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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 1,740 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pressure control Clear all
Not listed Phase 2 Interventional

Spironolactone in CKD Enabled by Chlorthalidone: PILOT

NCT05222191
View directory record Official record
Conditions
Renal Insufficiency, Chronic Hypertension
Interventions
Spironolactone, Chlorthalidone, Placebo
Drug
Lead sponsor
Indiana Institute for Medical Research
Other
Eligibility
19 Years to 110 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional

Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes

NCT03925168
View directory record Official record
Conditions
End Stage Renal Disease, Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder, Compliance, Patient, Compliance, Medication, Mood, Pain, Energy Supply; Deficiency, Quality of Life, Blood Pressure, Heart Rate Fast
Interventions
Music therapy
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
New Orleans, Louisiana • Terrytown, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 29, 2026, 4:18 PM EDT
Terminated Not applicable Interventional

Nasal Bridge Pressure Injury Prevention

NCT04761679
View directory record Official record
Conditions
Pressure Ulcer of Skin, Pressure Injury
Interventions
Applying the Mepilex foam
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 64 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 29, 2026, 4:18 PM EDT
Recruiting Not applicable Interventional

Glaucoma Laser Assessment of Stability and Sustainability

NCT06963684
View directory record Official record
Conditions
Glaucoma
Interventions
Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT)
Device
Lead sponsor
Twin Cities Eye Consultants
Other
Eligibility
40 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Coon Rapids, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Phase 1 Interventional

Study of ANX007 in Participants With Primary Open-angle Glaucoma

NCT04188015
View directory record Official record
Conditions
Open Angle Glaucoma
Interventions
2.5mg ANX007, 5.0mg ANX007, Sham Procedure
Biological · Other
Lead sponsor
Annexon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Newport Beach, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 29, 2026, 4:18 PM EDT
Not yet recruiting Not applicable Interventional

Miniature In-line Respirator

NCT07768215
View directory record Official record
Conditions
Brain Death, Respiration, Artificial
Interventions
Hope inVent
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
1 Year to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)

NCT03687970
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory, Diode Laser fiber type Selective Stimulator, Quantitative sensory testing, Conditioned pain modulation efficiency, Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS)
Other · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Oct 29, 2026, 4:18 PM EDT
Terminated Not applicable Interventional

Stress Index to Individualize Mechanical Ventilation in ARDS

NCT02871102
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome
Interventions
Recruitment Maneuver with PEEP and Tidal Volume Optimization
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Oct 29, 2026, 4:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Blood Flow in Individuals With Down Syndrome

NCT03590665
View directory record Official record
Conditions
Down Syndrome
Interventions
Hand grip exercise and lower body negative pressure
Other
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years to 45 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 29, 2026, 4:18 PM EDT
Terminated Phase 2 Interventional Results available

Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)

NCT03273257
View directory record Official record
Conditions
Chronic Thromboembolic Pulmonary Hypertension, CTEPH
Interventions
Riociguat, Placebo, Pulmonary endarterectomy
Drug · Procedure
Lead sponsor
International CTEPH Association
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 29, 2026, 4:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Illinois Workplace Wellness Study

NCT03164330
View directory record Official record
Conditions
Employee Health and Well-being
Interventions
Workplace Wellness Program, Biometric Screening/HRA - No Compensation, Biometric Screening/HRA - Moderate Compensation, Biometric Screening/HRA - High Compensation, Wellness Activities - Low Compensation, Wellness Activities - High Compensation
Behavioral
Lead sponsor
National Bureau of Economic Research, Inc.
Other
Eligibility
18 Years and older
Enrollment
4,834 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 29, 2026, 4:18 PM EDT
Terminated Not applicable Interventional

Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD

NCT03255057
View directory record Official record
Conditions
Acute Exacerbation of COPD
Interventions
Hemolung Respiratory Assist System, Invasive mechanical ventilation
Device
Lead sponsor
Alung Technologies
Industry
Eligibility
40 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
32
States / cities
Sacramento, California • Denver, Colorado • Newark, Delaware + 28 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2022 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional

Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants

NCT02126501
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Gradual pressure wean
Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
26 Weeks to 32 Weeks
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Phenylephrine and Pulse Pressure Variability

NCT05011357
View directory record Official record
Conditions
Intraoperative Hypotension
Interventions
Phenylephrine, Saline Control
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional

SAMPAP Trial -Impact of a Novel Sleep Apnea Management Group Intervention on Positive Airway Pressure Adherence

NCT03835702
View directory record Official record
Conditions
Sleep Apnea
Interventions
SAM Clinic Intervention
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 29, 2026, 4:18 PM EDT
Active, not recruiting Not applicable Interventional

Community Intervention to Reduce CardiovascuLar Disease in Chicago

NCT04755153
View directory record Official record
Conditions
Hypertension
Interventions
Practice Facilitation, Non-Practice Facilitation
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 29, 2026, 4:18 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

NCT06498960
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
CereVasc eShunt System, VP Shunt
Device
Lead sponsor
CereVasc Inc
Industry
Eligibility
60 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
29
States / cities
Los Angeles, California • New Haven, Connecticut • Jacksonville, Florida + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lung-Resident Memory Th2 Cells in Asthma

NCT03455959
View directory record Official record
Conditions
Asthma, Allergic
Interventions
Bronchoscopy/BAL, Airway Brushing
Procedure
Lead sponsor
Andrew D. Luster, M.D.,Ph.D.
Other
Eligibility
18 Years to 55 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 29, 2026, 4:18 PM EDT
Not listed Not applicable Interventional

Stress Management for High Blood Pressure

NCT02371317
View directory record Official record
Conditions
Prehypertension
Interventions
Mindfulness-Based Stress Reduction, Stress Management Education, American Heart Association Recommended Self-Care
Behavioral · Other
Lead sponsor
Kent State University
Other
Eligibility
21 Years to 70 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Cleveland, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Perioperative Blood Pressure Screening to Improve Long-term Cardiovascular Health

NCT03634813
View directory record Official record
Conditions
Blood Pressure
Interventions
High Blood Pressure Monitor, Usual Care
Device · Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Oct 29, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Extension and Blood Pressure

NCT02929810
View directory record Official record
Conditions
Sleep Extension
Interventions
sleep extension, sleep maintenance
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 29, 2026, 4:18 PM EDT
Not listed No phase listed Observational

Psychosocial Determinants of Medication Adherence in Hypertensive African Americans

NCT00195182
View directory record Official record
Conditions
Hypertension
Interventions
Self affirmation and positive affect induction vs. control
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2008 · Synced Oct 29, 2026, 4:18 PM EDT
Recruiting Not applicable Interventional

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

NCT03901924
View directory record Official record
Conditions
Mechanical Ventilation Complication
Interventions
Volume Support Mode Mechanical Ventilation, Assist Control Mode Mechanical Ventilation
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 29, 2026, 4:18 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Reduced Volume of Inspiratory Resistance Training

NCT05744817
View directory record Official record
Conditions
Hypertension
Interventions
Inspiratory muscle strength training
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 29, 2026, 4:18 PM EDT