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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:53 AM EDT

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Showing 25–48 of 201 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive Affect Clear all
Completed Phase 1Phase 2 Interventional Results available

The University of Michigan PCOS Intervention Using Nutritional Ketosis

NCT03987854
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
diet and lifestyle program
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skills to Enhance Positivity in Young Adults

NCT06621992
View directory record Official record
Conditions
Positive Affect, Mindfulness, Gratitude, Savoring, Depression
Interventions
Skills to Enhance Positivity, Treatment as Usual
Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional

The Effect of Psychologically Informed Education in Adolescents With Patellofemoral Pain

NCT03897907
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Psychologically Informed Education Video, Anatomy Education Video
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 29, 2026, 4:53 AM EDT
Not listed No phase listed Observational

Psychosocial Determinants of Medication Adherence in Hypertensive African Americans

NCT00195182
View directory record Official record
Conditions
Hypertension
Interventions
Self affirmation and positive affect induction vs. control
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2008 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).

NCT06526052
View directory record Official record
Conditions
Prevention, Control
Interventions
Mindfulness Program, Active Comparator
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
12 Years to 17 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Evanston, Illinois • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain

NCT07137715
View directory record Official record
Conditions
Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
Interventions
Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

NCT02488863
View directory record Official record
Conditions
Musculoskeletal Pain, Pain, Chronic
Interventions
MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires, Physical and Cognitive Function Testing
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
4
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 2 Interventional

A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics

NCT01713764
View directory record Official record
Conditions
Diabetes Type II
Interventions
Low Carbohydrate Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2013 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Therapeutic Effects of the Processing of Positive Memories Technique on Posttrauma Health

NCT06680193
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Processing of Positive Memories Technique
Behavioral
Lead sponsor
University of North Texas, Denton, TX
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Denton, Texas
Source: ClinicalTrials.gov public record
Updated Nov 8, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-based Implementation for the Science of Enhancing Resilience Study

NCT02603133
View directory record Official record
Conditions
Burnout, Professional, Resilience, Psychological
Interventions
Three Good Things, Gratitude, Random Acts of Kindess, Awe, 1 Good Chat
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 85 Years
Enrollment
2,650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
9
States / cities
Palo Alto, California • Stanford, California • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Factorial Trial Testing Guided Thinking Tasks to Optimize a Physical Activity Intervention

NCT05235360
View directory record Official record
Conditions
Physical Inactivity
Interventions
Episodic future thinking, Positive affect imagery, Action planning, High dose, Recent thinking, Neutral imagery, Low dose
Behavioral
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 64 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Assessment of Emotion Regulation Strategies Used When Suicidal

NCT05722197
View directory record Official record
Conditions
Suicidal Ideation, Treatment Refusal, Emotion Regulation
Interventions
Crisis Response Planning and Lethal Means Safety Counseling
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Pilot Study of Changing Exercise and Physical Activity Behavior in Asthma Patients

NCT00227162
View directory record Official record
Conditions
Asthma
Interventions
Group 1, Group 2, Group 3
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 29, 2026, 4:53 AM EDT
Completed No phase listed Observational

Role of Positive Affect in Adjustment to HIV

NCT00582023
View directory record Official record
Conditions
HIV Infections
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

NCT06570642
View directory record Official record
Conditions
Physical Inactivity, Overweight or Obesity, Cancer
Interventions
Physical Activity Goals mHealth Intervention, TYPE/CONTEXT enhancement, SAVOR enhancement
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral Cavity

NCT01265849
View directory record Official record
Conditions
Squamous Cell Carcinoma of the Oral Cavity, Squamous Cell Carcinoma of the Soft Palate
Interventions
LI, Cyclophosphamide, Indomethacin, Zinc, Surgery, Cisplatin, Radiotherapy
Biological · Drug · Dietary Supplement + 2 more
Lead sponsor
CEL-SCI Corporation
Industry
Eligibility
18 Years and older
Enrollment
928 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
5
States / cities
Springfield, Illinois • Detroit, Michigan • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2022 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

NCT06005285
View directory record Official record
Conditions
Autism
Interventions
Early Start Denver Model (ESDM), Early Intensive Behavioral Intervention (EIBI)
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
12 Months and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Testing the Effectiveness of an Online Behavioral Intervention in Reducing Loneliness

NCT04112225
View directory record Official record
Conditions
Psychological Distress, Loneliness
Interventions
Happify
Behavioral
Lead sponsor
Happify Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
890 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional

A Hybrid Type II Trial of the Optimizing Resilience and Coping With HIV Through Internet Delivery in Ryan White Clinics in Chicago

NCT05123144
View directory record Official record
Conditions
People Living With HIV
Interventions
BHS+ORCHID
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Phase 2 Interventional

Pain Reprocessing Therapy in Post-Operative Knee Pain

NCT06800209
View directory record Official record
Conditions
Pain, Chronic, Knee Pain Chronic
Interventions
Pain reprocessing therapy (PRT), Usual care
Behavioral · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Eat Breathe Thrive, a Yoga-Based Program

NCT03348345
View directory record Official record
Conditions
Eating Disorder Symptom
Interventions
Eat Breathe Thrive
Behavioral
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 65 Years
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Positive Psychology Intervention to Treat Diabetes Distress in Teens With Type 1 Diabetes

NCT03845465
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Positive Affect + Education, Education
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
13 Years to 17 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Not yet recruiting Not applicable Interventional

Standardized Adaptive Music Medicine for Suicidality

NCT07610785
View directory record Official record
Conditions
Suicidal Thoughts and Behaviors
Interventions
STAMM-S
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 35 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Not applicable Interventional

Examining the Effects of Diet on Health in Prediabetes With an Online Program

NCT02188823
View directory record Official record
Conditions
Prediabetes
Interventions
Low carbohydrate diet
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 29, 2026, 4:53 AM EDT