Cerimon Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 407 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Postherpetic Neuralgia, Pain
Interventions: Transdermal/Patch (Bupivacaine TTS [Eladur™]); Drug
Lead sponsor: Durect; Industry
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 7
States / cities: La Jolla, California • Loma Linda, California • Santa Monica, California + 4 more

Conditions: Vulvar Diseases, HPV Infection, Vulvar HSIL, Pre-Cancerous Dysplasia, HPV Disease, VIN, Usual Type, VIN 2 of Usual Type, VIN 3 of Usual Type, Vin II, Vin III, VIN Grade 2, VIN Grade 3, High Grade Intraepithelial Neoplasia
Interventions: Artesunate ointment, Placebo ointment; Drug
Lead sponsor: Frantz Viral Therapeutics, LLC; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 5
States / cities: Fort Myers, Florida • Indianapolis, Indiana • Cleveland, Ohio + 1 more

Conditions: Knee Osteoarthritis, CBD, Osteoarthritis
Interventions: Topical CBD Patch, Placebo Patch; Drug · Other
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Healthy Volunteers
Interventions: PBI-100 Topical Cream, Positive Control - Sodium laurel sulfate (SLS), PBI-100 Topical Cream, Vehicle, Negative Control; Drug · Other
Lead sponsor: Pyramid Biosciences; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Newtown Square, Pennsylvania

Conditions: Sprain, Strain
Interventions: Ketoprofen Topical Patch 20%; Drug
Lead sponsor: APR Applied Pharma Research s.a.; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Vitamin D Deficiency
Interventions: Transdermal D Patch, Oral vitamin D3, Placebo patch, Oral placebo; Dietary Supplement
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Ankle Sprains
Interventions: MRX-7EAT, Placebo, Lidocaine, Etodolac; Drug
Lead sponsor: MEDRx USA, Inc.; Industry
Eligibility: 14 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 33
States / cities: Phoenix, Arizona • North Little Rock, Arkansas • Chico, California + 30 more

Conditions: Osteoarthritis of the Knee
Interventions: HP-5000 Topical Patch, HP-5000 Placebo Patch, Saline Patch; Drug
Lead sponsor: Noven Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Fair Lawn, New Jersey

Conditions: Actinic Keratoses
Interventions: Test Product (A): Fluorouracil Cream, 5% topical cream, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India; Drug
Lead sponsor: Encube Ethicals Pvt. Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 458 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 7
States / cities: Bakersfield, California • Cerritos, California • Lauderdale Lakes, Florida + 3 more

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Phase 2a Study of the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

HKT-500 in Adult Patients With Shoulder Pain

LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC

Lidocaine Patch vs Intradermal Lidocaine for Epidural Needle Insertion Pain

Efficacy of Cantharidin in Molluscum Contagiosum

Evaluating the Roles of Estrogen and Progesterone in Heart Metabolism

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL

Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis

A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee

Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis

Halofuginone Hydrobromide in Treating Patients With HIV-Related Kaposi's Sarcoma

Efficacy and Tolerability of New Topical Formulations in Subjects With Atopic Dermatitis

Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Soft Tissue Injuries (TAPED)

Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

The Use of Cannabinoid Patch for Knee Osteoarthritis

A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants

Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain

Evaluation of a Transdermal Vitamin D3 Delivery System, D3forME

MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains

Irritation and Sensitization Study of HP-5000 Topical System

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis