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ClinicalTrials.gov public records Last synced Nov 12, 2026, 5:20 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 98 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Pressure support ventilation Clear all

Conditions: Pediatric Asthma, Acute Asthma, BiPAP, Non-invasive Positive Pressure Ventilation
Interventions: Bilevel positive airway pressure ventilation; Device
Lead sponsor: Columbia University; Other
Eligibility: 5 Years to 17 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: New York, New York • Columbus, Ohio • Philadelphia, Pennsylvania

Conditions: Spontaneous Breathing Trial in ICU
Interventions: Pressure Support Ventilation (PSV), Automatic tube compensation (ATC); Other
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 880 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, Motivation
Interventions: Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET), Mobile Health intervention; Device · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cystic Fibrosis
Interventions: Pressure support ventilation; Device
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 12 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Sleep Apnea, Obstructive, Hypertension, Pulmonary, Heart Failure
Interventions: AirSense™ 10 AutoSet, Standard Medical Therapy; Device · Other
Lead sponsor: Albert Einstein Healthcare Network; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Respiratory Distress Syndrome (Neonatal), Surfactant
Interventions: Surfactant Administration Through Laryngeal or Supraglottic Airway (SALSA), Continuous Positive Airway Pressure (CPAP); Procedure
Lead sponsor: Sharp HealthCare; Other
Eligibility: 33 Weeks to 38 Weeks
Enrollment: 422 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 3
States / cities: Chula Vista, California • La Mesa, California • San Diego, California

Conditions: Coronary Artery Disease, Heart Failure
Interventions: continuous, mechanical ventilatory support; Procedure
Lead sponsor: Aurora BayCare Medical Center; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Green Bay, Wisconsin

Conditions: Obesity
Interventions: Positive end-expiratory pressure (PEEP), ZEEP; Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Failing Fontan Physiology, Pediatric Congenital Heart Disease
Interventions: Hayek RTX ventilator; Device
Lead sponsor: University of Michigan; Other
Eligibility: 10 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Spinal Cord Injury
Interventions: Non-invasive Ventilation(NIV), Sham Non-invasive ventilation(NIV); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 60 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Hypertension, Fall
Interventions: Tai Chi tailored for lowering blood pressure (PRESSURE), Tai Chi tailored for improving balance (BALANCE); Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 50 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Bloomfield, Connecticut

Conditions: Obesity Hypoventilation Syndrome
Interventions: AVAPS-AE Mode of Therapy, Respironics OnmiLab BiPAP S mode, Respironics OmniLab Advanced CPAP mode; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Tucson, Arizona • Chicago, Illinois

Conditions: Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
Interventions: Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%, Supplemental oxygen with target saturation of 91 to 95%; Drug · Device
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: 24 Weeks to 27 Weeks
Enrollment: 1,316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2016
U.S. locations: 22
States / cities: Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more

Conditions: Mechanical Ventilation
Interventions: Assist Control Mode and Pressure Support Mode Mechanical Ventilation; Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Dysphagia
Interventions: Laborie LMT Pharyngeal System (3.7 mm catheter), Medtronic ManoScan ESO HRM System (4.2 mm catheter); Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Mechanical Ventilation Complication
Interventions: weaning; Procedure
Lead sponsor: University of California, Los Angeles; Other
Eligibility: Not listed
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Acute Respiratory Distress Syndrome, Respiratory Failure
Interventions: Precision ventilation, Guided usual care ventilation; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 1,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 33
States / cities: Tucson, Arizona • Little Rock, Arkansas • La Jolla, California + 25 more

Conditions: Status Asthmaticus
Interventions: Noninvasive positive pressure ventilation; Other
Lead sponsor: Southern Illinois University; Other
Eligibility: 1 Year to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
Interventions: BiPAP, BiPAP/AVAPS (Phillips Respironics); Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Preterm Birth, Extreme Prematurity
Interventions: Sustained Inflation, Standard of Care; Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 23 Weeks to 26 Weeks
Enrollment: 460 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 9
States / cities: Loma Linda, California • Sacramento, California • San Diego, California + 5 more

Conditions: Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
Interventions: Vapotherm High Flow Therapy, Non-invasive positive pressure ventilation; Device
Lead sponsor: Vapotherm, Inc.; Industry
Eligibility: 50 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Prematurity, Respiratory Distress Syndrome
Interventions: RAM cannula ventilator CPAP, Occlusive interface bubble CPAP; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 12 Hours to 36 Hours
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Respiratory Distress Syndrome
Interventions: PSV+VG mode versus SIMV+VG mode; Procedure
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 72 Hours to 120 Hours
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Acute Respiratory Distress Syndrome
Interventions: ASV, Lung Protective Ventilation; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults

Stroke and CPAP Outcome Study 3

Pressure Support Ventilation During CF Exacerbations

Auto-PAP for Pulmonary Hypertension Treatment in Decompensated HF Patients With Sleep Apnea.

Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants

Study to Determine if Using Ventilation During Open Heart Surgery Improves Lung Outcomes

Effects of Different PEEP Levels on Work of Breathing in Morbidly Obese Patients Prior to and After Extubation

Noninvasive Negative Pressure Ventilation to Support Failing Fontan Physiology

Ventilatory Support to Improve Exercise Training in High Level Spinal Cord Injury

Health Outcomes of Two Different Tai Chi Interventions

AVAPS-AE Efficacy Study

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation

Standardizing Swallow Pressure Measurements

Mechanical Ventilator Weaning in Chronically Ventilated Patients

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

Non Invasive Positive Pressure Ventilation in Status Asthmaticus

Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury

Sustained Aeration of Infant Lungs Trial

High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)

Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates

Effects of Volume Guarantee With Pressure Supported vs. Synchronized Intermittent Mandatory Ventilation in VLBW Infants

Adaptive Support Ventilation in Acute Respiratory Distress Syndrome