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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:48 PM EDT

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Showing 1–24 of 389 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Present Pain Intensity Clear all
Completed Phase 1 Interventional

To Assess the Patients' Ability to Self-Administer Fasinumab

NCT03491904
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Fasinumab AI, Fasinumab PFS
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
23
States / cities
Gilbert, Arizona • Glendale, Arizona • Los Angeles, California + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Mood in Assisted Living Settings

NCT01763216
View directory record Official record
Conditions
Depressive Symptoms, Clinical Depression
Interventions
Road Tour, Boatload of Crosswords
Other
Lead sponsor
Marianne Smith
Other
Eligibility
55 Years and older
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
32
States / cities
Amana, Iowa • Bettendorf, Iowa • Carlisle, Iowa + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 30, 2026, 2:48 PM EDT
Active, not recruiting No phase listed Observational

Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery

NCT03408717
View directory record Official record
Conditions
Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
Interventions
Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment
Other
Lead sponsor
KK Women's and Children's Hospital
Government
Eligibility
21 Years to 80 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

ED Physical Therapy for Acute Low Back Pain

NCT04921449
View directory record Official record
Conditions
Low Back Pain
Interventions
ED Physical Therapy, Usual Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 30, 2026, 2:48 PM EDT
Terminated Not applicable Interventional

Pain Control in Patients With Recurrent or Metastatic Breast or Prostate Cancer

NCT00002668
View directory record Official record
Conditions
Breast Cancer, Pain, Prostate Cancer
Interventions
Observation, Educational Intervention and Behavioral Skills Training
Behavioral
Lead sponsor
Eastern Cooperative Oncology Group
Network
Eligibility
18 Years to 120 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 1998
U.S. locations
15
States / cities
Urbana, Illinois • Cedar Rapids, Iowa • Des Moines, Iowa + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 30, 2026, 2:48 PM EDT
Recruiting Not applicable Interventional

Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain

NCT06058624
View directory record Official record
Conditions
Chronic Pain
Interventions
Veteran ACT for Chronic Pain (VACT-CP), Online Pain School
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
West Haven, Connecticut • Bedford, Massachusetts • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Psychosocial Support for Pre-operative Pain and Distress

NCT03665727
View directory record Official record
Conditions
Acute Pain
Interventions
Mindfulness, Suggestion, Psychoeducation
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
727 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

NCT05589402
View directory record Official record
Conditions
Spinal Cord Injuries, Spine Disease, Stroke
Interventions
Lidocaine Cream 5%, Rehabilitation Movement Training
Drug · Other
Lead sponsor
University of Texas Rio Grande Valley
Other
Eligibility
18 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Harlingen, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

A Trial Comparing Different Dosing Regimens of Morphine in Patients With Moderate to Severe Pain

NCT00293969
View directory record Official record
Conditions
Pain
Interventions
Morphine 0.1mg/kg versus morphine 0.15 mg/kg
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2006 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Psychosocial Support for Acute Hospital Pain and Distress

NCT02590029
View directory record Official record
Conditions
Acute Pain
Interventions
Mindfulness, Suggestion, Psychoeducation
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 6, 2020 · Synced Oct 30, 2026, 2:48 PM EDT
Withdrawn Not applicable Interventional

Preoperative Mindfulness In Musculoskeletal Tumor

NCT04143529
View directory record Official record
Conditions
Musculoskeletal Malignancy
Interventions
Personalized acceptance-based mindfulness exercise, Brief educational pamphlet
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 30, 2026, 2:48 PM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 30, 2026, 2:48 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain

NCT00134225
View directory record Official record
Conditions
Neck Pain, Low Back Pain
Interventions
Muscle Pattern Recognition (MPR)
Device
Lead sponsor
iTech Medical, Inc.
Industry
Eligibility
18 Years to 62 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
3
States / cities
Irvine, California • Portage, Michigan • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 26, 2005 · Synced Oct 30, 2026, 2:48 PM EDT
Completed No phase listed Observational

The Effect of Primary Care Opioid Taper Plans on Sustained Opioid Taper

NCT03748862
View directory record Official record
Conditions
Opiate Replacement Therapy
Interventions
Taper Plan
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Social Presence and Perception in Virtual Reality on Pain

NCT03157362
View directory record Official record
Conditions
Chronic Pain, Widespread
Interventions
Near Non-Social, Near Social, Far Non-Social, Far Social
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Trial of the Effect of Timing of Cholecystectomy During Initial Admission for Mild Gallstone Pancreatitis

NCT02806297
View directory record Official record
Conditions
Pancreatitis
Interventions
Early cholecystectomy with IOC, Late cholecystectomy with IOC
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Collaborative Care to Alleviate Symptoms and Adjust to Illness in Chronic Heart Failure (CASA) Trial

NCT01739686
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
CASA Intervention
Other
Lead sponsor
Denver Research Institute
Other
Eligibility
18 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 30, 2026, 2:48 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction

NCT05519644
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Sleep Deprivation, Heart Rate, Sleep Monitoring, Diet, Exercise Performance, Surveys, McGill Pain Questionnaire, Shortened Profile of Mood States, Pittsburg Sleep Index, Cognitive performance, Marksmanship Performance, Quick Board, Advanced Medical Technologies Inc, Jump Test, CGM/CKM, Blood Draw, Ketone Supplement
Other · Behavioral · Biological + 1 more
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 30, 2026, 2:48 PM EDT
Completed No phase listed Observational

Comparison of the Accuracy of Telehealth Examination Versus Clinical Examination in the Detection of Rotator Cuff Tears

NCT03906630
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Telehealth clinical exam, Standard clinical exam
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
40 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Raleigh, North Carolina • Wake Forest, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 30, 2026, 2:48 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach

NCT03705715
View directory record Official record
Conditions
Neuropsychiatric Syndromes
Interventions
PET with radiotracer [11C]PBR-28 ( or [11C]ER176), Affective challenge
Drug · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 30, 2026, 2:48 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Preventing Loss of Independence Through Exercise in Community Living Centers

NCT06972004
View directory record Official record
Conditions
Dementia, Cognitive Dysfunction
Interventions
Preventing Loss of Independence through Exercise (PLIE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
288 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 30, 2026, 2:48 PM EDT
Completed Not applicable Interventional

MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace

NCT01978392
View directory record Official record
Conditions
Chronic Physical Health Conditions
Interventions
Self-management group workshops
Behavioral
Lead sponsor
Liberty Mutual Research Institute for Safety
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Worcester, Massachusetts • Hanover, New Hampshire • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 30, 2026, 2:48 PM EDT
Terminated Phase 2 Interventional Results available

[124I]FIAU PET-CT Scanning in Patients With Pain in a Prosthetic Knee or Hip Joint

NCT01705496
View directory record Official record
Conditions
Prosthetic Joint Infections
Interventions
[124I]FIAU
Radiation
Lead sponsor
BioMed Valley Discoveries, Inc
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
10
States / cities
Mobile, Alabama • Tucson, Arizona • Little Rock, Arkansas + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Oct 30, 2026, 2:48 PM EDT
Terminated Phase 2 Interventional

Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid

NCT04291599
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
Ketorolac, Opioid
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 30, 2026, 2:48 PM EDT