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ClinicalTrials.gov public records Last synced Sep 30, 2026, 5:42 PM EDT

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Showing 25–48 of 867 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Placebo and sham Clear all
Completed Not applicable Interventional

Anti-Inflammatory Effects Of Frequency Specific Microcurrent (FSM) In Osteoarthritic Adults

NCT06390137
View directory record Official record
Conditions
Osteoarthritis
Interventions
Frequency Specific Microcurrent, Sham microcurrent treatment
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Lakeland, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Sep 30, 2026, 5:42 PM EDT
Not listed Phase 1Phase 2 Interventional

LIWA for Treatment of Alzheimer Patients

NCT02204969
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lithia water, Transcranial Magnetic stimulation
Dietary Supplement · Device
Lead sponsor
American Society Of Thermalism And Climatology Inc
Other
Eligibility
50 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 6, 2015 · Synced Sep 30, 2026, 5:42 PM EDT
Terminated Not applicable Interventional

A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD)

NCT02479906
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Deep TMS System, Sham Treatment
Device
Lead sponsor
Brainsway
Industry
Eligibility
22 Years to 68 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
12
States / cities
Los Angeles, California • Palo Alto, California • San Diego, California + 8 more
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Sep 30, 2026, 5:42 PM EDT
Enrolling by invitation Not applicable Interventional

Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional Recovery

NCT06641271
View directory record Official record
Conditions
Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis
Interventions
Closed Loop Trans-Auricular Vagus Nerve Stimulation System, Placebo
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Not applicable Interventional Results available

Theta Burst Stimulation in Young Adults With Depression

NCT03737032
View directory record Official record
Conditions
Depression
Interventions
Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation, Sham Theta Burst Stimulation
Device
Lead sponsor
Erika Forbes
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension

NCT02250651
View directory record Official record
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
Bimatoprost SR, Sham: Applicator Without Needle, Active Comparator: Timolol 0.5%, Timolol Vehicle (placebo)
Drug · Other
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
528 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
51
States / cities
Dothan, Alabama • Chandler, Arizona • Fayetteville, Arkansas + 47 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Sep 30, 2026, 5:42 PM EDT
Active, not recruiting Phase 2 Interventional

Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer

NCT03092856
View directory record Official record
Conditions
Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Cancer, Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer
Interventions
Anti-OX40 Antibody PF-04518600, Axitinib, Laboratory Biomarker Analysis, Placebo
Biological · Drug · Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
9
States / cities
Los Angeles, California • Newport Beach, California • Sacramento, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Not applicable Interventional Results available

Understanding the Sleep Apnea/Insomnia Interaction

NCT01824472
View directory record Official record
Conditions
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Interventions
CPAP, CBT, sham CPAP, CC
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Paracervical Block for Pain Associated With Laminaria Insertion

NCT02454296
View directory record Official record
Conditions
Pain
Interventions
Paracervical Block with lidocaine, Sham paracervical block
Drug
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Sep 30, 2026, 5:42 PM EDT
Not yet recruiting Not applicable Interventional

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

NCT07079969
View directory record Official record
Conditions
Chronic Knee Pain
Interventions
Photobiomodulation therapy (PBM) device, Sham PBM device
Device
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 30, 2026, 5:42 PM EDT
Terminated Phase 2 Interventional

Effectiveness and Safety Study for JNJ-18054478 in Asthma Patients.

NCT00530166
View directory record Official record
Conditions
Asthma
Interventions
JNJ-18054478, sham comparator
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
29
States / cities
Scottsdale, Arizona • Long Beach, California • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2014 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Phase 1 Interventional

A Study of Lung Clearance After Hypertonic Saline Delivery Using the tPAD Device

NCT02141191
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
inhaled hypertonic saline (7%)
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Sep 30, 2026, 5:42 PM EDT
Terminated Not applicable Interventional

Long Duration Therapeutic Ultrasound on Tendon Injuries

NCT02340273
View directory record Official record
Conditions
Tendon Injuries, Musculoskeletal Pain
Interventions
Therapeutic ultrasound, Placebo therapeutic ultrasound
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Milford, Connecticut • Trumbull, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Early Phase 1 Interventional Results available

Safety of Transcranial Direct Current Stimulation in Pediatric Hemiparesis

NCT01636661
View directory record Official record
Conditions
Hemiparesis
Interventions
tDCS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
8 Years to 17 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 9, 2015 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain

NCT03003715
View directory record Official record
Conditions
Trigeminal Neuropathic Pain
Interventions
PET Scans, transcranial direct current stimulation (tDCS), MRI, sham tDCS (prior to real tDCS)
Procedure · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Sep 30, 2026, 5:42 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage

NCT07770685
View directory record Official record
Conditions
Glaucoma
Interventions
ASP2767, Sham ASP2767, Prophylactic Regimen A, Prophylactic Regimen B, Placebo for prophylactic regimen
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Sep 30, 2026, 5:42 PM EDT
Terminated Phase 2 Interventional Results available

Regorafenib Eye Drops: Investigation of Efficacy and Safety in Neovascular Age Related Macular Degeneration

NCT02222207
View directory record Official record
Conditions
Macular Degeneration
Interventions
Regorafenib, ophthalmic oily suspension (BAY73-4506), Sham IVT, Ranibizumab, Placebo
Drug · Procedure
Lead sponsor
Bayer
Industry
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
37
States / cities
Tucson, Arizona • Arcadia, California • Beverly Hills, California + 34 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Early Phase 1 Interventional Results available

Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults

NCT03944954
View directory record Official record
Conditions
Neurosciences, Substance-Related Disorders, Behavior Problem
Interventions
Placebo TMS Sham, Marinol 10Mg Capsule TMS Sham, Marinol 30Mg Capsule TMS Sham, Placebo TMS Real, Marinol 10Mg Capsule TMS Real, Marinol 30Mg Capsule TMS Real
Device · Drug · Other
Lead sponsor
Michael J. Wesley, PhD
Other
Eligibility
18 Years to 34 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Role of 905-nm Laser Light in the Delay of Muscle Fatigue

NCT03461731
View directory record Official record
Conditions
Muscle Fatigue
Interventions
Control, 800 nm laser, combination laser, 905 nm laser
Device
Lead sponsor
College of Charleston
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Sep 30, 2026, 5:42 PM EDT
Suspended Not applicable Interventional

Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia

NCT01823237
View directory record Official record
Conditions
Dystonia
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Sep 30, 2026, 5:42 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Red Light LED Therapy on Body Contouring

NCT03470272
View directory record Official record
Conditions
Obesity
Interventions
FB Professional LED Red light therapy, Effects of Red Light LED Therapy on Body Contouring
Device
Lead sponsor
Manamed Inc.
Industry
Eligibility
18 Years to 77 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New Port Richey, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Sep 30, 2026, 5:42 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use

NCT02927236
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
22 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 30, 2026, 5:42 PM EDT
Completed Not applicable Interventional

The Effect of Intraneural Facilitation Therapy on Diabetic Patients With Peripheral Neuropathy

NCT04025320
View directory record Official record
Conditions
Diabetic Neuropathy
Interventions
Intraneural Facilitation, Sham
Other
Lead sponsor
Loma Linda University
Other
Eligibility
50 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Sep 30, 2026, 5:42 PM EDT
Withdrawn Not applicable Interventional

TENS Treatment Plus Ibuprofen for the Treatment of Acute Back Pain in the ED

NCT02611583
View directory record Official record
Conditions
Low Back Pain
Interventions
TENS
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Sep 30, 2026, 5:42 PM EDT