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Showing 1–24 of 448 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Positive airway pressure Clear all
Completed No phase listed Observational Accepts healthy volunteers

Mechanisms for Individual Differences in Hypertension in Obstructive Sleep

NCT03176732
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypertension
Interventions
Positive Airway Pressure
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 21, 2026, 10:49 PM EDT
Completed No phase listed Observational

The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.

NCT01512771
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Anxiety, Nightmares, Unrefreshed Sleep
Interventions
CPAP
Other
Lead sponsor
Northport Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2014 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional

Asthma and Obstructive Sleep Apnea (OSA)

NCT01026298
View directory record Official record
Conditions
Asthma, Obstructive Sleep Apnea
Interventions
FDA-Approved Treatment
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 73 Years
Enrollment
744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Nasal Airflow Pressure Optimization to Resolve Excessive Snoring

NCT01949584
View directory record Official record
Conditions
Snoring
Interventions
nasal continuous positive airway pressure less than or equal to 6 cm H2O
Device
Lead sponsor
inSleep Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Atlanta, Georgia • Baltimore, Maryland • Lanham, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Sep 21, 2026, 10:49 PM EDT
Completed No phase listed Observational

Delivery Room Practice Change Following the Initiation of the NICHD SUPPORT Trial

NCT01601886
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Luc Brion
Other
Eligibility
24 Weeks to 35 Weeks
Enrollment
3,843 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2012 · Synced Sep 21, 2026, 10:49 PM EDT
Terminated Phase 4 Interventional Results available

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

NCT00730041
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Pillar Palatal Implant System, Sham system
Device
Lead sponsor
Medtronic Xomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Little Rock, Arkansas • Berkeley, California • Denver, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2010 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Pilot Study on Pairing Sedation Strategies and Weaning

NCT02219659
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Sedation Protocol with Daily Interruption, Sedation Protocol Without Daily Interruption, Fentanyl Push First
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional

Autonomic Function in Obstructive Sleep Apnea

NCT00681161
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
continuous positive airway pressure (CPAP)
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants

NCT02249143
View directory record Official record
Conditions
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Interventions
CPAP and room air
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Up to 1 Year
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Phase 2 Interventional Results available

Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial

NCT01187771
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Laparoscopic Gastric Banding, Continuous Positive Airway Pressure
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Physiological Changes With High-Flow Nasal Cannula

NCT03700606
View directory record Official record
Conditions
Respiratory Distress Syndrome in Premature Infant
Interventions
High flow nasal cannula, Nasal CPAP
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 21, 2026, 10:49 PM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
26
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 21, 2026, 10:49 PM EDT
Terminated Not applicable Interventional

Esophageal Balloon Guided Weaning of the Morbidly Obese Patient

NCT02323009
View directory record Official record
Conditions
Morbid Obesity
Interventions
Esophageal Balloon, Cstat
Device · Other
Lead sponsor
East Carolina University
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Understanding the Sleep Apnea/Insomnia Interaction

NCT01824472
View directory record Official record
Conditions
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Interventions
CPAP, CBT, sham CPAP, CC
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional

Safety Study of Continuous Positive Airway Pressure Via a Nasal Mask

NCT01524614
View directory record Official record
Conditions
Upper Airway Obstruction
Interventions
nasal mask
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2017 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea

NCT00880165
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure apparatus
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 90 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Sleep Disordered Breathing, Obesity and Pregnancy Study (SOAP)

NCT02086448
View directory record Official record
Conditions
Obese, Pregnancy, Sleep Disordered Breathing
Interventions
CPAP, sham-CPAP, Sleep hygiene
Device · Other
Lead sponsor
Francesca Facco, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 21, 2026, 10:49 PM EDT
Active, not recruiting Not applicable Interventional

3D Printer Modified CPAP Mask for Obstructive Sleep Apnea

NCT03932383
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Custom CPAP mask
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Sep 21, 2026, 10:49 PM EDT
Terminated Not applicable Interventional Results available

Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis

NCT00537446
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Interventions
noninvasive positive pressure ventilation
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2020 · Synced Sep 21, 2026, 10:49 PM EDT
Terminated Not applicable Interventional

Extubation Readiness Study in Very Low Birthweight Infants

NCT01471431
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
spontaneous breathing trial
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
48 Hours to 14 Weeks
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment

NCT00252629
View directory record Official record
Conditions
Apnea, Sleep, Chronic Fatigue Syndrome
Interventions
Nasal CPAP treatment during sleep
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
32 Years to 52 Years · Male only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Sep 21, 2026, 10:49 PM EDT
Recruiting Not applicable Interventional

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

NCT04179981
View directory record Official record
Conditions
Sleep Apnea Syndrome, Obstructive Sleep Apnea, COPD, Overlap Syndrome, Quality of Life, Neurocognitive Function, Sleepiness, Elderly, Positive Airway Pressure
Interventions
Positive airway pressure, Conservative care (control arm)
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
668 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 21, 2026, 10:49 PM EDT
Completed Not applicable Interventional Results available

TPAP for Comfort in OSA

NCT06264128
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
TPAP, CPAP
Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Sep 21, 2026, 10:49 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

CPAP Population Management

NCT04559737
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Case Management
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 21, 2026, 10:49 PM EDT